LC-MS Profiling of IgG2 Isoforms Using Difluoroacetic Acid and Reversed-Phase Chromatography

[ APPLICATION NOTE ] Comparing Mobile Phase Additives for the Separation of mAb Tryptic Peptides: A Case Study on Formic, Difluoroacetic, and Trifluoroacetic Acid Jennifer M. Nguyen, Xiaoxiao Liu, and Matthew A. Lauber Waters Corporation, Milford, MA, USA APPLICATION BENEFITS…

[ APPLICATION NOTE ] Improving the Recovery of Intact Antibodies from Reversed-Phase Separations Using a BioResolve RP mAb Polyphenyl Column Ximo Zhang, Robert Birdsall, and Ying Qing Yu Waters Corporation, Milford, MA, USA APPLICATION BENEFITS INTRODUCTION Method for improving the…

UNIVERSITY OF COPENHAGEN FA C U LT Y O F S C I E N C E Enhancing Subunit-Level Profiling of mAbs and ADCs with MSQuality Difluoroacetic Acid Jennifer Nguyen1,2, Jacquelynn Smith3, Olga V. Friese3, Jason C. Rouse4, Daniel P.…

Application Note Analysis of Adenoviral Vector Proteins by RPLC, Native Fluorescence, and Online MS Matthew A. Lauber, Colette Quinn Waters Corporation This is an Application Brief and does not contain a detailed Experimental section. Abstract Adenovirus (AdV) is being used…