New Synthetic Approach to C‑30 Ethers, Esters, and Amines of Betulin Using the Mitsunobu Reaction and Biological Evaluation of the Products
LCMSICPMSScientific article | Science and research

New Synthetic Approach to C‑30 Ethers, Esters, and Amines of Betulin Using the Mitsunobu Reaction and Biological Evaluation of the Products

This study introduces an efficient Mitsunobu-based synthesis of C-30 betulin derivatives and identifies promising compounds with broad anticancer activity.
New Synthetic Approach to C‑30 Ethers, Esters, and Amines of Betulin Using the Mitsunobu Reaction and Biological Evaluation of the Products
Residue-Level Determination of Small-Molecule–Protein Affinities by Hydrogen–Deuterium Exchange Mass Spectrometry
LCMSScientific article | Science and research

Residue-Level Determination of Small-Molecule–Protein Affinities by Hydrogen–Deuterium Exchange Mass Spectrometry

This study introduces an HDX-MS titration workflow for quantifying protein–ligand affinities at global, peptide, and residue resolution.
Residue-Level Determination of Small-Molecule–Protein Affinities by Hydrogen–Deuterium Exchange Mass Spectrometry
Tracking Protein Misfolding and Oligomerization: A Temperature-Controlled Ion Mobility-Mass Spectrometry Approach
LCMSScientific article | Science and research

Tracking Protein Misfolding and Oligomerization: A Temperature-Controlled Ion Mobility-Mass Spectrometry Approach

This study uses temperature-controlled IM-MS to monitor protein unfolding and oligomer formation in real time, revealing early aggregation pathways.
Tracking Protein Misfolding and Oligomerization: A Temperature-Controlled Ion Mobility-Mass Spectrometry Approach
News from LabRulezLCMS Library - Week 28, 2026
LCMSArticle | Poster

News from LabRulezLCMS Library - Week 28, 2026

This week we bring you application notes by Agilent Technologies and Metrohm and posters by Shimadzu/ASMS, Thermo Fisher Scientific/ASMS and Waters Corporation/ASMS!
News from LabRulezLCMS Library - Week 28, 2026
News from LabRulezLCMS Library - Week 24, 2026
LCMSArticle | Application

News from LabRulezLCMS Library - Week 24, 2026

This week we bring you application notes by Agilent Technologies, KNAUER and Shimadzu, other document by Thermo Fisher Scientific and poster by Waters Corporation/ASMS!
News from LabRulezLCMS Library - Week 24, 2026
News from LabRulezLCMS Library - Week 23, 2026
LCMSArticle | Application

News from LabRulezLCMS Library - Week 23, 2026

This week we bring you technical note by Agilent Technologies, application notes by KNAUER and Shimadzu, brochure by Thermo Fisher Scientific and poster by Waters Corporation!
News from LabRulezLCMS Library - Week 23, 2026
News from LabRulezGCMS Library - Week 22, 2026
GCMSArticle | Application

News from LabRulezGCMS Library - Week 22, 2026

This week we bring you application note by Shimadzu, presentation by MDCW / University of Washington and poster by Waters Corporation!
News from LabRulezGCMS Library - Week 22, 2026
Characterization of Asian lacquers by atmospheric solids analysis probe high resolution tandem mass spectrometry coupled with cyclic ion mobility separation
LCMSGCMSScientific article | Science and research

Characterization of Asian lacquers by atmospheric solids analysis probe high resolution tandem mass spectrometry coupled with cyclic ion mobility separation

This study uses ASAP-IMS-HRMS to characterize and classify Asian lacquers by origin, detecting phenols, pigments, and resins in historical samples.
Characterization of Asian lacquers by atmospheric solids analysis probe high resolution tandem mass spectrometry coupled with cyclic ion mobility separation
News from LabRulezLCMS Library - Week 05, 2026
LCMSArticle | Application

News from LabRulezLCMS Library - Week 05, 2026

This week we bring you application notes by Agilent Technologies, Shimadzu, Thermo Fisher Scientific and Waters Corporation!
News from LabRulezLCMS Library - Week 05, 2026
News from LabRulezLCMS Library - Week 37, 2025
LCMSArticle | Application

News from LabRulezLCMS Library - Week 37, 2025

This week we bring you application notes by Agilent Technologies and Shimadzu and posters by Thermo Fisher Scientific and Waters Corporation!
News from LabRulezLCMS Library - Week 37, 2025