Boosting Productivity in Toxicology Labs
LCMSArticle | Application

Boosting Productivity in Toxicology Labs

How do you boost toxicology productivity without sacrificing sensitivity? LC-MS/MS workflows enable rapid analysis of a broad range of drugs in 5–7 minutes.
Boosting Productivity in Toxicology Labs
Unlock High-Performance LC-MS with Factory-Certified Systems from Thermo Fisher Scientific
LCMSArticle | Product

Unlock High-Performance LC-MS with Factory-Certified Systems from Thermo Fisher Scientific

Get legendary Thermo Scientific LC-MS performance at a fraction of the cost. Factory-certified pre-owned systems deliver reliability, full warranty, expert support, and a smarter, sustainable investment.
Unlock High-Performance LC-MS with Factory-Certified Systems from Thermo Fisher Scientific
Unlocking Phytoplankton Metallomes with Comparative Analysis of Metal Quotas, Quantitative Proteomics, and Inferred Metalloproteomes
ICPMSLCMSScientific article | Science and research

Unlocking Phytoplankton Metallomes with Comparative Analysis of Metal Quotas, Quantitative Proteomics, and Inferred Metalloproteomes

This study integrates metal quotas, quantitative proteomics, and inferred metalloproteomes to reveal trace metal requirements and adaptation strategies in phytoplankton.
Unlocking Phytoplankton Metallomes with Comparative Analysis of Metal Quotas, Quantitative Proteomics, and Inferred Metalloproteomes
Dissecting Heterogeneous Populations of Protein-Complex Samples Using Direct Mass Technology
LCMSScientific article | Science and research

Dissecting Heterogeneous Populations of Protein-Complex Samples Using Direct Mass Technology

This study demonstrates Orbitrap-based CDMS/Direct Mass Technology as a quantitative tool for resolving and analyzing heterogeneous protein complexes below 100 kDa.
Dissecting Heterogeneous Populations of Protein-Complex Samples Using Direct Mass Technology
Reduce Sample Waste in the Lab Using Real-Time Data Evaluation with Automated Reactions
LCMSArticle | Software

Reduce Sample Waste in the Lab Using Real-Time Data Evaluation with Automated Reactions

Reduce sample waste and prevent data loss in LC-MS analysis using real-time data evaluation with system suitability testing and intelligent run control in Chromeleon software.
Reduce Sample Waste in the Lab Using Real-Time Data Evaluation with Automated Reactions
Regenerating liver uses ammonia to support de novo pyrimidine synthesis and cell proliferation
LCMSScientific article | Science and research

Regenerating liver uses ammonia to support de novo pyrimidine synthesis and cell proliferation

Regenerating liver redirects ammonia metabolism to fuel de novo pyrimidine synthesis, enabling cell proliferation and tissue repair after hepatectomy through metabolic reprogramming.
Regenerating liver uses ammonia to support de novo pyrimidine synthesis and cell proliferation
Determination of Chemical Mixtures in Environmental, Food, and Human Samples Using High-Resolution Mass Spectrometry-Based Suspect Screening Approaches
GCMSLCMSScientific article | Science and research

Determination of Chemical Mixtures in Environmental, Food, and Human Samples Using High-Resolution Mass Spectrometry-Based Suspect Screening Approaches

Suspect screening using LC- and GC-HRMS identified 547 chemicals across environmental, food, and human samples. Pharmaceuticals, pesticides, and personal care products were the most frequent contaminants.
Determination of Chemical Mixtures in Environmental, Food, and Human Samples Using High-Resolution Mass Spectrometry-Based Suspect Screening Approaches
Collision-Based Ion-activation and Dissociation
LCMSArticle | Academy

Collision-Based Ion-activation and Dissociation

Collision-based ion activation, developed nearly 80 years ago, remains the most widely used fragmentation method. Learn about three key techniques on Thermo Scientific MS.
Collision-Based Ion-activation and Dissociation
Ion-Pairing Hydrophilic Interaction Chromatography for Impurity Profiling of Therapeutic Phosphorothioated Oligonucleotides
LCMSScientific article | Science and research

Ion-Pairing Hydrophilic Interaction Chromatography for Impurity Profiling of Therapeutic Phosphorothioated Oligonucleotides

Ion-pairing HILIC improves impurity profiling of therapeutic oligonucleotides. It resolves deaminated impurities from full-length products, beyond current LC-MS limits.
Ion-Pairing Hydrophilic Interaction Chromatography for Impurity Profiling of Therapeutic Phosphorothioated Oligonucleotides
Mucinomics: The Next Frontier of Mass Spectrometry
LCMSArticle | Science and research

Mucinomics: The Next Frontier of Mass Spectrometry

Dr. Stacy Malaker shared advances in mucin characterization, enrichment, and their role in disease research during a Nature webinar. Here are the key takeaways.
Mucinomics: The Next Frontier of Mass Spectrometry