Performance Comparison of a Gradient Method Using a Microbore (1 mm Internal Diameter) column on ACQUITY UPLC and Competitive UHPLC Instrumentation

[ WHITE PAPER ] Dwell Volume and Extra-Column Volume: What Are They and How Do They Impact Method Transfer? Paula Hong and Patricia R. McConville Waters Corporation, Milford, MA, USA A chromatographic separation is impacted by numerous factors, including the…

[ APPLICATION NOTEBOOK ] SIZE-EXCLUSION CHROMATOGRAPHY (SEC) OF PEPTIDES, PROTEINS, AND AAVs [ SIZE-EXCLUSION CHROMATOGRAPHY ] [ SIZE-EXCLUSION CHROMATOGRAPHY ] Introduction Gel-permeation chromatography (GPC), size-exclusion chromatography (SEC), and gel-filtration chromatography (GFC) are commonly used terms to describe a liquid chromatographic…

[ UPLC AND UPLC/MS Application Notebook ] 1 [ ] THE COMPETITION STILL HASN’T SHOWN UP. FOR ULTIMATE PERFORMANCE, ® ©2009 Waters Corporation. Waters, ACQUITY UPLC, and The Science of What’s Possible are trademarks of Waters Corporation. 2 Today, more…

[ APPLICATION NOTE ] Scaling of a USP Assay for Quetiapine Fumarate Across Different Liquid Chromatographic Systems Amanda B. Dlugasch, Jennifer Simeone, and Patricia R. McConville Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ The Waters Column Calculator enables…