SQUAD metabolomics combines targeted quantitation and untargeted discovery in a single Orbitrap MS experiment, delivering confident quantitative results alongside broad metabolite profiling.

Discover how ion sources shape LC-MS performance and why electrospray transformed modern mass spectrometry. Explore EASY-Spray™, NanoSpray Flex™, and the new OptiSpray™ technology.

A single LC-HRMS method for NDSRI quantitation across six beta blockers. Discover how Orbitrap MS enables sensitive, robust analysis of trace nitrosamine impurities.

How can mAb manufacturing monitoring be simplified? Switchable 2D-LC-UV-MS workflows enable near real-time tracking of critical quality attributes and faster process decisions.

HRAM Orbitrap LC-MS accelerates postmortem toxicology, enables retrospective screening for emerging drugs, and improves confidence in complex sample analysis.

Nick Riley’s group at the University of Washington uses Orbitrap Ascend and Vanquish Neo platforms to advance glycoproteomics through real-time LC-MS decision making.

This study shows nanoflow ESI-MS signal intensity is robust within 1–2 mm of optimal emitter position, improving proteomics workflow stability.

Upgrade your LC-MS with Thermo Fisher Scientific’s Trade-In / Trade-Up Program. Reduce costs, boost performance, and transition seamlessly to advanced mass spectrometry solutions.

This week we bring you application notes by Agilent Technologies, KNAUER, Shimadzu and Waters Corporation and technical note by Thermo Fisher Scientific!

Non-targeted PFAS analysis using Orbitrap HRAM and Compound Discoverer 3.5 enables confident identification of thousands of PFAS through advanced libraries, scoring tools and visualization workflows.