Applications from the field of Pharma & Biopharma focused on LC/MS/MS - page 1
Open paper LC-MS analysis of intact and subunit-level mAb enabled by a novel monodisperse supermacroporous reversed-phase platform
LC-MS analysis of intact and subunit-level mAb enabled by a novel monodisperse supermacroporous reversed-phase platform
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper A switchable 2D-LC platform in PAT: routine UV monitoring or MS-based characterization of mAb PQAs directly from the bioreactor
A switchable 2D-LC platform in PAT: routine UV monitoring or MS-based characterization of mAb PQAs directly from the bioreactor
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper dSEC and dSEC-HRMS Characterization of GLP-1a and Related Peptide Therapeutics
dSEC and dSEC-HRMS Characterization of GLP-1a and Related Peptide Therapeutics
GPC/SEC, LC/MS, LC/MS/MS, LC/HRMS, LC/TOF
Instrumentation
GPC/SEC, LC/MS, LC/MS/MS, LC/HRMS, LC/TOF
Manufacturer
Waters
Industries
Pharma & Biopharma
Open paper Sensitive LC-MS method for the quantitative analysis of semaglutide and liraglutide in human plasma
Sensitive LC-MS method for the quantitative analysis of semaglutide and liraglutide in human plasma
LC/MS, LC/MS/MS, LC/QQQ
Instrumentation
LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Thermo Fisher Scientific
Industries
Clinical Research, Pharma & Biopharma
Open paper Method transfer case study for instrument and LC column migration of the purification and analysis workflow for synthetic oligonucleotides
Method transfer case study for instrument and LC column migration of the purification and analysis workflow for synthetic oligonucleotides
Sample Preparation, HPLC, Consumables, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
Sample Preparation, HPLC, Consumables, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper High-sensitive multi-attribute analysis of ADCs under native conditions by using an online multiple heart-cut 2D-LC-HRAM mass spectrometry system
High-sensitive multi-attribute analysis of ADCs under native conditions by using an online multiple heart-cut 2D-LC-HRAM mass spectrometry system
2D-LC, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS, GPC/SEC
Instrumentation
2D-LC, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS, GPC/SEC
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper Green ion pair and HFIP free method for ASO RNA analysis with GLP compliant automated data handling
Green ion pair and HFIP free method for ASO RNA analysis with GLP compliant automated data handling
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper Detailed study into ASO impurity analysis, lessons learned, and myths dispelled while moving to compliant platform methods
Detailed study into ASO impurity analysis, lessons learned, and myths dispelled while moving to compliant platform methods
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper SBSE/SFE-SFC-MS/MS System to Analyze Migrating Plastic Additives in Medical Solutions and Biological Matrices
SBSE/SFE-SFC-MS/MS System to Analyze Migrating Plastic Additives in Medical Solutions and Biological Matrices
SFC, LC/MS, LC/MS/MS, LC/QQQ
Instrumentation
SFC, LC/MS, LC/MS/MS, LC/QQQ
Manufacturer
Shimadzu
Industries
Clinical Research, Pharma & Biopharma
Open paper Determination of Fatty Acids Composition in Polysorbates 80 and 20 Pharmaceutical Raw Materials by HPLC with Mass Detection
Determination of Fatty Acids Composition in Polysorbates 80 and 20 Pharmaceutical Raw Materials by HPLC with Mass Detection
LC/MS, LC/MS/MS, LC/TOF, LC/SQ
Instrumentation
LC/MS, LC/MS/MS, LC/TOF, LC/SQ
Manufacturer
Waters
Industries
Pharma & Biopharma
