Oligonucleotide Analysis: Practical Techniques and Method Development Optimization for HPLC

Fast and High-Resolution Reversed-Phase Separation of Synthetic Oligonucleotides High-pH-stable, superficially porous particle columns for LC/UV and LC/MS Application Note Biologics and Biosimilars Authors Introduction Phu Duong, Brian A. Bidlingmeyer, Synthetic DNA- and RNA-based oligonucleotides are among many successful biotherapeutic drugs…

Oligonucleotide Purification Solutions Agilent PLRP-S and PL-SAX HPLC columns R + + R + R R + PL-SAX 1000 Å Pore Size 1000 Å PLRP-S 1000 Å Pore Size 1000 Å It’s All About Scalability Whether you’re working on the…

Agilent AdvanceBio Oligonucleotide Columns and Oligonucleotide Standards IMPROVE RELIABILITY. REDUCE COSTS. INCREASE FLEXIBILITY. AGILENT ADVANCEBIO OLIGONUCLEOTIDE COLUMNS AND OLIGONUCLEOTIDE STANDARDS HIGH-RESOLUTION OLIGONUCLEOTIDE SEPARATIONS WITH LONG COLUMN LIFETIME ON HPLC AND UHPLC SYSTEMS Synthetic oligonucleotides are promising therapeutic agents for the…

An Introduction to Ion-Paired Reverse-Phase Oligonucleotide Separations: From Analysis to Purification Melissa Goodlad, PhD Columns and Supplies Applications Engineer April 15, 2025 1 April 15, 2025 An Introduction to Ion-Paired Reverse-Phase Oligonucleotide Separations DE-006001 Introduction to Ion-Paired Reverse-Phase (IP-RP) Separations…