Conformational Characterization of Calmodulin by Hydrogen Deuterium Exchange Mass Spectrometry

WHITE PAPER 65872 Hydrogen deuterium exchange mass spectrometry for the masses Executive summary Determining the shape and dynamics of proteins and protein complexes is crucial to understanding protein function and the roles proteins play in biological systems. Traditional techniques employed…

LOCALIZED CONFORMATION ANALYSES OF MUTATED HUMAN IgG1 BY HYDROGEN DEUTERIUM EXCHANGE MASS SPECTROMETRY AND DIFFERENTIAL SCANNING CALORIMETRY Joomi Ahn 1, Xiaojun Lu2, Colette Quinn3, St John Skilton1, Ying Qing Yu1, and Jihong Wang2 1 Waters Corporation, 2 MedImmune, 3TA Instruments…

Poster # P-I-0178 Probe the protein conformation using top-down hydrogen exchange mass spectrometry at higher resolution with electron transfer dissociation Yuqi Shi1, Graeme McAlister1, Rosa Viner1, 1Thermo Fisher Scientific, San Jose, CA Abstract Results Purpose: Study protein, protein/complex conformations by…

ACQUITY UPLC M-Class System with HDX Technology Integration of Hydrogen Deuterium Exchange with High Resolution MS QUANT IF Y CHANGES IN P ROT EIN CONFORMAT ION W IT H CONFIDENC E The Waters ® ACQUITY UPLC ® M-Class System with…