A New Alternative to Gel Electrophoresis: Higher Resolution and Faster Analysis of Large Nucleic Acids by Rigorously Designed GTxResolveTM 250 Å Slalom Columns

Application Note Plasmid Topology and Digest Analysis Using a GTxResolve™ 250 Å Slalom Chromatography Column Jamuna Vaishnav, Balasubrahmanyam Addepalli, Matthew A. Lauber Waters Corporation, United States Published on August 18, 2025 Abstract This application note illustrates the characterization of plasmid…

Application Note Rapid and Sensitive Detection of dsRNA Contaminants in mRNA Using the GTxResolve™ 250Å Slalom Chromatography Column Jamuna Vaishnav, Matthew Lauber, Balasubrahmanyam Addepalli Waters Corporation, United States Published on August 29, 2025 Abstract Discovery and development of messenger RNA…

Application Note Slalom-Aided Anion Exchange Chromatography for Enhanced Analysis of Plasmid DNA Topological Impurities Abraham S. Finny, Fabrice Gritti, Szabolcs Fekete, Balasubrahmanyam Addepalli, Matthew A. Lauber Waters Corporation, United States Published on July 23, 2025 Abstract Slalom-Aided Anion Exchange Chromatography…

Best Poster Award Participant (Poster #304) Strong Anion-Exchange HPLC for Size-Range and Topology-Resolved Analysis of Nucleic Acids Abraham S. Finny*, Fabrice G. Gritti, Balasubrahmanyam Addepalli, Matthew A. Lauber *[email protected] Waters Corporation, Milford, MA, USA Strong AEX resolves nucleic acids from…