Development of Separation Methods for GLP-1 Synthetic Peptides Utilizing a Systematic Protocol and MaxPeak High Performance Surface Technology

Application Note Development of Separation Methods for GLP-1 Synthetic Peptides Utilizing a Systematic Protocol and MaxPeak™ High Performance Surface Technology Brianna R Clements, Paul D. Rainville Waters Corporation Abstract GLP-1s are synthetic peptide drugs used to treat type-II diabetes and…

M1030-01-01 Development of Improved Chromatographic Methods for the Separation of Synthetic Peptides Medications and Associated Impurities Paul Rainville, Brianna Clements, and Adam Bengtson Waters Corporation 34 Maple Street Milford MA 01757 USA CONTACT INFORMATION: [email protected]. PURPOSE Glucagon-Like Peptide-1 agonists (GLP-1s)…

ADVANCING ANALYTICAL PERFORMANCE FOR BIOTHERAPEUTICS WITH A BIO-INERT HPLC SYSTEM Pawel Bigos, Xiangsha Du, Duanduan Han, Robert Birdsall, Karen Nyholm Waters Corporation INTRODUCTION RESULTS AND DISCUSSION In biopharmaceutical analysis, undesired secondary analyte/ surface interactions have hindered performance in HPLC. Analytes…

Application Note Method Development for the Chromatographic Separation of Synthetic Cyclic Peptides and Impurities Utilizing a Systematic Protocol and MaxPeak High Performance Surface Technology Adam Bengtson, Paul D. Rainville, Stephanie Harden Waters Corporation Abstract Waters has developed a systematic protocol,…