Propionic acid increases peptide identifications by 39% versus formic acid in LC-MS proteomics while maintaining chromatographic performance and compatibility.

Discover how Orbitrap Charge Detection MS and a multi-enzyme workflow characterize PEGylated therapeutic proteins by determining PEG stoichiometry, mapping attachment sites, and detecting impurities.

Discover how ion sources shape LC-MS performance and why electrospray transformed modern mass spectrometry. Explore EASY-Spray™, NanoSpray Flex™, and the new OptiSpray™ technology.

A single LC-HRMS method for NDSRI quantitation across six beta blockers. Discover how Orbitrap MS enables sensitive, robust analysis of trace nitrosamine impurities.

How can mAb manufacturing monitoring be simplified? Switchable 2D-LC-UV-MS workflows enable near real-time tracking of critical quality attributes and faster process decisions.

HRAM Orbitrap LC-MS accelerates postmortem toxicology, enables retrospective screening for emerging drugs, and improves confidence in complex sample analysis.

Upgrade your LC-MS with Thermo Fisher Scientific’s Trade-In / Trade-Up Program. Reduce costs, boost performance, and transition seamlessly to advanced mass spectrometry solutions.

This study introduces an MS/MS filtering tree workflow to distinguish bile acid isomers in LC-MS/MS data using ion intensity ratios and a web-based tool.

Non-targeted PFAS analysis using Orbitrap HRAM and Compound Discoverer 3.5 enables confident identification of thousands of PFAS through advanced libraries, scoring tools and visualization workflows.

How MSⁿ spectral libraries like mzCloud help identify substructures in unknown compounds. Learn how fragmentation data can guide structure elucidation and support identification of complex molecules.