Application NoteImproved Chromatographic Analysis of Oligonucleotides with ACQUITY PREMIER Oligonucleotide BEH C18 Columns

Application Note Improving Recovery and Quantitation of Oligonucleotide Impurities Using ACQUITY PREMIER with MaxPeak HPS Technology Brooke M. Koshel, Robert E. Birdsall, Ying Qing Yu Waters Corporation Abstract Ion-pair reversed-phase chromatography is a commonly used technique for the separation of…

Application Note Overcoming Non-Specific Adsorption in Oligonucleotide HILIC Analysis: A Comparison of Passivation and MaxPeak™ High-Performance Surfaces Technology Corey E. Reed, Tony Reinhold, Paula Hong Waters Corporation, United States Published on July 26, 2026 Abstract Oligonucleotides are essential tools in…

Application Note Mitigation of Non-Specific Adsorption During Column Conditioning for an Oligonucleotide HILIC Analysis Tony Reinhold, Martin Gilar, Andrew Steere, Paula Hong Waters Corporation Abstract Oligonucleotides, the short strands of nucleic acids that are pivotal in genetic research and therapeutic…

[ WHITE PAPER ] Low Adsorption HPLC Columns Based on MaxPeak High Performance Surfaces M. Lauber, T. H. Walter, M. Gilar, M. DeLano, C. Boissel, K. Smith, R. Birdsall, P. Rainville, J. Belanger, and K. Wyndham Waters Corporation, Milford, MA,…