VISUALIZATION AND QUANTIFICATION OF DRUG/METABOLITES BY SENSITIVE AND FAST TARGETED DESI IMAGING ON TQ SYSTEM

NOVEL TARGETED DESI MRM TQ SYSTEM PROVIDING INCREASED SENSITIVITY AND ACQUISITION SPEED FOR MASS SPECTROMETRY IMAGING Emmanuelle Claude1, Steven Pringle1, Joanne Ballantyne1 1 Waters Corporation, Wilmslow, UK INTRODUCTION Gefitinib was detected with a S/N ~ 2,500 and was at least…

IMPROVING SPATIAL DISTRIBUTION, SENSITIVITY AND SELECTIVITY IN MSI, USING A NOVEL DESI QQQ AND A HR-MULTI REFLECTING TOF SYSTEMS Emmanuelle Claude1; Farid Jahouh2; Martin Palmer1; Inneke Wynant2; Filip Cuyckens2, Marjolein Van Heerden2; Jan Claereboudt3; Rob J Vreeken2,4, Lance Nicolaysen5 1…

IMPROVED SELECTIVITY AND ACQUISITION SPEED USING DESI QUADRUPOLE BASED MASS SPECTROMETER 1 Emmanuelle Claude, 1Wei Rao, 2Zoltan Takats, 1Emrys Jones 1 Waters Corporation, Wilmslow, UK; 2Department of Metabolism, Digestion and Reproduction, Imperial College London, South Kensington Campus, London, UK INTRODUCTION…

Application Note Visualization of Gefitinib and Related Metabolites in Rat Liver Using DESI-Tandem Quadrupole Mass Spectrometry Robert Plumb, Anthony Midey Waters Corporation, United States Published on August 07, 2026 Abstract Detection and measurement of drugs, their metabolites, and biomarkers in…