This study presents a sensitive LC-HRMS method for sequence verification and impurity profiling of RNA-based therapeutics.

Upgrade your LC-MS with Thermo Fisher Scientific’s Trade-In / Trade-Up Program. Reduce costs, boost performance, and transition seamlessly to advanced mass spectrometry solutions.

This week we bring you application notes by Agilent Technologies, KNAUER, Shimadzu and Waters Corporation and technical note by Thermo Fisher Scientific!

Non-targeted PFAS analysis using Orbitrap HRAM and Compound Discoverer 3.5 enables confident identification of thousands of PFAS through advanced libraries, scoring tools and visualization workflows.

How MSⁿ spectral libraries like mzCloud help identify substructures in unknown compounds. Learn how fragmentation data can guide structure elucidation and support identification of complex molecules.

How do you boost toxicology productivity without sacrificing sensitivity? LC-MS/MS workflows enable rapid analysis of a broad range of drugs in 5–7 minutes.

Get legendary Thermo Scientific LC-MS performance at a fraction of the cost. Factory-certified pre-owned systems deliver reliability, full warranty, expert support, and a smarter, sustainable investment.

Reduce sample waste and prevent data loss in LC-MS analysis using real-time data evaluation with system suitability testing and intelligent run control in Chromeleon software.

Sheffield researchers validated Thermo Scientific Tox Explorer for LC-MS/MS drug screening in post-mortem vitreous humor, confirming its sensitivity, stability and forensic value.

LC-HRMS screening combined with temporal clustering identified daily domestic discharge patterns in wastewater, enabling improved interpretation of population chemical exposure.