A Fully Automated Robotic Set-Up based on Ultrahigh-Resolution QTOF Mass Spectrometry for Hydrogen Exchange Experiments

Conformational Characterization of Calmodulin by Hydrogen Deuterium Exchange Mass Spectrometry Joomi Ahn, Martha Stapels, Michael Eggertson, Keith Fadgen, and Ying Qing Yu Waters Corporation, Milford, MA, U.S. A P P L I C AT I O N B E N…

Poster # P-I-0178 Probe the protein conformation using top-down hydrogen exchange mass spectrometry at higher resolution with electron transfer dissociation Yuqi Shi1, Graeme McAlister1, Rosa Viner1, 1Thermo Fisher Scientific, San Jose, CA Abstract Results Purpose: Study protein, protein/complex conformations by…

TECHNICAL NOTE 65887 Hydrogen deuterium exchange mass spectrometry for protein structural characterization Authors: Terry Zhang and Rosa Viner Thermo Fisher Scientific, San Jose, CA, USA Keywords: Peptide mapping, protein conformation, bottom-up, deuterium uptake, hydrogen deuterium exchange mass spectrometry, HDX-MS, HDX,…

APPLICATION NOTE 65888 Structural characterization of the therapeutic antibody and biosimilar product with hydrogen deuterium exchange mass spectrometry Authors: Terry Zhang and Rosa Viner Thermo Fisher Scientific, San Jose, CA, USA Keywords: Peptide mapping, protein conformation, bottom-up, trastuzumab, biosimilar, deuterium…