Versatile and Rapid Digestion Protocols for Biopharmaceutical Characterization Using RapiZyme™ Trypsin

IMPROVED BIOPHARMACEUTICAL PEPTIDE MAPPING WORKFLOWS USING A NOVEL AUTOLYSIS-RESISTANT TRYPSIN ENZYME Samantha Ippoliti1, Nick Zampa1, Ying Qing Yu1, Matthew A Lauber1, Leslie Napoletano1, Scott Berger1 Waters Corporation, Milford, MA METHODS Peptide mapping provides a wealth of information about a protein…

Peptide Mapping for Biotherapeutics Strategies for Simplifying Protein Digestion A sponsored publication from Peptide Mapping Doesn’t Need to Be Complex Introducing PeptideWorks™ Tryptic Protein Digestion Kits PeptideWorks Tryptic Protein Digestion Kits uniquely deliver automatable, high efficiency, reproducible peptide maps in…

Application Note One Pot, Mildly Acidic Digestion Protocols for Peptide Mapping Using Lys-C and RapiZyme™ Trypsin Caitlin M. Hanna, Stephan M. Koza, Michael Zagieboylo, Steve Shiner Waters Corporation, United States Published on August 27, 2025 Abstract Peptide mapping of therapeutic…

[ PEPTIDE MAPPING KITS ] Protein Digestion, Gets Intelligent… Achieve fast, automatable, reproducible peptide maps with a more complete and specific digestion Fast Peptide Mapping in Under 2.5 Hours... PeptideWorks™ Tryptic Protein Digestion Kits provide automatable, high efficiency, and reproducible…