Dwell Volume and Extra-Column Volume: What Are They and How Do They Impact Method Transfer?

[ APPLICATION NOTE ] Evaluating the Performance of the ACQUITY Arc Bio UHPLC System for the Size-Exclusion Chromatography Analysis of a Monoclonal Antibody Corey E. Reed, Stephan M. Koza, and Weibin Chen Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■…

[ TECHNOLOGY BRIEF ] Evaluating HPLC, UHPLC, and UPLC System Performance Using a Reversed-Phase Method for Peptides Brooke M. Koshel, Robert E. Birdsall, and Ying Qing Yu Waters Corporation, Milford, MA, USA Modern LC systems having lower system dispersion offer…

Scaling Reverse-Phase and Hydrophilic Interaction Liquid Chromatography (HILIC) Methods to HPLC Authors: Margaret Maziarz, Paul Rainville, Stephanie Harden Affiliations: Waters Corporation, 34 Maple Street, Milford MA 01757 2.0 mL/min Step Time %A 1 Initial 90.0 %B 5.0 %C Curve 5.0…

[ APPLICATION NOTE ] Scaling of a USP Assay for Quetiapine Fumarate Across Different Liquid Chromatographic Systems Amanda B. Dlugasch, Jennifer Simeone, and Patricia R. McConville Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ The Waters Column Calculator enables…