Applications from the field of Pharma & Biopharma focused on LC/HRMS - page 1
Open paper LC-MS analysis of intact and subunit-level mAb enabled by a novel monodisperse supermacroporous reversed-phase platform
LC-MS analysis of intact and subunit-level mAb enabled by a novel monodisperse supermacroporous reversed-phase platform
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper A switchable 2D-LC platform in PAT: routine UV monitoring or MS-based characterization of mAb PQAs directly from the bioreactor
A switchable 2D-LC platform in PAT: routine UV monitoring or MS-based characterization of mAb PQAs directly from the bioreactor
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper dSEC and dSEC-HRMS Characterization of GLP-1a and Related Peptide Therapeutics
dSEC and dSEC-HRMS Characterization of GLP-1a and Related Peptide Therapeutics
GPC/SEC, LC/MS, LC/MS/MS, LC/HRMS, LC/TOF
Instrumentation
GPC/SEC, LC/MS, LC/MS/MS, LC/HRMS, LC/TOF
Manufacturer
Waters
Industries
Pharma & Biopharma
Open paper Method transfer case study for instrument and LC column migration of the purification and analysis workflow for synthetic oligonucleotides
Method transfer case study for instrument and LC column migration of the purification and analysis workflow for synthetic oligonucleotides
Sample Preparation, HPLC, Consumables, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
Sample Preparation, HPLC, Consumables, LC columns, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper High-sensitive multi-attribute analysis of ADCs under native conditions by using an online multiple heart-cut 2D-LC-HRAM mass spectrometry system
High-sensitive multi-attribute analysis of ADCs under native conditions by using an online multiple heart-cut 2D-LC-HRAM mass spectrometry system
2D-LC, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS, GPC/SEC
Instrumentation
2D-LC, LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS, GPC/SEC
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper Green ion pair and HFIP free method for ASO RNA analysis with GLP compliant automated data handling
Green ion pair and HFIP free method for ASO RNA analysis with GLP compliant automated data handling
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper Detailed study into ASO impurity analysis, lessons learned, and myths dispelled while moving to compliant platform methods
Detailed study into ASO impurity analysis, lessons learned, and myths dispelled while moving to compliant platform methods
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Instrumentation
LC/MS, LC/MS/MS, LC/Orbitrap, LC/HRMS
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper Performance evaluation of a new reversed-phase column for peptide mapping and monitoring of monoclonal antibodies
Performance evaluation of a new reversed-phase column for peptide mapping and monitoring of monoclonal antibodies
Consumables, LC columns, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
Consumables, LC columns, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper A novel approach for multiple PQAs monitoring of mAbs from bioreactors using 2D-LC-MS
A novel approach for multiple PQAs monitoring of mAbs from bioreactors using 2D-LC-MS
2D-LC, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
2D-LC, LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
Open paper Myth busting: “You cannot sequence oligonucleotides over 20 to 30 nucleotides long by LCMS/MS” Learn how to routinely sequence 100 nt oligonucleotides
Myth busting: “You cannot sequence oligonucleotides over 20 to 30 nucleotides long by LCMS/MS” Learn how to routinely sequence 100 nt oligonucleotides
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Instrumentation
LC/HRMS, LC/MS, LC/MS/MS, LC/Orbitrap
Manufacturer
Thermo Fisher Scientific
Industries
Pharma & Biopharma
