Applications from the field of Pharma & Biopharma focused on LC/Orbitrap - page 6

Open paper Thermo Scientific Stellar mass spectrometer

Thermo Scientific Stellar mass spectrometer

LC/MS, LC/MS/MS, LC/HRMS, LC/Orbitrap
Instrumentation
LC/MS, LC/MS/MS, LC/HRMS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Proteomics , Metabolomics, Lipidomics, Pharma & Biopharma
Open paper Optimizing Mass Spectrometer Conditions to Accurately Determine Full/Empty AAV Ratios: A Sample Half-Full Approach

Optimizing Mass Spectrometer Conditions to Accurately Determine Full/Empty AAV Ratios: A Sample Half-Full Approach

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper Method considerations for therapeutic ASO RNA analysis. Adducts and insource impurity generation

Method considerations for therapeutic ASO RNA analysis. Adducts and insource impurity generation

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper In-Depth Characterization of Monoclonal Antibodies Using Intact Mass Analysis and Middle-down Approaches on Orbitrap Ascend BioPharma Tribrid Mass Spectrometer

In-Depth Characterization of Monoclonal Antibodies Using Intact Mass Analysis and Middle-down Approaches on Orbitrap Ascend BioPharma Tribrid Mass Spectrometer

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper Oligonucleotide Workflow Incorporating Nuclease-Conjugated Beads with LC-MS/MS

Oligonucleotide Workflow Incorporating Nuclease-Conjugated Beads with LC-MS/MS

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper Applying UHPLC HRAM MS-MS/MS method to assess host cell protein clearance during the purification process development of therapeutic mAbs

Applying UHPLC HRAM MS-MS/MS method to assess host cell protein clearance during the purification process development of therapeutic mAbs

LC/MS, LC/MS/MS, LC/HRMS, LC/Orbitrap
Instrumentation
LC/MS, LC/MS/MS, LC/HRMS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma, Proteomics
Open paper Complete Characterization of Trastuzumab Deruxtecan, a Cysteine-linked antibody drug conjugate, using high resolution accurate mass (HRAM) Mass Spectrometry

Complete Characterization of Trastuzumab Deruxtecan, a Cysteine-linked antibody drug conjugate, using high resolution accurate mass (HRAM) Mass Spectrometry

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper Increased sensitivity and throughput for native intact mass analysis of mAb and ADCs using an online buffer exchange column

Increased sensitivity and throughput for native intact mass analysis of mAb and ADCs using an online buffer exchange column

LC/HRMS, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, Consumables
Instrumentation
LC/HRMS, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, Consumables
Manufacturer
Thermo Fisher Scientific
Industries
Proteomics , Pharma & Biopharma
Open paper Imaged capillary isoelectric focusing – Mass Spectrometry (iCIEF- MS) online coupling for polatuzumab vedotin charge heterogeneity analysis using native MS

Imaged capillary isoelectric focusing – Mass Spectrometry (iCIEF- MS) online coupling for polatuzumab vedotin charge heterogeneity analysis using native MS

LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper Performance evaluation of a new reversed-phase column for peptide mapping and monitoring of monoclonal antibodies

Performance evaluation of a new reversed-phase column for peptide mapping and monitoring of monoclonal antibodies

Consumables, LC columns, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
Consumables, LC columns, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma