Development of Improved Chromatographic Methods for the Separation of Synthetic Peptides Medications and Associated Impurities

Application Note Development of Separation Methods for GLP-1 Synthetic Peptides Utilizing a Systematic Protocol and MaxPeak™ High Performance Surface Technology Brianna R Clements, Paul D. Rainville Waters Corporation Abstract GLP-1s are synthetic peptide drugs used to treat type-II diabetes and…

Development of Separation Methods for GLP-1 Synthetic Peptides Utilizing a Systematic Protocol and MaxPeak High Performance Surface Technology XSelect Premier 0.40 0.130 0.00 9.00 0.120 AU 0.06 0.04 21.50 0.100 0.090 0.080 0.070 0.060 0.050 0.040 21.60 21.70 21.80 21.90…

Workflow Solutions for Peptide Therapeutics Application Compendium Table of Contents Introduction4 An emerging class of peptide therapeutics: GLP-15 Analytical advances in peptide therapeutics5 Key analyses for synthetic and recombinant peptide therapeutics 6 Types of impurities in peptide therapeutics 7 Agilent…

Application Note Leveraging the Alliance™ iS Bio HPLC System as a Modern HPLC for Peptide Drug Substances Analysis in QC Environments Duanduan Han, Robert E. Birdsall, Karen Nyholm Waters Corporation Abstract The Alliance iS Bio HPLC System with MaxPeak™ High…