Heightened Characterization of AAVs by SEC-MALS with XBridge Premier GTx BEH SEC 450 Å 2.5 μm Columns

W H I T E PA P E R WP1618: Enhanced SEC-MALS analysis of therapeutic mAbs, biosimilars and AAVs with XBridge Premier columns Leo Liu, Ph.D., Waters | Wyatt Technology Summary SEC-MALS is widely used for the characterization of biopharmaceuticals.…

Application Note Improved SizeExclusion Chromatography of Adeno-Associated Viruses (AAVs) With XBridge™ Premier GTx BEH™ SEC 450 Å 2.5 µm Columns Mateusz Imiolek, Szabolcs Fekete, Matthew A. Lauber Waters Corporation Abstract This application note discusses the use of XBridge™ Premier GTx…

CONSUMABLES GUIDE BOOK Characterizing AAVs Chromatographic methods to measure heterogeneity and critical quality attributes CONSUMABLES GUIDE BOOK A Changing Industry Attribute Testing The advent of FDA approved gene therapies brings An AAV vectored therapy contains multiple types of biomolecules compromised…

A P P L I C AT I O N N O T E AN1617: Quantifying quality attributes of AAV gene therapy vectors by SEC-UV-MALS-dRI Michelle Chen, Ph.D. and Anatolii Purchel, Ph.D., Wyatt Technology Corporation Summary The adeno-associated virus (AAV)…