Applications from the field of Pharma & Biopharma focused on LC/MS/MS - page 1

Open paper Development of timsMRMS: A Gated-TIMS FT-ICR MS instrument to decipher isomeric content of complex organic mixtures

Development of timsMRMS: A Gated-TIMS FT-ICR MS instrument to decipher isomeric content of complex organic mixtures

LC/MS, LC/MS/MS, Ion Mobility, LC/Ultra-HRMS, MALDI, MS Imaging
Instrumentation
LC/MS, LC/MS/MS, Ion Mobility, LC/Ultra-HRMS, MALDI, MS Imaging
Manufacturer
Bruker
Industries
Pharma & Biopharma
Open paper Rapid Quantification of Clinically Relevant Compound Classes by Chromatography-Free DART-MS/MS

Rapid Quantification of Clinically Relevant Compound Classes by Chromatography-Free DART-MS/MS

LC/MS, LC/MS/MS, DART, LC/QQQ
Instrumentation
LC/MS, LC/MS/MS, DART, LC/QQQ
Manufacturer
Bruker
Industries
Clinical Research, Pharma & Biopharma
Open paper MSⁿ Characterization of Chemical Modifications in Pharmaceutical Protein Byproducts Using the timsOmni Platform

MSⁿ Characterization of Chemical Modifications in Pharmaceutical Protein Byproducts Using the timsOmni Platform

LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility
Instrumentation
LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility
Manufacturer
Bruker
Industries
Pharma & Biopharma, Proteomics
Open paper Top-down sequencing of bispecific antibodies by electron capture dissociation on a timsOmni platform

Top-down sequencing of bispecific antibodies by electron capture dissociation on a timsOmni platform

LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility
Instrumentation
LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility
Manufacturer
Bruker
Industries
Pharma & Biopharma
Open paper Top‐Down Mapping of Protein Modifications by Multimodal MSⁿ on the New timsOmni Platform

Top‐Down Mapping of Protein Modifications by Multimodal MSⁿ on the New timsOmni Platform

LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility, Software
Instrumentation
LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility, Software
Manufacturer
Bruker
Industries
Pharma & Biopharma
Open paper Applying cDDA-eXd on a timsOmni to the analysis of the Fab regions of antibodies originating from human serum

Applying cDDA-eXd on a timsOmni to the analysis of the Fab regions of antibodies originating from human serum

LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility
Instrumentation
LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility
Manufacturer
Bruker
Industries
Pharma & Biopharma
Open paper Offline tandem MSn workflows on the timsOmni platform for deep sequencing of intact proteins and mAbs

Offline tandem MSn workflows on the timsOmni platform for deep sequencing of intact proteins and mAbs

LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility, Software
Instrumentation
LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility, Software
Manufacturer
Bruker
Industries
Pharma & Biopharma
Open paper Advances in hardware design and function of the new timsOmni MS platform

Advances in hardware design and function of the new timsOmni MS platform

LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility
Instrumentation
LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility
Manufacturer
Bruker
Industries
Pharma & Biopharma
Open paper On-demand Online Reduction of Intact Antibodies for Automated Workflows on SampleStream coupled to a timsTOF

On-demand Online Reduction of Intact Antibodies for Automated Workflows on SampleStream coupled to a timsTOF

LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility
Instrumentation
LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, Ion Mobility
Manufacturer
Bruker
Industries
Pharma & Biopharma
Open paper Analysis of an Antibody-Drug Conjugate on a Novel Benchtop MALDI-TOF/TOF Platform

Analysis of an Antibody-Drug Conjugate on a Novel Benchtop MALDI-TOF/TOF Platform

LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, MALDI
Instrumentation
LC/MS, LC/MS/MS, LC/TOF, LC/HRMS, MALDI
Manufacturer
Bruker
Industries
Pharma & Biopharma