Scaling of a USP Assay for Quetiapine Fumarate Across Different Liquid Chromatographic Systems

[ APPLICATION NOTE ] Gradient Method Scaling for Life Cycle Management of a USP Impurities Method Amanda B. Dlugasch, Jennifer Simeone, and Patricia R. McConville Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ The Waters™ Columns Calculator enables Pharmaceutical…

[ APPLICATION NOTE ] Transfer of USP Assay for Quetiapine Fumarate Across Different Liquid Chromatographic Systems Amanda B. Dlugasch, Jennifer Simeone, and Patricia R. McConville Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ INTRODUCTION The Alliance HPLC, ACQUITY Arc…

[ APPLICATION NOTE ] Scaling USP Methods to Smaller Particle Columns on the Alliance HPLC System Amanda B. Dlugasch, Jennifer Simeone, and Patricia R. McConville Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ INTRODUCTION Reduce run time and solvent…

Application Note Taking Advantage of 12k psi Pressure Capabilities for Modernizing USP Methods on the Alliance™ iS HPLC System Amanda B. Dlugasch, Paula Hong Waters Corporation, United States Published on August 19, 2025 Abstract Pharmaceutical companies frequently use compendial high…