Separation of Impurities from a Fully Phosphothioated and 2’-O-methylated RNA Using Ion-Pair Reversed- Phase Chromatography

Thermo Scientific DNAPac Family of Columns Superior Oligonucleotide Analysis DNAPac RP 2016 DNAPac PA200 RS 2013 DNASwift SAX-1S 2009 For over 30 years, the Thermo Scientific™ DNAPac™ family of columns has been the go-to for high resolution U/HPLC separation of…

Oligonucleotide Analysis: Practical Techniques and Method Development Optimization for HPLC Mohit Patel LC Columns and Consumables Technical Support December 19, 2023 1 12/19/2023 DE # DE48216954 What Are Oligonucleotide Therapeutic Types? Oligonucleotides are being increasingly developed as therapeutics against a…

Application News LabSolutions™ MD : Software for Efficient Method Development based on Analytical Quality by Design Efficient Method Development of Oligonucleotides by Reversed-Phase Ion-Pair Chromatography Shinichi Fujisaki and Risa Suzuki User Benefits  LabSolutions MD can improve the efficiency of…

Application note | 001398 Biopharma Streamlining characterization and monitoring of oligonucleotide impurities using an Orbitrap-based LC-HRAM-MS platform Application benefits Authors Hao Yang , Keeley Murphy , Yi Zhang , 1 2 3 • Comprehensive characterization of oligonucleotides and their impurities…