Applications from the field of Pharma & Biopharma focused on LC/MS/MS - page 7

Open paper Workflows for GLP-1 Receptor Agonists and Therapeutic Peptides: Identity, Impurity, Bioanalysis, and Stability Testing

Workflows for GLP-1 Receptor Agonists and Therapeutic Peptides: Identity, Impurity, Bioanalysis, and Stability Testing

HPLC, LC/MS, RAMAN Spectroscopy, LC/SQ, LC/MS/MS, LC/TOF, LC/HRMS, LC/QQQ, UV–VIS spectrophotometry
Instrumentation
HPLC, LC/MS, RAMAN Spectroscopy, LC/SQ, LC/MS/MS, LC/TOF, LC/HRMS, LC/QQQ, UV–VIS spectrophotometry
Manufacturer
Agilent Technologies
Industries
Pharma & Biopharma, Clinical Research
Open paper LC-MS Analysis of Two mRNA Critical Quality Attributes: 5’-Capping Efficiency and Average Poly(A) Tail Length and Heterogeneity Using the Xevo™ MRT Mass Spectrometer

LC-MS Analysis of Two mRNA Critical Quality Attributes: 5’-Capping Efficiency and Average Poly(A) Tail Length and Heterogeneity Using the Xevo™ MRT Mass Spectrometer

LC/MS, LC/MS/MS, LC/HRMS, LC/TOF, Software
Instrumentation
LC/MS, LC/MS/MS, LC/HRMS, LC/TOF, Software
Manufacturer
Waters
Industries
Pharma & Biopharma
Open paper Multipass Ion Mobility Separation of GLP-1 Receptor Agonist Impurities Using the SELECT SERIES™ Cyclic™ IMS

Multipass Ion Mobility Separation of GLP-1 Receptor Agonist Impurities Using the SELECT SERIES™ Cyclic™ IMS

LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility
Instrumentation
LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility
Manufacturer
Waters
Industries
Pharma & Biopharma
Open paper Characterizing the Poly(A) tail in mRNA using Ion-Pairing Reversed-Phase LC/MS (IPRP-LC/MS) and Deconvolution Tools

Characterizing the Poly(A) tail in mRNA using Ion-Pairing Reversed-Phase LC/MS (IPRP-LC/MS) and Deconvolution Tools

LC/MS, LC/MS/MS, LC/TOF, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/TOF, LC/HRMS
Manufacturer
Agilent Technologies
Industries
Pharma & Biopharma
Open paper HRMS QTOF-PRM (Parallel reaction Monitoring) for ultra-trace level quantification of N-Nitroso Moxifloxacin in API and Formulations.

HRMS QTOF-PRM (Parallel reaction Monitoring) for ultra-trace level quantification of N-Nitroso Moxifloxacin in API and Formulations.

LC/MS, LC/MS/MS, LC/TOF, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/TOF, LC/HRMS
Manufacturer
Agilent Technologies
Industries
Pharma & Biopharma
Open paper LC-MS analysis of intact and subunit-level mAb enabled by a novel monodisperse supermacroporous reversed-phase platform

LC-MS analysis of intact and subunit-level mAb enabled by a novel monodisperse supermacroporous reversed-phase platform

LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper A switchable 2D-LC platform in PAT: routine UV monitoring or MS-based characterization of mAb PQAs directly from the bioreactor

A switchable 2D-LC platform in PAT: routine UV monitoring or MS-based characterization of mAb PQAs directly from the bioreactor

LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper Separating and Identifying Site-Specific Isomeric Amino Acids in GLP-1 Receptor Agonists on the Cyclic™ IMS P20 Mass Spectrometer

Separating and Identifying Site-Specific Isomeric Amino Acids in GLP-1 Receptor Agonists on the Cyclic™ IMS P20 Mass Spectrometer

LC/MS, LC/MS/MS, LC/TOF, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/TOF, LC/HRMS
Manufacturer
Waters
Industries
Pharma & Biopharma
Open paper Increasing Throughput in Collision-Induced Unfolding Studies: Enhancing Sensitivity and Streamlining Set-up

Increasing Throughput in Collision-Induced Unfolding Studies: Enhancing Sensitivity and Streamlining Set-up

LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility
Instrumentation
LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility
Manufacturer
Waters
Industries
Pharma & Biopharma
Open paper Characterizing Nucleic Acid Payloads in Lipid Nanoparticles and Viral Vectors via Charge Detection Mass Spectrometry (CDMS)

Characterizing Nucleic Acid Payloads in Lipid Nanoparticles and Viral Vectors via Charge Detection Mass Spectrometry (CDMS)

LC/MS, LC/MS/MS, LC/IT, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/IT, LC/HRMS
Manufacturer
Waters
Industries
Pharma & Biopharma, Lipidomics