High-throughput plasma proteomics: A standardized and scalable workflow for quantitative protein profiling in large sample cohorts

APPLICATION NOTE 65952 A robust mass spectrometer for precision medicine – the Orbitrap Exploris 240 mass spectrometer for large-scale plasma protein profiling Authors: Michelle L Dubuke1, Sitara Chauhan1, Sarah Trusiak1, and Emily I. Chen1 1 Thermo Fisher Scientific Precision Medicine…

An Ultra High-throughput Plasma Protein Profiling (uHTPPP) Workflow Using a Modified Quadrupole-Orbitrap Mass Spectrometer Michelle L. Dubuke1, Sarah Trusiak1, Sitara Chauhan1, Ryan D. Bomgarden2, Sergei Snovida2, Bhavin Patel2, Emily I. Chen1. 1Thermo Fisher Scientific, Precision Medicine Science Center, Cambridge, MA.…

APPLICATION NOTE 65727 Sampling the human population – ultra-highthroughput plasma protein profiling (uHTPPP) sample preparation for translational proteomics Authors: Sarah Trusiak,1 Sergei Snovida,2 Bhavin Patel,2 Ryan Bomgarden,2 Emily I. Chen,1 1 Thermo Fisher Scientific Precision Medicine Science Center, Cambridge, MA,…

TP 744 High Throughput Abundant Protein Depletion for Plasma Proteomics Amarjeet Flora, Anastasia Klenke, Bhavin Patel, Ryan Bomgarden Thermo Fisher Scientific, Rockford, IL, USA, 61101 Abstract Results Biological fluids like plasma are widely used for proteomics-based disease biomarker discovery. However,…