Robust, rapid SEC-MALS titer analysis of AAV particles using 3 μm, 550 Å monodisperse SEC media in bioinert column hardware

Comprehensive analysis of adeno-associated virus quality using 3 µm monodisperse Strong Anion Exchange and Size Exclusion chromatography columns Christof Mitterer1, Ke Ma2, Steven Milian3, Shane Bechler2 and Shanhua Lin2 1Thermo Fisher Scientific, Am Parir 20, 52379 Langerwehe, Germany - 2Thermo…

Application note | 003089 Biopharma Size-exclusion chromatography of adeno-associated viruses with the SurePac Bio 550 SEC MDi column Authors Key benefits Ke Ma1, Jessie Ashworth2, Victor Nieves2, • High-resolution separation of monomeric AAV and aggregates by size-exclusion liquid chromatography within…

HPLC columns Achieving consistent SEC performance through the use of 3 µm, 550 Å monodisperse media in novel bioinert column hardware Audrius Žvirblis1, Mauro De Pra2, Ke Ma3 1Thermo Fisher Scientific, Vilnius, Lithuania, 2 Thermo Fisher Scientific, Segrate, Italy, 3…

Application Note Heightened Characterization of AAVs by SEC-MALS with XBridge™ Premier GTx BEH™ SEC 450 Å 2.5 µm Columns Lavelay Kizekai, Balasubrahmanyam Addepalli, Matthew A. Lauber Waters Corporation For in vitro diagnostic use. Not available in all countries. Abstract Gene…