Plasma proteomics goes high throughput – timsTOF Pro with PASEF and 4D feature alignment to quantify 500 plasma proteins in 11.5 min

High throughput 4D-Proteomics – Application of dia-PASEF® and the Evosep One for short gradients The timsTOF Pro offers a combination of two unique technologies, namely a 4th dimension provided by Trapped Ion Mobility Spectrometry (TIMS) to enhance ion separation and…

APPLICATION NOTE No. 73194 High-throughput plasma proteomics: A standardized and scalable workflow for quantitative protein profiling in large sample cohorts Keywords Q Exactive, Orbitrap, protein biomarker, plasma workflow, serum workflow, Evosep, high throughput proteomics workflow Authors Jing Wang1; Sarah Trusiak1;…

timsTOF Pro with PASEF and Evosep One: Maximizing throughput, robustness and analytical depth for shotgun proteomics The timsTOF Pro powered by PASEF enables sequencing speed of > 120 Hz, high sensitivity and robustness as well as an additional dimension of…

High throughput proteomics – Application of dia-PASEF and Evosep One for short gradients ASMS 2020, MP122 Stephanie Kaspar-Schoenefeld1, Markus Lubeck1, Thomas Kosinski1, Scarlet Koch1, Oliver Raether1, Gary Kruppa1 1Bruker Daltonik GmbH, 28359 Bremen, Germany Introduction Data-independent acquisition (DIA) promises reproducible…