Characterization and Impurity Profiling of Combined Amylin and GLP-1 Analogs with RapiZyme Trypsin

Application Note One Pot, Mildly Acidic Digestion Protocols for Peptide Mapping Using Lys-C and RapiZyme™ Trypsin Caitlin M. Hanna, Stephan M. Koza, Michael Zagieboylo, Steve Shiner Waters Corporation, United States Published on August 27, 2025 Abstract Peptide mapping of therapeutic…

Peptide Mapping for Biotherapeutics Strategies for Simplifying Protein Digestion A sponsored publication from Peptide Mapping Doesn’t Need to Be Complex Introducing PeptideWorks™ Tryptic Protein Digestion Kits PeptideWorks Tryptic Protein Digestion Kits uniquely deliver automatable, high efficiency, reproducible peptide maps in…

Application Note Unlocking Robust, Reproducible Separations for Modern Peptide Therapeutics with BioResolve™ Peptide Phenyl Hexyl+ Columns Emery Domain, Caitlin Hanna, Steve Shiner Waters Corporation, United States Published on July 09, 2026 Abstract This application note describes the performance of the…

Application Note Versatile and Rapid Digestion Protocols for Biopharmaceutical Characterization Using RapiZyme™ Trypsin Samantha Ippoliti, Nick Zampa, Ying Qing Yu, Matthew A. Lauber Waters Corporation Abstract Complete and clean trypsin digestion is achieved with an enzyme that provides a balance…