Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 14th September 2026? Check out new documents from the field of spectroscopy/spectrometry and related techniques!<blockquote>👉 <a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library">SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</a></blockquote><blockquote>👉 Need info about different analytical techniques? Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library">LabRulezLCMS</a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library">LabRulezGCMS</a> libraries.</blockquote>This week we bring you technical note by Agilent Technologies, application notes by Metrohm and Thermo Fisher Scientific and poster by Shimadzu / AOAC!<h3>1. Agilent Technologies: Transitioning from the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=10&amp;search=Cary+630">Agilent Cary 630 FTIR</a> to the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=10&amp;search=Cary+635">Agilent Cary 635 FTIR Spectrometer</a></h3>Demonstrating methodology equivalence for pharmaceutical applications<ul><li>Technical note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/te_cary_630_ftir_transition_cary_635_ftir_5994_9408en_agilent_a2ea2ce512.pdf">Full PDF for download</a>&nbsp;</li></ul>Fourier transform infrared (FTIR) spectroscopy is a powerful analytical tool used to analyze a wide variety of materials by interpreting their infrared (IR) wavenumber absorptions. Within pharmaceutical and biopharmaceutical industries, FTIR analysis is integral for material identification and quality assurance of pharmaceutical&nbsp;substances.&nbsp;In the pharmaceutical industry, the Agilent Cary 630 FTIR is used for the identification of drug products, incoming goods, and packaging materials, as specified in global pharmacopoeias, and provides quantitative information such as the concentration of components within pharmaceutical formulations.&nbsp;Agilent now presents the Cary 635 FTIR spectrometer—an ultracompact, easy-to-use, high-performing, portable FTIR system. With greater IR power, the Cary 635 FTIR features greater detection sensitivity and faster scanning times. With its predecessor's modular design, the Cary 635 FTIR can analyze the same samples with a newly enhanced performance quality and efficiency.&nbsp;For users in the pharmaceutical industry who have experience with the Cary 630 FTIR, this technical overview demonstrates the common methodologies and workflows between the Cary 635 FTIR and Cary 630 FTIR spectrometers for pharmaceutical purposes. It will compare the ability of the two instruments to measure and label IR spectra, identify relevant compounds such as active pharmaceutical ingredients (APIs), and quantify substances within commercial&nbsp;formulations.<h4>Instrumentation and software&nbsp;</h4>For comparison, all three application tests were conducted using the Cary 630 FTIR and Cary 635 FTIR spectrometers with ZnSe optics and equipped with a single-reflection diamond attenuated total reflectance (ATR) accessory. The specific method parameters are outlined within each corresponding application. Both the Cary 635 FTIR and Cary 630 FTIR use Agilent MicroLab software, which provides step-by-step instructions with supporting images to guide users through the entire analytical workflow. Both spectrometers follow the same methods and operational procedures from sample loading to data processing (Figure 1). Results are presented in an easy-to-understand, color-coded format with customizable limits, ensuring a rapid and intuitive data review.<h4>Conclusion&nbsp;</h4>The comparison presented here of both the Agilent Cary 635 FTIR and Cary 630 FTIR spectrometers demonstrated shared methodologies that produced consistent results across key applications within pharmacopoeia, including spectrum production, compound identification, and substance&nbsp;quantification. Featuring the same modularity, robustness, and ease of use as the Cary 630 FTIR, the Cary 635 FTIR also offers greater sensitivity and signal-to-noise ratio, resulting from an enhanced IR source intensity. Therefore, users operating in regulated environments can confidently upgrade to the Cary 635 FTIR with the understanding that the workflow from the Cary 630 FTIR is directly transferrable, and that their routine analyses will remain consistent and reliable.<h3>2. Metrohm: Coconut water analysis by NIRS</h3>Determination of Brix, salinity, conductivity, and pH with one instrument<ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/an_nir_145_download_05589da42d.pdf">Full PDF for download</a></li></ul>Fresh coconut water is the main edible part of the coconut (aside from the coconut meat) and has gained popularity as a health drink in recent years. Multiple factors influence the quality, such as harvesting time, growth location, and storage duration. This poses a challenge for industrial producers to achieve and maintain the desired product quality.&nbsp;Testing the properties of coconut water with standard laboratory methods can be challenging, since trained lab personnel are needed. In contrast, near-infrared spectroscopy (NIRS) is fast, chemical-free, and does not require sample preparation. This Application Note explains how NIRS is used for the multiparameter analysis of coconut water. The NIRS solution is easy to use and can be implemented either atline or in a quality control lab.<h4>EXPERIMENTAL EQUIPMENT&nbsp;</h4>An <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=220&amp;search=OMNIS+NIR">OMNIS NIR Analyzer </a>Liquid with a 1 mm flowthrough cell (Figure 1) was used to analyze 206 coconut samples from a commercial supplier. In this configuration, a peristaltic pump injects the sample into the flow-through cell, which is inserted into the cuvette holder. The cell is rinsed with water after each measurement.<h4>CONCLUSION</h4>This Application Note shows the feasibility of using NIR spectroscopy for the quality control of coconut water. The parameters Brix, conductivity, turbidity, pH value, and salinity can be monitored by NIRS in seconds without any sample preparation. The presented setup with a flow-through cell not only simplifies sample handling but also allows full automation when using an OMNIS Sample Robot. In addition to coconut water, the coconut fruit itself can also be analyzed using near-infrared spectroscopy.<h3>3. Shimadzu / AOAC: Analysis of Heavy Metals in Baby Food Using ICP-MS</h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/aoac_2026_46_d9c14b32e0.pdf">Full PDF for download</a></li></ul>Babies are more vulnerable to the effects of toxic metals, and baby food therefore requires careful testing. US and EU regulations1)–3) set limits for toxic metals in baby food. This study analyzed five baby foods using the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=1&amp;search=ICPMS-2040%2F2050">ICPMS-2040/2050</a> and evaluated spike recovery and long-term stability.<h4>Conclusion&nbsp;</h4>Elemental analysis of baby food was conducted using ICP-MS.&nbsp;We achieved detection limits that met stringent standards. The spike recovery tests provided good results for all samples with different matrices, confirming the validity of the analysis. Additionally, we analyzed 50 samples of infant formula with a high matrix approximately six hours and confirmed good stability.<h3>4. Thermo Fisher Scientific: Process Raman as a comprehensive solution for downstream buffer workflow</h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/process_raman_as_comprehensive_solution_an1440_en_c8049b8ede.pdf">Full PDF for download</a></li></ul>Raman technology is rapidly gaining interest as a promising Process Analytical Technology (PAT) solution for real-time, non-invasive monitoring and control of downstream biopharma processes, especially for therapeutics like monoclonal antibodies (mAbs) and nucleic acids. Raman measurement, based on the vibration of molecular bonds, is highly specific for identification and quantification, even in complex or interfering matrices.&nbsp;As an in-line PAT tool, Raman spectroscopy offers direct and rapid measurement in aqueous phases without sample preparation. These features make it ideal for monitoring and controlling dynamic processes such as downstream processing.This study demonstrates a real-time methodology for accurately quantifying formulation excipients in the dynamic ultrafiltration/diafiltration (UF/DF) process using the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2233">Thermo Scientific™ MarqMetrix™ All-In-One Process Raman Analyzer</a> (Figure 1). In addition, this study also illustrates a case where process Raman was able to provide real-time information on buffer quality.<h4>Results&nbsp;</h4>The Partial Least Squares (PLS) models for L-histidine, L-arginine, and sucrose were initially tested using seven independent samples collected on three different process Raman analyzers. Data were mathematically processed to standardize spectra across instruments before applying the models. All the spectra were interpolated to have a common x-axis by equally spacing the 2048 pixels across 60 to 3250 cm-1 Raman shift, followed by relative y-axis standardization using the SRM fluorescence data as described in the NIST standardization protocol.² Figure&nbsp;3 shows the correlation plot of predicted versus reference values for L-histidine, L-arginine, and sucrose for the validation samples. A correlation coefficient of over 95% and a root means square error (RMSE) of less than 5% of the reference value for calibration, cross-validation, and prediction across three instruments demonstrate the reliability of process Raman to accurately predict the concentrations of these excipients, as well as easy model transferability.<h4>Conclusion</h4>This work, combined with our previous demonstrations of accurate in-line protein quantification during UF/DF processes,⁷, ⁸ clearly highlights the value of process Raman for downstream process monitoring. Raman spectroscopy allows for the simultaneous measurement of multiple critical process parameters (CPPs) with a single scan. These findings establish process Raman as a PAT tool with unparalleled benefits compared to other analytical methods.&nbsp;Simultaneous measurement of protein and excipient concentrations not only allows tighter process control but also opens opportunities for automating downstream processing.&nbsp;The ability of process Raman to provide real-time insights into buffer quality before its use in UF/DF runs offers substantial value by preventing batch failures. This capability enhances quality control, making Raman spectroscopy an essential tool for integration as an in-line sensor to improve downstream process monitoring, control, and automation.

News from LabRulezICPMS Library - Week 38, 2026

In the week from September 21, the following webinars await you in the field of atomic and molecular spectroscopy and spectrometry<blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinars">👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</a></h4>👉 Search and filter in the largest global database with over 6 000 GC, LC, MS and spectroscopy webinars.</blockquote><h5>1. Malvern Panalytical: Unlocking the Solid Form: XRD Solutions for Pharmaceutical Development and Manufacturing</h5><ul><li>Tu, 22.9.2026 10:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6555">Registration</a></li></ul>Discover how X-ray diffraction (XRD) supports pharmaceutical development by characterizing polymorphism, crystal structure, crystallinity, and amorphous content from API development to QC.<h5>2. Bruker: XFlash® FlatQUAD 2L: Step Into The Future of SEM Elemental Analysis</h5><ul><li>Tu, 22.9.2026 10:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6516">Registration</a></li></ul>Discover a new detector for SEM elemental analysis and learn how XFlash® FlatQUAD 2L can accelerate elemental analysis and imaging of sensitive samples.<h5>3. Malvern Panalytical: Future Days: Catalysts, What Will Define the Next Decade of Catalysis?</h5><ul><li>Tu, 22.9.2026 15:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6553">Registration</a></li></ul>Explore the future of catalysis in hydrogen, CCUS, sustainable chemicals, and circular manufacturing, with expert insights on markets, standards, catalyst development, and advanced characterization.<h5>4. Bruker: Probing Structure, Ion Dynamics and Interfacial Reactivity in Energy-Storage Materials by Solid-State NMR</h5><ul><li>Tu, 22.9.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6515">Registration</a></li></ul>Learn how solid-state NMR reveals local structure, ion dynamics, and SEI interfacial behavior in energy-storage materials.<h5>5. Agilent Technologies: How to Perform Routine Quantification by FTIR: Tips &amp; Tricks Workshop</h5><ul><li>Tu, 22.9.2026 20:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6442">Registration</a></li></ul>Master routine FTIR quantification in this hands-on workshop. Learn how to use MicroLab and MicroLab Quant software to measure standards, build calibration curves, and analyze real-world samples.<h5>6. Agilent Technologies: Learn How FTIR Can Help You with Contamination and Poor Product Quality</h5><ul><li>Tu, 22.9.2026 21:30 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6441">Registration</a></li></ul>Discover how Agilent portable FTIR spectrometers enable fast, cost-effective contamination analysis with versatile sampling options to address product quality and equipment issues.<h5>7. Bruker: From Cleared Tissue to Quantitative 3D Insights: Integrated Bruker and Translucence Biosystems Workflows for Whole-Organ Imaging</h5><ul><li>We, 23.9.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6544">Registration</a></li></ul>Discover integrated Bruker and Translucence Biosystems workflows for 3D cleared tissue imaging and quantitative whole-organ light-sheet microscopy.<h5>8. SPECTRO Analytical Instruments: Automatic ICP-OES Analysis of Lubricating Oils Using SPECTRO GENESIS DSOI and ACAROS Automation</h5><ul><li>Th, 24.9.2026 10:30 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6527">Registration</a></li></ul>Learn how automated ICP-OES analysis of lubricating oils can accelerate quality control and wear metal monitoring workflows using SPECTRO GENESIS DSOI and ACAROS automation.<h5>9. Agilent Technologies: Detection and Identification of Microplastics in Water and Other Matrices Using the Agilent Laser Infrared Spectroscopy Microscope</h5><ul><li>Th, 24.9.2026 11:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6540">Registration</a></li></ul>Discover how the Agilent LDIR 8700 uses QCL-based infrared imaging to automate rapid microplastics analysis, data processing, and reporting while supporting current standards.<h5>10. Malvern Panalytical: From Sample to Reliable Result: How to Optimise Particle Concentration Measurements on the Zetasizer Advance</h5><ul><li>Th, 24.9.2026 14:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6557">Registration</a></li></ul>Learn how to optimize particle concentration measurements with the Zetasizer Advance, from sample preparation and parameter selection to data-quality checks and improved repeatability.<h5>11. Wiley: Image, analyze, and fabricate at the nanoscale: Advances in SEM and FIB SEM for quantum materials research</h5><ul><li>Th, 24.9.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6524">Registration</a></li></ul>Explore advances in SEM and FIB-SEM for quantum materials research and learn how these technologies support 3D characterization, nanoscale analysis, and nanodevice fabrication.<h5>12. Mettler-Toledo: Thermal Analysis of Thermoset Materials</h5><ul><li>Th, 24.9.2026 16:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/5777">Registration</a></li></ul>Explore the most important thermal properties of thermoset materials and learn how thermal analysis techniques can be used for their characterization.<h5>13. Agilent Technologies: Why fast, reliable trace-element analysis starts with triple-quad ICP-MS</h5><ul><li>Fr, 25.9.2026 17:30 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6547">Registration</a></li></ul>Discover how the Agilent 9500 triple-quadrupole ICP-MS accelerates trace-element analysis and helps eliminate spectral interferences for reliable results.

Webinars LabRulezICPMS Week 39/2026

Combining elemental analysis and molecular techniques to characterize Ancient Egyptian mummification balms

Article

Webinars

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Scientific article

Science and research

Poster

Everything from the world of analytical chemistry in one place. We connect people in solving their problems. At Labrulez you will find all the necessary information easily, quickly and clearly. Stop searching and start finding.

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Metrohm

Mettler-Toledo

Agilent Technologies

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SelectScience

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This discussion will go in depth into how the fully integrated Auto Dilution System (ADS 2) can streamline your ICP-MS workflow. Eliminate bottles and bottle necks by automating the creation of Calibration and QC standards as well as intelligent handling of unknown samples.
Join us to learn how the ADS 2 can streamline your day-to-day ICP-MS workflow and improve your lab efficiency.
<blockquote>
Presenter: Bert Woods (Application Scientist, Agilent Technologies, Inc.)
</blockquote>
<blockquote>
Joined the Agilent ICP-MS team in 2004, with previous employment in the semiconductor industry with Dominion Semiconductor (IBM/Toshiba) and Micron. Bert is a 1997 Chemistry graduate of Radford University in Virginia and an avid Washington DC Sports fan.
</blockquote>

Agilent Technologies: Productive Analysis of High Matrix Samples using ICP-MS with the Integrated Advanced Dilution System

Productive Analysis of High Matrix Samples using ICP-MS with the Integrated Advanced Dilution System

This discussion will go in depth into how the fully integrated Auto Dilution System (ADS 2) can streamline your ICP-MS workflow. 

ICP-MS with the Integrated Advanced Dilution System

<ul>
<li>Overview of conventional DSC technology and molecular reorganization</li>
<li>Introduction to the Flash DSC and the novel chip sensor</li>
<li>Metastable materials</li>
<li>Flash DSC basic principles</li>
<li>Flash DSC application examples</li>
</ul>
In many technical processes, material behaviors depend on the applied heating or cooling rates. For example, when investigating crystallization behavior that occurs during the injection molding process, it is essential to replicate the heating rates experienced during the actual process. To perform such experiments, extremely high heating and cooling rates are required, which cannot be achieved using conventional DSC instruments. As a result, fast-scanning calorimetry was developed.
<h5>Fast-Scanning Calorimetry Using Flash DSC Technology</h5>
The Flash DSC uses innovative technology to perform fast-scanning calorimetry with ultra-high heating and cooling rates of up to 3,000,000 K per second, in the temperature range of -95 to +1000 °C. This allows measurements to be performed that are not possible using conventional DSC, often revealing hidden properties of a material. It is ideal for investigating rapid crystallization and reorganization behaviors.
Find out more about this fascinating technology in our live webinar. The presentation will conclude with a Q&amp;A, so don’t miss your chance to ask questions!
<blockquote>
Presenter: Nicolas Fedelich
</blockquote>
<blockquote>
With a background in chemical engineering, Nicolas joined METTLER TOLEDO in 2009 as an application specialist for Thermal Analysis. Before that, he gained expertise in different laboratories implementing, developing, and validating analytical methods in both the pharmaceutical and environmental fields. Nicolas also worked for three years in the field carrying out on-site customer training and providing expert thermal analysis application support. In his present position, Nicolas expertly uses, teaches, and supports DSC, TGA, TMA, and DMA instruments at the METTLER TOLEDO head office in Switzerland.
</blockquote>

METTLER TOLEDO: The Exciting World of Flash DSC 

The Exciting World of Flash DSC

Advanced Material Characterization by Fast-Scanning Calorimetry

Aquaporin (AQP) water channels facilitate water diffusion across lipid bilayers following an osmotic gradient. AQPs are especially important in renal water reabsorption. AQP2 in the renal collecting duct mediates fine-tuning of urine volume in response to the antidiuretic hormone arginine vasopressin (AVP).
AVP mediates plasma membrane insertion of AQP2 from an intracellular reservoir of AQP2 containing vesicles, which instantly increases water reabsorption and urine concentration. The vesicle population cannot be resolved via conventional fluorescent microscopy, therefore detailed information regarding the AQP2 vesicular population is still lacking.
Expansion microscopy (ExM) addresses challenges in resolving vesicle populations. Newly established 4.5x ExM can increase resolution to 60–70 nm. In this webinar, Dr. Lene Niemann Nejsum, Professor of Epithelial Physiology and Pathophysiology at Aarhus University, will present results showing that 4.5 ExM is an ideal approach to obtain detailed information regarding the AQP2 vesicle population. Using 4.5x ExM, spinning disk microscopy and image processing, Dr. Nejsum and her team detected AQP2 vesicles/endosomes. Using different markers of the endosomal system, they obtained detailed information of the cellular AQP2 shuttling itinerary.
Key learning objectives
<ul>
<li>Understand how Aquaporin mediated water transport across lipid bilayers</li>
<li>Gain insight into Studies of intracellular vesicles using Expansion Microscopy</li>
<li>Learn more about the Use of Andor BC43 with Deconvolution for ExM</li>
</ul>
Who should attend?
Both new and experienced Imaris and BC43 users interested in accelerating microscopy projects. The research is relevant across life science projects where visualizsation and analysis is required.
Certificate of attendance
All webinar participants can request a certificate of attendance, including a learning outcomes summary, for continuing education purposes.
<blockquote>
Presenter: Geraint Wilde (Business Manager - Life Science Microscopy, Oxford Instruments Andor)
</blockquote>
<blockquote>
Dr. Geraint Wilde attained a Ph.D. in Neuroscience in 1997 from the University of Southampton, UK, before holding a number of research positions. He focused on intracellular signalling and gene expression through live-cell imaging. Dr. Wilde eventually pursued a commercial career in microscopy and he joined Andor Technology in 2009, where he is now Product Manager for Microscopy Solutions.
</blockquote>
<blockquote>
Presenter: Dr. Lene Niemann Nejsum (Professor of Epithelial Physiology and Pathophysiology, Department of Clinical Medicine, Aarhus University)
</blockquote>
<blockquote>
Dr. Lene Niemann Nejsum is a Professor of Epithelial Physiology and Pathophysiology at Aarhus University, Denmark. She earned her PhD in Medicine in 2004, followed by a five-year postdoctoral position at Stanford University, and completed a Doctor medicinae in 2023 from Aarhus University. Her research focuses on epithelial function and aquaporin (AQP) water channels. Her lab investigates the AQP2 vesicle population in renal cells using advanced microscopy, achieving the first visualization of their 3D network. Additionally, her lab has discovered novel AQP functions in cellular morphology, adhesion, migration, and polarity—key mechanisms in cancer development and progression.
</blockquote>

SelectScience: The Cellular Itinerary of Renal Aquaporin-2 Shuttling with 4.5x Expansion Microscopy

The Cellular Itinerary of Renal Aquaporin-2 Shuttling with 4.5x Expansion Microscopy

Results showing that newly established 4.5 expansion microscopy is an ideal approach to obtain detailed information regarding the AQP2 vesicle population.

Renal Aquaporin-2 Shuttling with 4.5x Expansion Microscopy

Don’t want the complexity of a valve system for your ICP?
Come along to this webinar where you can find out how StepAhead can help you get analysis done quicker and save money!
<blockquote>
Presenter: Matthew Gregory (Applications Specialist, TEA, Thermo Fisher Scientific)
</blockquote>
<blockquote>
After graduating from the University of Surrey with an MChem in Chemistry, Matthew has gained 20 years’ experience of trace elemental analysis in industry, working in environmental and precious metal research laboratories. In 2018, Matthew joined Thermo Fisher Scientific as an Applications Specialist for the Trace Elemental Analysis product range in the UK and Ireland.
</blockquote>
<blockquote>
Presenter: David Fishwick (Applications Specialist, TEA, Thermo Fisher Scientific)
</blockquote>
<blockquote>
David joined Thermo in 2022 as an Applications Specialist for the Trace Elemental Analysis product range in the UK and Ireland. Prior to joining Thermo, David has gained experience of trace elemental analysis and chromatography in industry, working in GMP, GLP and UKAS accrediated R&amp;D and pharmaceutical laboratories. David holds a BSc in Chemistry from Bangor University. 
</blockquote>

Thermo Scientific: Increasing Lab Productivity with Thermo Scientific iSC-65 with StepAhead for ICP

Increasing Lab Productivity with Thermo Scientific iSC-65 with StepAhead for ICP

Find out how StepAhead can help you get analysis done quicker and save money!

Increasing Lab Productivity with Thermo Scientific iSC-65

Elemental impurities are trace metals or elements that can be present in pharmaceuticals, impacting product safety and efficacy.
USP General Chapter &lt;232&gt; provides guidelines for controlling elemental impurities in pharmaceuticals, ensuring they meet acceptable levels for human consumption. Compliance with USP &lt;232&gt; is crucial for regulatory approval and maintaining product quality and safety.
Register to attend this Webinar and learn:
<ul>
<li>Elemental impurities as per USP 232/USP 233 and ICHQ3D
</li>
<li>Dive into the innovation that powers USP-232 guidelines
</li>
<li>Agilent&#39;s MH software with Agilent&#39;s complete workflow solutions
</li>
<li>Basic maintenance and early maintenance feedback of ICP-MS
</li>
</ul>
<blockquote>
Presenter: Dr. Kuldeep Sharma (Sales Development Manager - Pharma, Agilent Technologies)
</blockquote>
<blockquote>
Kuldeep Sharma has over 19 years of experience in area/s of Bioanalytical research, Drug metabolism &amp; pharmacokinetics and Pharma regulatory compliance. He has accomplished PhD in Biotechnology. His professional journey covers over 12 years in Analytical research (associated with R&amp;D’s of Zydus Cadila, Lambda, Pliva and Jubilant Biosys) and last 7 years in analytical instruments sales, marketing &amp; business development. With over 21 research articles published in international Journals, He presents convention of continues learning.
</blockquote>
<blockquote>
Presenter: Mr. Radhey Shyam (Application Specialist - Spectroscopy, Agilent Technologies)
</blockquote>
<blockquote>
Radhey Shyam is an Application Scientist responsible for Elemental Spectroscopy Solutions at Agilent Technologies at Centre of Excellence (COE) Lab, Manesar. He has been assisting in the development of new methods and applications, as well as providing training and educational activities for customers across various sectors on spectroscopy solutions and technologies for the past 10+ years. He has authored several publications in international journals. In addition, he has also contributed to global application and solution notes from Agilent, with a focus on spectroscopy Market.&quot;
</blockquote>
<blockquote>
Presenter: Mr. Ankush Sharma (Regional Marketing Program Manager- APAC (Pharma &amp; Biopharma), Agilent Technologies)
</blockquote>
<blockquote>
Ankush Sharma is a seasoned professional with over 12 years of extensive experience in sales and marketing across the pharmaceutical and biopharmaceutical sectors. His professional journey commenced with a strong educational foundation, earning a Master&#39;s degree in Biotechnology. Building upon this knowledge, he furthered his academic pursuits by obtaining a Master&#39;s in Business Administration with a specialization in Sales and Marketing, demonstrating his commitment to blending scientific understanding with strategic business acumen. For the past five years, he has been an integral part of Agilent, serving as the Regional Marketing Program Manager for the India and now Asia-Pacific (APAC) region for Pharma and Biopharma Markets.
</blockquote>

Agilent Technologies: Demystifying USP & ICHQ3D Guidelines for Elemental Impurities

Demystifying USP & ICHQ3D Guidelines for Elemental Impurities

Elemental impurities as per USP 232/USP 233 and ICHQ3D.

Demystifying USP & ICHQ3D Guidelines for Elemental Impuritie

Isotope fingerprints of nitrogen, carbon and sulfur are a powerful tool to interpret the diet, movement, and mobility of populations in archaeology and ecology studies. Typical sample materials are bone collagen or dentine. The challenge for sequential δ15N, δ13C and δ34S analysis of such samples is driven by extremely low concentration of sulfur (typically &lt;0.3 weight % S), and the samples are often rare and size limited.
This presentation will describe how we have optimized our Thermo Scientific EA IsoLink System with the new High Performance Kit for sulfur analysis to allow for high precision and accuracy NCS analysis. 
Here we will focus on hardware optimization and instrument maintenance to reduce SO2 carry-over, and the High Sensitivity Method setup that allows for SO2 pre-concentration.
What you will learn:
<ul>
<li>Introduction to the elemental analyzer workflow</li>
<li>System hardware optimization via High Performance Kit for sulfur analysis</li>
<li>High Sensitivity Method setup for NCS analysis</li>
<li>Analysis setup and data evaluation using Thermo Scientific Qtegra ISDS Software</li>
<li>Maintenance procedures for the EA IsoLink IRMS system</li>
</ul>
Who should join:
<ul>
<li>Scientists and chemists interested in elemental analysis </li>
<li>Lab managers and analysts that have analytical challenges in CNS elemental analysis of collagen samples or similar</li>
<li>Research laboratories that want to learn about expending their analytical capabilities</li>
</ul>
Can&#39;t join at this time? Register anyway to receive a link to the recording to watch at your convenience
<blockquote>
Presenter: Dr. Meike Fischer (Product Specialist, EA-IRMS, Thermo Fisher Scientific)
</blockquote>
<blockquote>
After completing her PhD at the Max Planck Institute for Solar System Research, in collaboration with the Geoscience Center Göttingen, Germany, Meike joined Thermo Fisher Scientific, Bremen in 2021 as a Product Evaluation Specialist and supported development of the new software for gas IRMS – Thermo Scientific Qtegra ISDS Software. Since 2022 Meike has taken on a Product Specialist role focusing on elemental analyzer instrumentation and gas equilibration analysis, developing applications and methods for isotope analysis in a variety of fields.
</blockquote>

Thermo Fisher Scientific: Improved EA-IRMS NCS workflow for archaeology and ecology applications

Improved EA-IRMS NCS workflow for archaeology and ecology applications

Optimized Thermo Scientific EA IsoLink System with the new High Performance Kit for sulfur analysis to allow for high precision and accuracy NCS analysis.

EA-IRMS NCS for archaeology and ecology applications

X-ray emission spectroscopy (XES) has wide ranging element-selective chemical sensitivity to characterize valence, spin-state, ligand bonds, and more. New developments in laboratory XES instrumentation enable routine sample testing. In conjunction with laboratory X-ray absorption spectroscopy (XAS), the laboratory XES systems are finding wide ranging applications in environmental science, energy storage, and more.
In this session, we will highlight laboratory XES capabilities in two energy regimes: hard X-ray (4.5-20 keV) and tender X-ray (2-5 keV). Across these regimes, element-selective capabilities enable analysis of 3rd row transition metals, sulfur, phosphorus, and more. Join to learn more about the wide ranging capabilities and applications of X-ray emission spectroscopy.
Key Learning Objectives:
<ul>
<li>Introduction to X-ray Emission Spectroscopy and its unique capabilities for materials characterization.</li>
<li>Detailed look into example applications of laboratory XES.</li>
<li>Overview of new lab-scale XES instrumentation.</li>
<li>Understanding the process of conducting a laboratory XES measurement, including a real-time measurement demonstration.</li>
</ul>
Who Should Attend:
<ul>
<li>Research Scientists from Universities or Industries that routinely perform materials characterization.</li>
<li>Materials Characterization Lab Managers and Users interested in understanding new techniques.</li>
<li>Those interested in element-specific, non-destructive material analysis.</li>
</ul>
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Presenter: Dr. William Holden (CTO and Co-founder, easyXAFS)
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Presenter: Dr. Zachary Lebens-Higgins (Testing and R&amp;D Manager, easyXAFS)
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Presenter: Dr. Paul Aronstein (Applications Scientist, easyXAFS)
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Presenter: Melissa O&#39;Meara (Forensic Science Consultant, C&amp;EN Media Group)
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C&EN: Materials Characterization with Lab X-ray Emission Spectroscopy (XES)

Materials Characterization with Lab X-ray Emission Spectroscopy (XES)

We will highlight laboratory XES capabilities in two energy regimes: hard X-ray (4.5-20 keV) and tender X-ray (2-5 keV).

Lab X-ray Emission Spectroscopy (XES)

Near Infrared (NIR) spectroscopy is fast, non-destructive, and simple to use, making it an excellent choice for any QC laboratory. If you have not thought about it before, now is the perfect time to take a closer look. Why should you care?
Recent innovations make it easier to get started, deliver results even faster and make workflows more efficient.
In this webinar, we will be looking at some of these innovations. After a quick recap of the basics of NIR spectroscopy, Dr. Dave van Staveren and Dr. Nicolas Rühl will show features like automatic model development, precise temperature control at the sample, and more that literally bring good vibrations to the QC laboratory. The presenters use examples from the food, polymers, and petrochemical industries to illustrate the practical benefits of these innovations.
Join us on 5 September for an inspiring webinar!
Key learnings of this webinar:
<ul>
<li>The basic principles of NIR spectroscopy</li>
<li>How recent hardware and software innovations make NIRS easier to implement and use this technique in your daily lab work</li>
<li>Application examples from the food, chemical, and petrochemical industry</li>
</ul>
Who should attend?
Laboratory managers, QC managers, laboratory technicians.
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Presenter: Dr. Nicolas Rühl (Product Manager Spectroscopy, Metrohm AG, Herisau)
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<blockquote>
Dr. Nicolas Rühl is working in the Competence Center Spectroscopy since 2015. In this time, he has been in charge of developing the near-infrared (NIR) spectroscopy business at Metrohm. Nicolas has a Master in Business Administration and received his PhD in physical chemistry on single-molecule spectroscopy using Vis-NIR and Raman spectroscopy technologies.
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Presenter: Dr. Dave van Staveren (Head of Competence Center Spectroscopy, Metrohm International Headquarters)
</blockquote>
<blockquote>
Dr. Dave van Staveren completed his university graduate work in the area of bio-inorganic chemistry with a strong focus on various spectroscopic methods. He has held several positions in Product Management and has been in charge of NIR Product Management and Application Development at Metrohm since 2016.
</blockquote>

Metrohm: Latest Innovations in Near-Infrared Spectroscopy and how they can be a Game Changer for your Routine Analysis

Latest Innovations in Near-Infrared Spectroscopy and how they can be a Game Changer for your Routine Analysis

After a quick recap of the basics of NIR spectroscopy, we will show automatic model development, precise temperature control, and more.

Latest Innovations in Near-Infrared Spectroscopy

Join this exclusive webinar to discover advanced strategies for enhancing the quality of lentiviral (LV) vectors in cell therapy manufacturing.Quality defects in LV vectors can significantly affect the efficacy and safety of final cell therapies. Despite their critical importance, there has been minimal focus on controlling and monitoring the quality of LV vectors used in cell therapy manufacture. Of particular concern is the risk of ‘breakthrough expression’ of the transgene, leading to CAR expression in producer cells and on the surface of the LV particle.&nbsp;&nbsp;In this webinar, Lentitek will demonstrate how its promoter system is designed to significantly reduce breakthrough expression of the transgene in producer cells, maximizing the functional LV titer during anti-CD19 CAR vector production. Additionally, the webinar will showcase the Leprechaun platform from Unchained Labs, which promises precise identification and monitoring of CAR expression on the LV surface. This webinar is essential for professionals dedicated to improving quality and safety of cell therapies.<blockquote>Presenter: Dr. Alex Shephard (Market Manager, Cell Therapy, Unchained Labs)Presenter:&nbsp;Dr. Adam Inche (Founder &amp; CEO, Lentitek)</blockquote>

Unchained Labs: Preventing the danger of unwanted CAR expression during lentivirus production

Preventing the danger of unwanted CAR expression during lentivirus production

Join this exclusive webinar to discover advanced strategies for enhancing the quality of lentiviral (LV) vectors in cell therapy manufacturing. 

Preventing danger of unwanted CAR expression

<h5>The Problem</h5>Characterizing ADCs can feel like reinventing the wheel when methods aren’t flexible enough to keep up with high-throughput analysis of different antibody-drug combinations or reaction conditions. ADC characterization usually involves a combination of several HPLC methods, but HPLC often takes too long, requires too much sample, or needs too much optimization to work with every candidate.<h5>The Solution</h5>Stunner makes high-throughput reads on 2 μL of sample to gather three key datapoints on up to 96 ADCs at-a-time. Keep an eye on antibody concentration, check the drug-antibody ratio (DAR), and watch out for aggregation – all in only two minutes per sample.<h5>The Proof</h5>In this seminar, we’ll show how Stunner characterized 6 model ADCs created from 1 mAb and 3 payload/linker combinations reacted at 2 molar ratios. We’ll explain how Stunner’s Unmix algorithms break down UV/Vis absorbance spectra into their component parts to quantify total protein and drug payload. We’ll also show how flexible that analysis is when it is taught new user-created reference spectra.<blockquote>Presenter: Andree Mueller (Senior Product Manager for Aunty and Honeybun, Unchained Labs)Presenter:&nbsp;Kevin Lance, PhD (Director, Product Management, Unchained Labs)Kevin Lance directs product management and covers the Stunner portfolio globally at Unchained Labs. His expertise includes biophysical characterization of viral vectors, lipid nanoparticles, proteins, and nucleic acids. Prior to Unchained Labs, his research experience covered the fields of sustained antibody delivery and nanotechnology. He earned his Ph.D. in Bioengineering from the joint UC Berkeley – UCSF Bioengineering Graduate Program.</blockquote>

Unchained Labs: Lose the lag with high-throughput and flexible ADC analysis on Stunner

Lose the lag with high-throughput and flexible ADC analysis on Stunner

Learn how Stunner enables rapid ADC characterization—measuring concentration, DAR, and aggregation from 2 μL samples in minutes, across up to 96 ADCs.