<p><strong>Our Library never stops expanding. What are the most recent contributions to LabRulezICPMS Library in the week of 14th September 2026? Check out new documents from the field of spectroscopy/spectrometry and related techniques!</strong></p><blockquote><p><span style="font-size:20px;">👉 </span><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/library"><span style="font-size:20px;"><strong>SEARCH THE LARGEST REPOSITORY OF DOCUMENTS ABOUT SPECTROSCOPY/SPECTROMETRY RELATED TECHNIQUES</strong></span></a></p></blockquote><blockquote><p><strong>👉 Need info about different analytical techniques?</strong> Peek into <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/library"><strong>LabRulezLCMS</strong></a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/library"><strong>LabRulezGCMS</strong></a> libraries.</p></blockquote><p>This week we bring you technical note by <strong>Agilent Technologies, </strong>application notes by<strong> Metrohm </strong>and <strong>Thermo Fisher Scientific </strong>and poster by<strong> Shimadzu / AOAC!</strong></p><h3><strong>1. Agilent Technologies: Transitioning from the </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=10&amp;search=Cary+630"><strong>Agilent Cary 630 FTIR</strong></a><strong> to the </strong><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=10&amp;search=Cary+635"><strong>Agilent Cary 635 FTIR Spectrometer</strong></a></h3><p><strong>Demonstrating methodology equivalence for pharmaceutical applications</strong></p><ul><li>Technical note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/te_cary_630_ftir_transition_cary_635_ftir_5994_9408en_agilent_a2ea2ce512.pdf"><strong>Full PDF for download</strong></a><strong>&nbsp;</strong></li></ul><p>Fourier transform infrared (FTIR) spectroscopy is a powerful analytical tool used to analyze a wide variety of materials by interpreting their infrared (IR) wavenumber absorptions. Within pharmaceutical and biopharmaceutical industries, FTIR analysis is integral for material identification and quality assurance of pharmaceutical&nbsp;substances.&nbsp;</p><p>In the pharmaceutical industry, the Agilent Cary 630 FTIR is used for the identification of drug products, incoming goods, and packaging materials, as specified in global pharmacopoeias, and provides quantitative information such as the concentration of components within pharmaceutical formulations.&nbsp;</p><p>Agilent now presents the Cary 635 FTIR spectrometer—an ultracompact, easy-to-use, high-performing, portable FTIR system. With greater IR power, the Cary 635 FTIR features greater detection sensitivity and faster scanning times. With its predecessor's modular design, the Cary 635 FTIR can analyze the same samples with a newly enhanced performance quality and efficiency.&nbsp;</p><p>For users in the pharmaceutical industry who have experience with the Cary 630 FTIR, this technical overview demonstrates the common methodologies and workflows between the Cary 635 FTIR and Cary 630 FTIR spectrometers for pharmaceutical purposes. It will compare the ability of the two instruments to measure and label IR spectra, identify relevant compounds such as active pharmaceutical ingredients (APIs), and quantify substances within commercial&nbsp;formulations.</p><h4><strong>Instrumentation and software&nbsp;</strong></h4><p>For comparison, all three application tests were conducted using the Cary 630 FTIR and Cary 635 FTIR spectrometers with ZnSe optics and equipped with a single-reflection diamond attenuated total reflectance (ATR) accessory. The specific method parameters are outlined within each corresponding application. Both the Cary 635 FTIR and Cary 630 FTIR use Agilent MicroLab software, which provides step-by-step instructions with supporting images to guide users through the entire analytical workflow. Both spectrometers follow the same methods and operational procedures from sample loading to data processing (Figure 1). Results are presented in an easy-to-understand, color-coded format with customizable limits, ensuring a rapid and intuitive data review.</p><h4><strong>Conclusion&nbsp;</strong></h4><p>The comparison presented here of both the Agilent Cary 635 FTIR and Cary 630 FTIR spectrometers demonstrated shared methodologies that produced consistent results across key applications within pharmacopoeia, including spectrum production, compound identification, and substance&nbsp;quantification. Featuring the same modularity, robustness, and ease of use as the Cary 630 FTIR, the Cary 635 FTIR also offers greater sensitivity and signal-to-noise ratio, resulting from an enhanced IR source intensity. Therefore, users operating in regulated environments can confidently upgrade to the Cary 635 FTIR with the understanding that the workflow from the Cary 630 FTIR is directly transferrable, and that their routine analyses will remain consistent and reliable.</p><h3><strong>2. Metrohm: Coconut water analysis by NIRS</strong></h3><p><strong>Determination of Brix, salinity, conductivity, and pH with one instrument</strong></p><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/an_nir_145_download_05589da42d.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Fresh coconut water is the main edible part of the coconut (aside from the coconut meat) and has gained popularity as a health drink in recent years. Multiple factors influence the quality, such as harvesting time, growth location, and storage duration. This poses a challenge for industrial producers to achieve and maintain the desired product quality.&nbsp;</p><p>Testing the properties of coconut water with standard laboratory methods can be challenging, since trained lab personnel are needed. In contrast, near-infrared spectroscopy (NIRS) is fast, chemical-free, and does not require sample preparation. This Application Note explains how NIRS is used for the multiparameter analysis of coconut water. The NIRS solution is easy to use and can be implemented either atline or in a quality control lab.</p><h4><strong>EXPERIMENTAL EQUIPMENT&nbsp;</strong></h4><p>An <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=220&amp;search=OMNIS+NIR"><strong>OMNIS NIR Analyzer </strong></a>Liquid with a 1 mm flowthrough cell (Figure 1) was used to analyze 206 coconut samples from a commercial supplier. In this configuration, a peristaltic pump injects the sample into the flow-through cell, which is inserted into the cuvette holder. The cell is rinsed with water after each measurement.</p><h4><strong>CONCLUSION</strong></h4><p>This Application Note shows the feasibility of using NIR spectroscopy for the quality control of coconut water. The parameters Brix, conductivity, turbidity, pH value, and salinity can be monitored by NIRS in seconds without any sample preparation. The presented setup with a flow-through cell not only simplifies sample handling but also allows full automation when using an OMNIS Sample Robot. In addition to coconut water, the coconut fruit itself can also be analyzed using near-infrared spectroscopy.</p><h3><strong>3. Shimadzu / AOAC: Analysis of Heavy Metals in Baby Food Using ICP-MS</strong></h3><ul><li>Poster</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/aoac_2026_46_d9c14b32e0.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Babies are more vulnerable to the effects of toxic metals, and baby food therefore requires careful testing. US and EU regulations1)–3) set limits for toxic metals in baby food. This study analyzed five baby foods using the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/icpms/library?mainauthorItems=1&amp;search=ICPMS-2040%2F2050"><strong>ICPMS-2040/2050</strong></a> and evaluated spike recovery and long-term stability.</p><h4><strong>Conclusion&nbsp;</strong></h4><p>Elemental analysis of baby food was conducted using ICP-MS.&nbsp;</p><p>We achieved detection limits that met stringent standards. The spike recovery tests provided good results for all samples with different matrices, confirming the validity of the analysis. Additionally, we analyzed 50 samples of infant formula with a high matrix approximately six hours and confirmed good stability.</p><h3><strong>4. Thermo Fisher Scientific: Process Raman as a comprehensive solution for downstream buffer workflow</strong></h3><ul><li>Application note</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/pdf/process_raman_as_comprehensive_solution_an1440_en_c8049b8ede.pdf"><strong>Full PDF for download</strong></a></li></ul><p>Raman technology is rapidly gaining interest as a promising Process Analytical Technology (PAT) solution for real-time, non-invasive monitoring and control of downstream biopharma processes, especially for therapeutics like monoclonal antibodies (mAbs) and nucleic acids. Raman measurement, based on the vibration of molecular bonds, is highly specific for identification and quantification, even in complex or interfering matrices.&nbsp;</p><p>As an in-line PAT tool, Raman spectroscopy offers direct and rapid measurement in aqueous phases without sample preparation. These features make it ideal for monitoring and controlling dynamic processes such as downstream processing.</p><p>This study demonstrates a real-time methodology for accurately quantifying formulation excipients in the dynamic ultrafiltration/diafiltration (UF/DF) process using the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2233"><strong>Thermo Scientific™ MarqMetrix™ All-In-One Process Raman Analyzer</strong></a> (Figure 1). In addition, this study also illustrates a case where process Raman was able to provide real-time information on buffer quality.</p><h4><strong>Results&nbsp;</strong></h4><p>The Partial Least Squares (PLS) models for L-histidine, L-arginine, and sucrose were initially tested using seven independent samples collected on three different process Raman analyzers. Data were mathematically processed to standardize spectra across instruments before applying the models. All the spectra were interpolated to have a common x-axis by equally spacing the 2048 pixels across 60 to 3250 cm-1 Raman shift, followed by relative y-axis standardization using the SRM fluorescence data as described in the NIST standardization protocol.² Figure&nbsp;3 shows the correlation plot of predicted versus reference values for L-histidine, L-arginine, and sucrose for the validation samples. A correlation coefficient of over 95% and a root means square error (RMSE) of less than 5% of the reference value for calibration, cross-validation, and prediction across three instruments demonstrate the reliability of process Raman to accurately predict the concentrations of these excipients, as well as easy model transferability.</p><h4><strong>Conclusion</strong></h4><p>This work, combined with our previous demonstrations of accurate in-line protein quantification during UF/DF processes,⁷, ⁸ clearly highlights the value of process Raman for downstream process monitoring. Raman spectroscopy allows for the simultaneous measurement of multiple critical process parameters (CPPs) with a single scan. These findings establish process Raman as a PAT tool with unparalleled benefits compared to other analytical methods.&nbsp;</p><p>Simultaneous measurement of protein and excipient concentrations not only allows tighter process control but also opens opportunities for automating downstream processing.&nbsp;</p><p>The ability of process Raman to provide real-time insights into buffer quality before its use in UF/DF runs offers substantial value by preventing batch failures. This capability enhances quality control, making Raman spectroscopy an essential tool for integration as an in-line sensor to improve downstream process monitoring, control, and automation.</p>

News from LabRulezICPMS Library - Week 38, 2026

<p><strong>In the week from September 21, the following webinars await you in the field of atomic and molecular spectroscopy and spectrometry</strong></p><blockquote><h4><a target="_blank" rel="noopener noreferrer" href="https://icpms.labrulez.com/webinars"><strong>👉 DETAILS AND REGISTRATION IN THE WEBINARS SECTION</strong></a></h4><p><strong>👉 Search and filter in the largest global database</strong> with over <strong>6 000 GC, LC, MS and spectroscopy webinars</strong>.</p></blockquote><h5><strong>1. Malvern Panalytical: Unlocking the Solid Form: XRD Solutions for Pharmaceutical Development and Manufacturing</strong></h5><ul><li>Tu, 22.9.2026 10:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6555">Registration</a></li></ul><p>Discover how X-ray diffraction (XRD) supports pharmaceutical development by characterizing polymorphism, crystal structure, crystallinity, and amorphous content from API development to QC.</p><h5><strong>2. Bruker: XFlash® FlatQUAD 2L: Step Into The Future of SEM Elemental Analysis</strong></h5><ul><li>Tu, 22.9.2026 10:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6516">Registration</a></li></ul><p>Discover a new detector for SEM elemental analysis and learn how XFlash® FlatQUAD 2L can accelerate elemental analysis and imaging of sensitive samples.</p><h5><strong>3. Malvern Panalytical: Future Days: Catalysts, What Will Define the Next Decade of Catalysis?</strong></h5><ul><li>Tu, 22.9.2026 15:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6553">Registration</a></li></ul><p>Explore the future of catalysis in hydrogen, CCUS, sustainable chemicals, and circular manufacturing, with expert insights on markets, standards, catalyst development, and advanced characterization.</p><h5><strong>4. Bruker: Probing Structure, Ion Dynamics and Interfacial Reactivity in Energy-Storage Materials by Solid-State NMR</strong></h5><ul><li>Tu, 22.9.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6515">Registration</a></li></ul><p>Learn how solid-state NMR reveals local structure, ion dynamics, and SEI interfacial behavior in energy-storage materials.</p><h5><strong>5. Agilent Technologies: How to Perform Routine Quantification by FTIR: Tips &amp; Tricks Workshop</strong></h5><ul><li>Tu, 22.9.2026 20:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6442">Registration</a></li></ul><p>Master routine FTIR quantification in this hands-on workshop. Learn how to use MicroLab and MicroLab Quant software to measure standards, build calibration curves, and analyze real-world samples.</p><h5><strong>6. Agilent Technologies: Learn How FTIR Can Help You with Contamination and Poor Product Quality</strong></h5><ul><li>Tu, 22.9.2026 21:30 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6441">Registration</a></li></ul><p>Discover how Agilent portable FTIR spectrometers enable fast, cost-effective contamination analysis with versatile sampling options to address product quality and equipment issues.</p><h5><strong>7. Bruker: From Cleared Tissue to Quantitative 3D Insights: Integrated Bruker and Translucence Biosystems Workflows for Whole-Organ Imaging</strong></h5><ul><li>We, 23.9.2026 17:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6544">Registration</a></li></ul><p>Discover integrated Bruker and Translucence Biosystems workflows for 3D cleared tissue imaging and quantitative whole-organ light-sheet microscopy.</p><h5><strong>8. SPECTRO Analytical Instruments: Automatic ICP-OES Analysis of Lubricating Oils Using SPECTRO GENESIS DSOI and ACAROS Automation</strong></h5><ul><li>Th, 24.9.2026 10:30 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6527">Registration</a></li></ul><p>Learn how automated ICP-OES analysis of lubricating oils can accelerate quality control and wear metal monitoring workflows using SPECTRO GENESIS DSOI and ACAROS automation.</p><h5><strong>9. Agilent Technologies: Detection and Identification of Microplastics in Water and Other Matrices Using the Agilent Laser Infrared Spectroscopy Microscope</strong></h5><ul><li>Th, 24.9.2026 11:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6540">Registration</a></li></ul><p>Discover how the Agilent LDIR 8700 uses QCL-based infrared imaging to automate rapid microplastics analysis, data processing, and reporting while supporting current standards.</p><h5><strong>10. Malvern Panalytical: From Sample to Reliable Result: How to Optimise Particle Concentration Measurements on the Zetasizer Advance</strong></h5><ul><li>Th, 24.9.2026 14:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6557">Registration</a></li></ul><p>Learn how to optimize particle concentration measurements with the Zetasizer Advance, from sample preparation and parameter selection to data-quality checks and improved repeatability.</p><h5><strong>11. Wiley: Image, analyze, and fabricate at the nanoscale: Advances in SEM and FIB SEM for quantum materials research</strong></h5><ul><li>Th, 24.9.2026 16:00 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6524">Registration</a></li></ul><p>Explore advances in SEM and FIB-SEM for quantum materials research and learn how these technologies support 3D characterization, nanoscale analysis, and nanodevice fabrication.</p><h5><strong>12. Mettler-Toledo: Thermal Analysis of Thermoset Materials</strong></h5><ul><li>Th, 24.9.2026 16:00 CET</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/5777">Registration</a></li></ul><p>Explore the most important thermal properties of thermoset materials and learn how thermal analysis techniques can be used for their characterization.</p><h5><strong>13. Agilent Technologies: Why fast, reliable trace-element analysis starts with triple-quad ICP-MS</strong></h5><ul><li>Fr, 25.9.2026 17:30 CEST</li><li><a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/webinar/6547">Registration</a></li></ul><p>Discover how the Agilent 9500 triple-quadrupole ICP-MS accelerates trace-element analysis and helps eliminate spectral interferences for reliable results.</p>

Webinars LabRulezICPMS Week 39/2026

Combining elemental analysis and molecular techniques to characterize Ancient Egyptian mummification balms

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<p><strong>The Need for Half-Mass Measurement is real when running a single quad ICP-MS and with doubly charged interferences.</strong></p><p>ORS is very capable at the removal of polyatomic interferences under Helium Collision Mode; however, some samples contain high and variable levels of Rare Earth Elements (REE’s). REE’s that have relatively low second ionization potentials meaning they can form ions with a 2+ charge. Even at only 1% formation, if concentrations are high, the interferences can be significant enough. Let me show you how to set the half-mass measurement up in your software.</p><blockquote><p><strong>Presenter:</strong> Jenny Nelson, PhD (Application Scientist, Agilent Technologies, Inc).</p><p>Dr. Jenny Nelson is an Applications Scientist with Agilent Technologies specializing in Inductively Coupled Plasma Mass Spectroscopy (ICP-MS), Inductively Coupled Plasma Optical Emission Spectroscopy (ICP-OES), Microwave Plasma Atomic Emission Spectroscopy (MP-AES). Her broad knowledge of atomic spectroscopy has been applied to both AOAC and ASTM through her serving on expert review panels, chairing committees, and volunteering to develop new methods needed by the industry.</p><p><strong>Presenter: </strong>L. Craig Jones (ICP-MS Application Scientist, Agilent Technologies, Inc.)</p><p>Craig has been with Agilent for over 15 years as an ICP-MS applications scientist. He has been involved with multiple type of applications for ICP-MS, including environmental, pharmaceutical, semiconductor, geologic, and clinical analyses, to name a few. Previous to Agilent he worked in an environmental lab performing analysis and supervising both the inorganic and organic sections of the laboratory. In his spare time, Craig enjoys volunteering at the local marine science center, mountain biking, hiking, and relaxing at the beach. Craig obtained a Bachelor of Science degree in chemistry from Fort Lewis College in Durango, CO.</p></blockquote>

Agilent technologies: Avoiding Double Charged Interferences on Single Quadrupole ICP-MS

Avoiding Double Charged Interferences on Single Quadrupole ICP-MS

How to set the half-mass measurement up in your software.

Avoiding Double Charged Interferences on Single Quadrupole

<div><p><strong>This webinar will provide an overview of Chemical Exchange Saturation Transfer (CEST) MRI, from its physical principles and experimental design to the key factors influencing endogenous CEST signals in vivo. We will explore both physiological and technical sources of contrast, the complexity of in vivo CEST signals, and common artifacts such as fat contamination and field inhomogeneities.</strong></p><p>The session will also highlight essential correction strategies for achieving quantitative CEST MRI and showcase current applications in cancer and neuroimaging. Preclinical studies at ultra-high magnetic fields—such as the DKFZ’s 9.4 T Bruker system—play a key role in advancing methodological development, enabling a deeper understanding of complex CEST signal behavior in vivo and paving the way for clinical translation.</p><h5><strong>What to Expect</strong></h5><p>Join Dr. Philip S. Boyd for an in-depth exploration of Chemical Exchange Saturation Transfer (CEST) MRI, covering its theoretical foundations, practical implementation, and cutting-edge applications in cancer and neuroimaging. This webinar will guide attendees through the complexities of in vivo CEST signals, correction strategies for artifacts, and the translation of preclinical findings into clinical practice.</p><h5><strong>Key Learning Points</strong></h5><ul><li>Understanding the CEST Phenomenon and Theory</li><li>Applications in Cancer and Neuroimaging</li><li>Achieving Quantitative CEST imaging In Vivo</li></ul><h5><strong>Who should attend:</strong></h5><p>This webinar is ideal for researchers, clinicians, and imaging specialists working in MRI, oncology, neurology, or molecular imaging who are interested in advancing their understanding of quantitative CEST techniques and their translational potential. It will also be highly educational for graduate students and early-career scientists beginning their journey in MRI, offering foundational insights and practical guidance.</p><blockquote><p><strong>Presenter:</strong> Dr. Philip S. Boyd (Ph.D. in Physics from Heidelberg University and leads the CEST Imaging Group at the German Cancer Research Center (DKFZ) in Heidelberg)</p><p>Dr. Philip S. Boyd holds a Ph.D. in Physics from Heidelberg University and leads the CEST Imaging Group at the German Cancer Research Center (DKFZ) in Heidelberg. His research focuses on developing and refining advanced CEST imaging techniques, including pH imaging and fat artifact correction. He combines experimental imaging, mathematical modeling, and data analysis to drive CEST applications from preclinical research to clinical translation.</p></blockquote></div>

Bruker: Quantitative CEST MRI: From Principles to Applications in Cancer and Neuroimaging

Quantitative CEST MRI: From Principles to Applications in Cancer and Neuroimaging

Discover how CEST MRI works and how it's applied in cancer and neuroimaging. With insights from DKFZ’s cutting-edge preclinical studies.

Quantitative CEST MRI: From Theory to Clinical Insight

<div><p><strong>Batteries are central to the transition toward sustainable energy, but improving their performance, safety, and longevity demands a deep understanding of their chemical and physical processes. Nuclear Magnetic Resonance (NMR) and Electron Paramagnetic Resonance (EPR) spectroscopy are two complementary techniques that provide unmatched insights into the behavior of both electrodes and electrolytes at the molecular and atomic levels.</strong></p><p>This webinar will showcase how modern benchtop NMR and EPR instruments make these powerful techniques more accessible to researchers, enabling in-depth characterization directly in the laboratory. The session is structured around three presentations:</p><p>Benchtop NMR for electrolytes: an exploration of how NMR can be applied to study the composition, degradation, and dynamics of battery electrolytes.<br>Benchtop EPR for electrodes and electrolytes: an introduction to the unique information EPR reveals about paramagnetic species in battery components<br>Operando NMR and EPR for electrochemistry: an overview of the collaborative research with Radboud University demonstrating how combining these techniques together shed light on electrochemical processes, with a focus on redox flow batteries.</p><p>Through these presentations, you will learn how benchtop spectroscopy can help identify degradation pathways, monitor ion mobility, characterize electrode materials, and understand redox mechanisms in energy storage systems.</p><p>Whether you are investigating fundamental battery chemistry or optimizing materials for practical applications, this webinar will show you how benchtop NMR and EPR can be seamlessly integrated into your research. The speakers will share recent case studies, collaborative results, and practical considerations for applying these techniques effectively.</p><p>Join us to discover how accessible, high-quality spectroscopy at the benchtop can advance your battery research and contribute to the development of next-generation energy storage technologies.</p><h5><strong>What to Expect</strong></h5><ul><li>NMR for electrolyte analysis: composition, degradation &amp; dynamics</li><li>EPR for paramagnetic species in electrodes &amp; electrolytes</li><li>Operando NMR/EPR for electrochemistry: overview of collaborative research on redox flow batteries with Radboud University</li></ul><blockquote><p><strong>Presenter:</strong> Dr. Niels Karschin (Application Scientist, Bruker BioSpin)</p><p>Dr. Niels Karschin earned his Ph.D. developing NMR methods for structure characterization on both small molecules as well as proteins. He joined Bruker BioSpin as an Application Scientist in 2022, where he focuses on making advanced methods more accessible for routine users, particularly on benchtop systems.</p><p><strong>Presenter:</strong> Dr. Kalina Ranguelova (Senior EPR Applications Scientist, Bruker BioSpin)</p><p>Dr. Kalina Ranguelova has been an EPR Applications Scientist at Bruker BioSpin Corporation since 2011. She completed her Ph.D. at the Bulgarian Academy of Sciences, where her research focused on the structure of inorganic copper complexes using electron paramagnetic resonance (EPR) spectroscopy. After holding research positions at CUNY and the National Institute for Environmental Sciences, where she studied free radical biology and EPR spin trapping as a method for measuring reactive oxygen species (ROS), she joined Bruker. In her current role as an Applications Scientist, she focuses on developing new applications for EPR in various fields and providing customer support and training.</p><p><strong>Presenter:</strong> Giu Silva Testa (PhD Candidate at Magnetic Resonance Research Center)</p><p>Giu A. Silva Testa has been a PhD candidate at the Magnetic Resonance Research Center since July 2023, under the supervision of Dr. Evan Wenbo Zhao. Their research focuses on applying magnetic resonance techniques to explore the properties of Redox Flow Batteries (RFBs). To advance this research, Giu developed a novel dual benchtop NMR-EPR flow setup, which also has broader applications for studying other electrochemical systems. Giu holds a bachelor’s degree in Chemistry from the University of Barcelona (2016–2021) and a master’s degree in Physical Chemistry from Radboud University (2021–2023).&nbsp;</p></blockquote></div>

Bruker: Advancing Battery Research with Benchtop NMR and EPR

Advancing Battery Research with Benchtop NMR and EPR

Explore benchtop NMR and EPR for battery research. Gain insights into electrolytes, electrodes, and redox processes to improve energy storage performance.

<div><p><strong>Join us for an insightful webinar on the PIPAc project, an innovative approach to pharmaceutical manufacturing that integrates AI, NMR, flow chemistry, and 3D-printed modular reactors. Attendees will explore how AI-driven process control optimizes chemical reactions in real time, while in-line NMR provides precise monitoring of active pharmaceutical ingredient (API) synthesis. Continuous flow chemistry combined with compact, 3D-printed reactors enable mobile, resource-efficient production, supporting rapid scale-up and flexible deployment. Gain in-depth insights into the convergence of automation, analytical technologies, and advanced reactor design shaping modern pharmaceutical production.</strong></p><h5><strong>Key Learning Points</strong></h5><ul><li><strong>Enhanced Process Control: </strong>Learn how AI, NMR, and PAT enable real-time monitoring, optimizing reactions and ensuring efficient, reliable API production.</li><li><strong>Scalable and Flexible Production: </strong>Understand how modular 3D-printed reactors and continuous flow chemistry support rapid scale-up and mobile manufacturing.</li><li><strong>Innovative Applications:</strong> Explore advanced applications of flow chemistry, 3D-printed reactors, and AI-driven analytics to drive innovation and improve pharmaceutical API processes.</li></ul><h5><strong>What to Expect</strong></h5><p>Discover how the PIPAc project integrates AI, NMR, flow chemistry, and 3D-printed reactors for compact, mobile API manufacturing. Learn about real-time process monitoring, continuous flow optimization, modular reactor design, and case studies showcasing efficient, scalable, and safe pharmaceutical production, providing actionable insights for modern API synthesis.</p><h5><strong>Who should attend?</strong></h5><p>This webinar is designed for pharmaceutical scientists, bioprocess engineers, and quality assurance professionals, as well as anyone involved in pharmaceutical manufacturing and development. Attendees will gain practical insights to enhance process control, ensure product quality, and explore innovative NMR, PAT, and AI applications.</p><blockquote><p><strong>Presenter:</strong> Alejandro Bara-Estaún, PhD (Solution Product Manager for (bio)Process Analytical Technology, Bruker Biospin)</p><p>Alejandro Bara Estaun obtained his Ph.D. in Inorganic Chemistry at the University of Bath (UK) in collaboration with Bristol University and Evonik (Germany). He then undertook a two-year postdoctoral position at Bruker, leading the PIPAc project in collaboration with Alysohpil, Novalix, and De Dietrich. Recently, he transitioned into the role of Solution Product Manager for (bio)Process and Process Analytical Technology within Bruker’s Biopharma and Applied (BPA) division.</p><p><strong>Presenter:</strong> Philippe Robin (Co-founder and CEO of Alysophil)</p><p>Philippe Robin is the co-founder and CEO of Alysophil, a Strasbourg-based company developing solutions in continuous-flow chemistry enhanced by artificial intelligence for process control. Alysophil aims to improve the efficiency and sustainability of chemical production. Under his leadership, the company has launched projects such as Chempocket, modular micro-factories designed for flexible chemical synthesis, and PIPAc, a program dedicated to pharmaceutical processes, carried out with partners including De Dietrich, Bruker, and Novalix. Philippe Robin focuses on applying new technologies to support the chemical industry’s transition toward more flexible and responsible production models.</p><p><strong>Presenter:</strong> Luis Carrillo (Managing Director, De Dietrich France Dijon SAS)</p><p>Luis Carrillo is the Managing Director of De Dietrich Group’s subsidiary in Dijon, dedicated to developing engineering solutions through the integration of both in-house and third-party products. Dijon also serves as the hub for the Group’s innovation program, within which the PIPA’c project plays a pivotal role as a cornerstone for the future commercial development of these solutions. A chemist by training, Luis earned his degree from the University of Barcelona (Spain) and later completed a Master at IESE Business School. Luis Carrillo has been with the De Dietrich Group for more than 10 years, holding various positions across the organization. Luis Carrillo is committed to advancing sustainable innovation and strengthening the Group’s leadership in chemical engineering solutions. &nbsp;</p><p><strong>Presenter:</strong> Guillaume Bentzinger, PhD (Flow &amp; Process department, Novalix)</p><p>Guillaume Bentzinger joined Novalix as a Junior Project Manager in 2018 in the Synthetic Chemistry department. In 2019, he transitioned to the Process &amp; Flow department where he advanced to Project Manager and has been actively contributing to the development of flow chemistry at Novalix. He is leading the development of the chemistry under flow conditions for the PIPAc project. Guillaume Bentzinger studied organic chemistry in Strasbourg, at the IUT Robert Schuman Technical Institute, and later at the European School of Chemistry, Polymers and Materials (ECPM). In 2016, he completed his PhD in medicinal chemistry under the supervision of Professor Pascal Sonnet and Dr. Alexandra Dassonville-Klimpt at the University of Picardie Jules Verne in Amiens. In 2017, he pursued postdoctoral research in medicinal chemistry at Almac Discovery and the University of Belfast, under the supervision of Dr. Hugues Miel.</p></blockquote></div>

Bruker: Flow Chemistry Meets AI and NMR for Next-Gen API Production

Flow Chemistry Meets AI and NMR for Next-Gen API Production

Webinar on PIPAc: AI, NMR, flow chemistry & 3D-printed reactors for scalable, flexible API manufacturing with real-time monitoring and process optimization.

<div><p><strong>Pharmaceutical manufacturing faces growing demands for faster, more reliable testing while maintaining strict quality standards. Raman spectroscopy is transforming how laboratories meet these challenges with rapid, non-destructive analysis that requires little to no sample preparation.</strong></p><p>This webinar will showcase how this technology supports efficient, compliant and cost-effective testing across manufacturing workflows. Our expert speaker will also share insights into upcoming innovations that could further streamline processes and strengthen decision making.</p><p>Designed for professionals at all levels, this session will provide valuable knowledge to help you stay ahead in pharmaceutical testing.</p><h5><strong>Attend this webinar to:</strong></h5><ul><li>Understand the importance of testing in pharmaceutical manufacturing and the challenges encountered</li><li>Learn about comprehensive services such as data compliance, service and support to enhance testing processes</li><li>Understand the advanced capabilities of Raman spectroscopy in pharmaceutical manufacturing testing</li><li>Discover the benefits of Raman technology, including higher throughput, cost savings, time savings and higher uptime</li></ul><blockquote><p><strong>Presenter:</strong> Sudhir Dahal, PhD (Product Manager at Thermo Fisher Scientific)</p><p>Dr. Sudhir Dahal is the product manager of research Raman products at Thermo Fisher Scientific. The products include Raman microscopes and benchtop Raman spectrometers. He has worked with several spectroscopy techniques in the industry and has over 7 years of experience. He has a PhD from University of Maryland Baltimore County, where he researched and collaborated on developing a novel spectroscopy-based technique for brain tumor cell detection.</p></blockquote></div>

Technology Networks: Enhancing Pharmaceutical Manufacturing Using Raman Spectroscopy

Enhancing Pharmaceutical Manufacturing Using Raman Spectroscopy

Webinar on Raman spectroscopy in pharma. Explore rapid, non-destructive testing that boosts compliance, efficiency, and cost savings in manufacturing workflows.

Pharmaceutical Manufacturing by Raman Spectroscopy

<div><p><strong>From industrial coatings to ancient fossils, layer thickness analysis using micro-XRF is a powerful technique applied across diverse fields. Bruker micro-XRF for SEM (XTrace 2), combined with XMethod software, enables precise, non-destructive quantification of composition and thickness in complex multilayer structures.</strong></p><p>In this webinar, we will introduce the physical principles behind micro-XRF-based layer thickness analysis and demonstrate the layer thickness calculation procedures. You will also see practical workflows using XTrace 2 in object, line, and mapping modes.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Bruker_Elemental_distribution_of_a_printed_circuit_board_above_and_the_corresponding_elemental_distribution_of_its_layer_structure_build_on_Cu_Ni_and_Au_bottom_2d0d23a7ff.jpg" alt="Bruker: Elemental distribution of a printed circuit board (above) and the corresponding elemental distribution of its layer structure build on Cu, Ni and Au (bottom)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Bruker_Elemental_distribution_of_a_printed_circuit_board_above_and_the_corresponding_elemental_distribution_of_its_layer_structure_build_on_Cu_Ni_and_Au_bottom_2d0d23a7ff.jpg 210w," sizes="100vw" width="608" height="451"></p><h4><strong>We will discuss real-world examples from multiple application fields:</strong></h4><ul><li>Multilayer structures in printed circuit boards&nbsp;</li><li>Thin silver layers in photographic samples&nbsp;</li><li>Fossilized trilobite exoskeletons&nbsp;</li><li>Palladium coatings on nickel&nbsp;</li><li>Coatings on silicon wafers&nbsp;</li><li>Standard reference samples with known thicknesses</li></ul><p>We will also compare the traditional destructive SEM- and EDS-based methods with the non-destructive micro-XRF method in SEM, highlighting advantages in accuracy, efficiency, and sample preservation.</p><h4><strong>Who should attend?</strong></h4><ul><li>Scientists and researchers from all analytical fields interested in coating thickness calculation in SEM;</li><li>Micro-XRF users;</li><li>Experienced professionals managing electron microscopy labs.</li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Bruker_Non_destructive_thickness_evaluation_of_Trilobite_exoskeleton_gathered_with_XTRACE_2_Micro_XRF_in_SEM_Petrographically_well_kept_calcite_exoskeleton_has_10_m_in_thickness_446804baf4.jpg" alt="Bruker: Non-destructive thickness evaluation of Trilobite exoskeleton gathered with XTRACE 2 Micro-XRF in SEM. Petrographically, well-kept calcite exoskeleton has ~ 10 µm in thickness." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Bruker_Non_destructive_thickness_evaluation_of_Trilobite_exoskeleton_gathered_with_XTRACE_2_Micro_XRF_in_SEM_Petrographically_well_kept_calcite_exoskeleton_has_10_m_in_thickness_446804baf4.jpg 226w," sizes="100vw" width="608" height="420"></p><blockquote><p><strong>Presenter:</strong> Stephan Boehm (Product Manager - micro-XRF on SEM and WDS, Bruker Electron Microscope Analyzers)</p><p><strong>Presenter:</strong> Dr. Yang Yang (Application Scientist - micro-XRF on SEM and EDS, Bruker Electron Microscope Analyzers)</p></blockquote></div>

Bruker: Exploring Multi-Field Layer Thickness Capabilities with Micro-XRF in Scanning Electron Microscope

Exploring Multi-Field Layer Thickness Capabilities with Micro-XRF in Scanning Electron Microscope

We will introduce physical principles behind micro-XRF-based layer thickness analysis and demonstrate the layer thickness calculation procedures.

Multi-Field Layer Thickness Capabilities with Micro-XRF

<div><p><strong>Electron Backscatter Diffraction (EBSD) has long been a key technique for microstructural analysis in Scanning Electron Microscopy (SEM), widely adopted across both academic research and industrial applications. From mapping grain orientations in high performance alloys to probing deformation mechanisms in geological samples, EBSD continues to unlock critical insights into material properties.</strong></p><p>Our groundbreaking EBSD detector eWARP, which uses Direct Electron Detection (DED) technology, has been changing the EBSD landscape since its launch earlier this year. If you are not yet up to speed with eWARP now is the time to catch up!</p><p>This webinar will show you how eWARP, powered by a custom hybrid pixel sensor designed for EBSD applications, redefines EBSD performance by dramatically increasing signal efficiency and acquisition speed.</p><p>Curious about how eWARP can enhance your research? We will explore the use of eWARP in a range of applications, from materials science to nanotechnology, to show you what is now possible with the latest EBSD technology.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Bruker_Figure_1_Grain_Average_Misorientation_map_5e4fe4eeaa.jpg" alt="Bruker: Figure 1: Grain Average Misorientation map (false color) of bainitic steel, identifying regions with higher plastic deformation and dislocation density in green and yellow (&gt;6° misorientation)." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Bruker_Figure_1_Grain_Average_Misorientation_map_5e4fe4eeaa.jpg 235w," sizes="100vw" width="608" height="404"></p><h4><strong>What to Expect</strong></h4><ul><li><strong>Materials Science: </strong>See how eWARP enables ultra-fast phase and orientation mapping in complex metallic microstructures, revealing fine precipitates and phase transformation products at unprecedented clarity.</li><li><strong>Battery Research:</strong> Discover how high-resolution EBSD measurements quantitatively characterize boundary, grain and texture distributions in battery collector materials.</li><li><strong>Geoscience Applications:</strong> EBSD combined EDS phase identification helps you deciphering mineral deformation histories and crystallographic fabrics.</li><li><strong>Nanotechnology: </strong>Learn how direct detection pixelated sensor enhances TKD analysis of nanostructured thin films.</li><li><strong>Live Demo: </strong>Witness eWARP in action with a real-time EBSD acquisition showcasing its speed and precision.</li></ul><p>Whether you're advancing your research or exploring new analytical capabilities, this webinar provides a timely opportunity to learn how next-generation EBSD technology can support and elevate your research.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Bruker_Figure_2_Grain_Size_Distribution_map_random_coloring_of_NMC_cathode_material_used_in_Lithium_ion_battery_f16c7ee3be.jpg" alt="Bruker: Figure 2: Grain Size Distribution map (random coloring) of NMC cathode material used in Lithium-ion battery. In this measurement, 8500 grains were measured with eWARP in only 9 minutes (:measurement speed of 10 000 fps). The average grain size is less than 500 nm. The measurement was done at low accelerating voltage (10 kV) and probe current (13 nA) to reach the required fine step size of 20 nm" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Bruker_Figure_2_Grain_Size_Distribution_map_random_coloring_of_NMC_cathode_material_used_in_Lithium_ion_battery_f16c7ee3be.jpg 100w," sizes="100vw" width="608" height="955"></p><blockquote><p><strong>Presenter:</strong> Dr. Laurie Palasse (Global Application Manager, Bruker Electron Microscope Analyzers)</p><p><strong>Presenter:</strong> Dr. Meriem Ben Haj Slama (Application Scientist EBSD, Bruker Electron Microscope Analyzers)</p></blockquote></div>

Bruker: Catch Up with eWARP: Unmatched EBSD Performance

Catch Up with eWARP: Unmatched EBSD Performance

This webinar will show you how eWARP, powered by a custom hybrid pixel sensor designed for EBSD applications, redefines EBSD performance

<div><div id="inner_content_body_text" data-content-id="394785"><p><strong>The Litesizer DIF 500 was designed to make laser diffraction analysis as simple and intuitive as possible, without compromising precision.</strong></p><p>In this webinar, we’ll explore how every aspect of the instrument and its workflow was engineered for true user accessibility, including:</p><h5><strong>Quick-Click Measuring Modules</strong></h5><ul><li>Learn how the Quick-Click system allows you to switch seamlessly between liquid and dry dispersion in a single motion—no cables, tools, or complex setup required.</li></ul><h5><strong>Modular Design</strong></h5><ul><li>See how the modular design streamlines cleaning and maintenance, helping you move from one sample type to another in minutes.</li></ul><h5><strong>Intuitive Software</strong></h5><p>Kalliope™ software makes comparing datasets, reviewing trends, and reporting results effortless, thanks to its one-page workflow and smart QC tools.</p><h5><strong>Widest Particle Size Range</strong></h5><ul><li>With a range from 10 nm to 3.5 mm and best-in-class optical components, the Litesizer DIF is designed for precise, accessible measurements that enable accurate analysis of both small particles and complex mixtures.</li></ul><p>Whether in R&amp;D, quality control, or production, the Litesizer DIF 500 removes the typical barriers to efficient particle size analysis.</p><p>See for yourself how we have simplified every step, from setup to cleaning to data evaluation, to deliver an effortless and accurate particle size analysis experience from start to finish.</p><blockquote><p><strong>Presenter:</strong> Brian Rodenhausen</p><p>Dr. Brian Rodenhausen is the Principal Application Scientist in the Particle and Porous Materials Characterization group at Anton Paar USA. He has over a decade of experience teaching users the theory and practice of analytical instruments, as well as advising them on the design of experiments and interpretation of results. His research background focused on label-free characterization of asorbate layers at the solid-liquid interface. He received his Ph.D. in chemical engineering from the University of Nebraska-Lincoln (UNL) and did post-doctoral work at UNL and the Leibniz Institute of Polymer Research in Dresden, Germany.&nbsp;</p></blockquote></div></div>

Anton Paar: Effortless Particle Size Analysis – See the Difference

Effortless Particle Size Analysis – See the Difference

Learn how the Litesizer DIF 500 makes laser diffraction easy and precise with Quick-Click modules, modular design, smart software, and broad size range.

<p><strong>The Thermo Scientific Hypulse Surface Analysis System delivers a new approach to XPS depth profiling. It combines traditional ion beam milling with femtosecond laser ablation technology to help you accurately examine thin films, coatings, and multi-layer structures, all without the risk of chemical damage to the sample.</strong></p><p>Join us as we introduce the Hypulse System and highlight how it can help you revolutionize XPS depth profiling.</p><h5><strong>In this webinar, you will:</strong></h5><ul><li>Learn how femtosecond laser ablation delivers depth profiling to over 30 µm</li><li>Discover advanced depth profiling capabilities available with the Hypulse System</li><li>See how the combination of laser ablation and ion milling makes it possible to analyze a wider variety of materials</li></ul><blockquote><p><strong>Presenter:</strong> Tim Nunney</p><p>Tim is an applications development and marketing manager for the Thermo Scientific surface analysis (X-ray photoelectron spectroscopy) product line. He has been with Thermo Fisher Scientific since 2004, previously holding positions as an applications scientist, product manager, and in operations. Prior to joining Thermo Fisher, Tim worked as a post-doctoral research fellow at the University of Southampton investigating the dynamics of molecular dissociation on metal surfaces.</p></blockquote>

Thermo Fisher Scientific: Explore damage-free XPS depth profiling with the Hypulse Surface Analysis System

Explore damage-free XPS depth profiling with the Hypulse Surface Analysis System

Join us as we introduce the Hypulse System and highlight how it can help you revolutionize XPS depth profiling.

Damage-free XPS depth profiling with Hypulse Surface

<p><strong>Understand how TGA (thermogravimetric analysis) and DSC (differential scanning calorimetry) advance quality testing of biofuel end-products, including fatty acid decomposition at high temperatures, and freezing point determination in hydrocarbon mixtures for SAF applications. You'll learn about the benefits of Pyris™ DSC and HyperDSC®- providing high precision and super fast heating/cooling cycles. &nbsp;Plus we highlight the role of IR (infrared) and multi-position sample preparation units, which combined with thermal analysis, help you achieve comprehensive fuel and biofuel laboratory workflows.</strong></p><h4><strong>Highlights</strong></h4><ul><li>Biofuel market - testing techniques overview &amp; thermal analysis deep dive</li><li>Fatty acid decomposition at higher temperatures using TGA (research example from Alberta University)</li><li>Determining the freezing point of hydrocarbon mixtures for SAF applications using DSC (research example from Alberta University)</li><li>Role of IR featuring Spectrum Two™ and multi-position sample preparation units such as OilExpress</li></ul><blockquote><p><strong>Presenter: </strong>Bernardo Araujo Souto (PhD candidate) (Lecturer, University of Alberta)</p><p>Bernardo is part of the Biorefining Conversions and Fermentation Laboratory at the University of Alberta, where he works at the intersection of academia and industry to advance sustainable fuel technologies. He is a member of the group led by Dr. David C. Bressler, which focuses on developing and scaling bio-based solutions. Bernardo has been closely involved in collaborations with PerkinElmer, applying advanced analytical platforms to support innovation, scale-up, and industry-driven solutions in biomass conversion.<br><br><strong>Presenter:&nbsp;</strong>Dr. Krystelle Mafina PhD (Product Line Leader, PerkinElmer)</p><p>Dr. Krystelle Mafina is a product leader at PerkinElmer, overseeing the thermal (TEA) analysis business. She holds a PhD in Biomedical Biomaterials Science and is a Chartered Engineer (CEng) and Chartered Scientist (CSci) with a strong background in materials science.<br>A member of the Institute of Materials, Minerals, and Mining (IOM3) since 2009; a committee member since 2019, Krystelle is committed to continuous professional development and was recently made 'Fellow' of the institute. Her blend of scientific knowledge and industry experience makes her a valuable contributor to PerkinElmer and the wider scientific community.<br><br><strong>Presenter:&nbsp;</strong>Lucy Jenner (Sr. Marketing Manager &amp; Programs Lead)</p><p>Lucy Jenner is a CIM qualified marketing professional working at PerkinElmer since 2020. She develops strategy and manages marketing campaigns for industrial end-market sectors, across PerkinElmer's global customer base. Lucy is a graduate of Reading University and postgrad of Oxford College of Marketing.</p></blockquote>

PerkinElmer: Thermal & IR Studies Advancing Biofuel Production & Performance

Thermal & IR Studies Advancing Biofuel Production & Performance

Learn how TGA, DSC, and IR thermal analysis optimize biofuel testing, from fatty acid stability to SAF freezing point determination with PerkinElmer.