Comprehensive analysis of adeno-associated virus quality using 3 μm monodisperse Strong Anion Exchange and Size Exclusion chromatography columns

Robust, rapid SEC-MALS titer analysis of AAV particles using 3 µm, 550 Å monodisperse SEC media in bioinert column hardware Ke Ma1, Jessie Ashworth2, Victor Nieves2, Ashleigh Koontz1, Steven Milian2, Shane Bechler1 1Thermo Fisher Scientific, 1228 Titan Way, Sunnyvale, CA…

Application note | 001816 Biopharma Salt gradient separation and analysis of adeno-associated virus samples using a 3 μm monodisperse strong anion exchange chromatography column Authors Application benefits Ke Ma, Shane Bechler • High-resolution separation of empty and full AAV capsids…

ProPac™ 3R 3 μm IEX Separation and analysis of adeno-associated virus vectors using a 3 μm monodisperse strong anion exchange chromatography column Christof Mitterer1, Ke Ma2, Shane Bechler2, Shanhua Lin2. Thermo Fisher Scientific, 1 Langerwehe, Germany; 2 Sunnyvale, US Abstract…

Application note | 003089 Biopharma Size-exclusion chromatography of adeno-associated viruses with the SurePac Bio 550 SEC MDi column Authors Key benefits Ke Ma1, Jessie Ashworth2, Victor Nieves2, • High-resolution separation of monomeric AAV and aggregates by size-exclusion liquid chromatography within…