Join us for a free two-day LECO Separation Science Workshop on September 23–24, 2026, at the <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/companies/219">C³AL Laboratory</a> at Cal State LA. Registration is free, and meals and refreshments will be provided throughout the workshop.&nbsp;<h4>Registration</h4><blockquote>👉<a target="_blank" rel="noopener noreferrer" href="https://forms.cloud.microsoft/pages/responsepage.aspx?id=iYeNbqIuykW7qZP4_jUEVbznDB40eK1PgjPzhHyb__9URTFTTFA5UEEzQ1A4MUtFV0o4TEJTNlZCOS4u&amp;route=shorturl">Register HERE</a>Space is limited, register today!<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/LECO_LECO_Separation_Science_Workshop_registration_332543a18e.jpg" alt="LECO: LECO Separation Science Workshop - QR code for registration" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_LECO_LECO_Separation_Science_Workshop_registration_332543a18e.jpg 156w," sizes="100vw" width="437" height="437"></blockquote><h4>Hand-on Experience with the LECO Complex Chemical Composition Analysis Lab C3AL</h4><ul><li>Work directly with LECO instruments in the C3AL Laboratory</li><li>Learn complete analytical workflows from sample to answer</li><li>Get expert guidance from LECO application scientists</li><li>Develop methods and solve real-world challenges</li><li>Collaborate, ask questions, and build your skills</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Cal_State_LA_The_LECO_Pegasus_BTX_system_in_Cal_State_LA_s_LECO_Complex_Chemical_Compositional_Analysis_Lab_enhances_research_and_student_training_in_advanced_chemical_analysis_cover_b739e727ca.jpg" alt="Cal State LA: The LECO Pegasus BTX system in Cal State LA’s LECO Complex Chemical Compositional Analysis Lab enhances research and student training in advanced chemical analysis" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Cal_State_LA_The_LECO_Pegasus_BTX_system_in_Cal_State_LA_s_LECO_Complex_Chemical_Compositional_Analysis_Lab_enhances_research_and_student_training_in_advanced_chemical_analysis_cover_b739e727ca.jpg 227w," sizes="100vw" width="1252" height="863">The first day will focus on the fundamentals and theory of comprehensive two-dimensional gas chromatography (GC×GC), with an emphasis on understanding how GC×GC can enhance your research, solve complex analytical challenges, and support your laboratory or company goals.&nbsp;The second day will be dedicated to hands-on activities, giving participants the opportunity to work directly with LECO instrumentation, learn practical analytical workflows, and analyze their own samples with guidance from LECO application scientists.&nbsp;Whether you are new to GC×GC or looking to expand its use in your research or organization, this workshop offers a unique opportunity to learn, explore, and apply the technology in a practical setting. Space is limited, so register early!<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Cal_State_LA_LECO_QUADJET_G_Cx_GC_coupled_to_Pegasus_BT_4_D_TOM_MS_in_the_Complex_Chemical_Composition_Analysis_Lab_C_AL_077a14ae34/Cal-State-LA-LECO-QUADJET-GCxGC-coupled-to-Pegasus-BT-4D-TOM-MS-in-the-Complex-Chemical-Composition-Analysis-Lab-(CAL).jpg" alt="Cal State LA: LECO QUADJET GCxGC coupled to Pegasus BT 4D TOM MS in the Complex Chemical Composition Analysis Lab (C³AL)" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Cal_State_LA_LECO_QUADJET_G_Cx_GC_coupled_to_Pegasus_BT_4_D_TOM_MS_in_the_Complex_Chemical_Composition_Analysis_Lab_C_AL_077a14ae34/thumbnail_Cal-State-LA-LECO-QUADJET-GCxGC-coupled-to-Pegasus-BT-4D-TOM-MS-in-the-Complex-Chemical-Composition-Analysis-Lab-(CAL).jpg 234w," sizes="100vw" width="1949" height="1299">

LECO Separation Science Workshop

<h4>Latest edition of the Wiley Registry/NIST Mass Spectral Library for leading pharmaceutical, environmental, and forensic laboratories worldwide expands coverage to more than 1.2 million spectra</h4>Wiley, a global leader in authoritative content and research intelligence, today released the new edition of the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2591">Wiley Registry/NIST Mass Spectral Library</a>, a reference database that combines two essential mass spectrometry references in a single, integrated collection, giving scientists the full depth of both to identify unknown chemical compounds.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_Wiley_Registry_NIST_EI_Mass_Spectral_Library_2026_4d3c8f440f.jpg" alt="Wiley: Wiley Registry/NIST EI Mass Spectral Library 2026" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_Wiley_Registry_NIST_EI_Mass_Spectral_Library_2026_4d3c8f440f.jpg 110w," sizes="100vw" width="1524" height="2161">For years, laboratories doing GC-MS analysis have relied on Wiley’s renowned <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/887">Wiley Registry of Mass Spectral Data</a> and the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/products/2461">NIST/EPA/NIH EI Mass Spectral Library</a> from the U.S. government’s National Institute of Standards and Technology (NIST) to power their analytical workflows. These two respected references are united in this database, one of the most comprehensive resources of its kind.The new 2026 edition updates the collection, adding tens of thousands of newly validated compounds across both libraries and bringing the total to more than 1.2 million electron ionization (EI) mass spectra—unique chemical “signatures” used to identify substances.The Wiley Registry/NIST Mass Spectral Library is part of Wiley’s growing portfolio of scientific data and research intelligence solutions, which spans spectral databases, chemistry and materials literature, and analytical tools supporting researchers from discovery through applied outcomes.Wiley’s spectral database solutions are trusted by leading pharmaceutical, environmental, and forensic laboratories worldwide, reflecting Wiley’s mission to transform knowledge into actionable intelligence that helps researchers make confident, high-stakes decisions.<blockquote>“When a scientist runs a sample through a mass spectrometer, the results are only as good as the reference data behind them,” said Armughan Rafat, Wiley senior vice president and chief AI &amp; data analytics officer. “By uniting the Wiley Registry and the NIST Library in a single resource, we deliver the breadth, quality, and validation scientists need to identify unknown compounds faster and with confidence.”</blockquote>Available in the most common instrumentation manufacturer formats, the library supports high-confidence analysis across GC-MS workflows.<h4>Spectral Databases</h4>Spectral databases contain unique molecular “fingerprints” of substances captured through analytical techniques such as infrared (IR), mass spectrometry (MS), nuclear magnetic resonance (NMR), and Raman spectroscopy. By comparing experimental spectra against validated reference data, researchers can accurately identify unknown compounds across a wide range of applications. &nbsp;<h4>About Wiley</h4>Wiley is a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation, and learning. With more than 200 years at the center of the scholarly ecosystem, Wiley combines trusted publishing heritage with AI-powered platforms to transform how knowledge is discovered, accessed, and applied. From individual researchers and students to Fortune 500 R&amp;D teams, Wiley enables the transformation of scientific breakthroughs into real-world impact. From knowledge to impact—Wiley is redefining what’s possible in science and learning.&nbsp;

Wiley Releases Database Combining Two of the World’s Most Trusted Chemical Identification Resources

The countdown is almost over. In just one week, the international chromatography community will meet in Prague for the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/events/644">35th International Symposium on Chromatography (ISC 2026)</a>, taking place from September 6–10, 2026. Whether your registration has been confirmed for months or you are still deciding whether to join, now is the time to finalize your plans. Here is what you need to know before ISC 2026 begins.<a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/companies/314">ISC</a> is the oldest conference series dedicated to separation science, with symposia organized since 1956. This September, the Prague Congress Centre will welcome researchers, industry experts, instrument manufacturers, young scientists, and other specialists for five days of chromatography and separation science, covering everything from fundamental research to pharmaceutical, environmental, food, health, and omics applications.But before the scientific sessions begin, there are a few practical details worth checking.<h4>ISC officially starts on September 6 – but activities begin a day earlier</h4>The official dates for ISC 2026 are Sunday, September 6 through Thursday, September 10, but for some participants the conference starts already on Saturday, September 5.The first Short Courses are scheduled for Saturday (<a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/6770">SC 1 – Modern HPLC Separation in Theory and Practice</a> and <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7312">SC 2 – mzmine for LC-MS data analysis</a>), with additional courses continuing on Sunday morning and afternoon. If you have registered for a Short Course, make sure to check its exact date and starting time before arranging your journey to Prague.Sunday then marks the official opening of ISC 2026, with the Opening Ceremony, Award Ceremony, <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7361">plenary lectures</a>, and Welcome Reception introducing delegates to the week ahead.<h4>Haven’t registered yet? You can still join ISC 2026</h4>Missed the late-registration deadline? It is still possible to attend.Onsite registration has been available since August 26, 2026, giving last-minute participants another opportunity to join the symposium. Current onsite registration fees are:<ul><li>Industry: €1,150</li><li>Academic: €890</li><li>Student: €390</li><li>Short Courses: €270</li></ul>The Short Course fee covers participation in up to three Short Courses.One practical point for last-minute registration: bank-transfer payments closed on August 19, so only card payments are now accepted.Full registration includes access to oral and poster sessions, the exhibition, the Sunday Welcome Reception, scheduled lunches and coffee breaks, the electronic Book of Abstracts, and a Prague public transportation pass.<h4>Where is ISC 2026 and how do you get there?</h4>ISC 2026 will take place at the:Prague Congress Centre<ul><li>5. května 65</li><li>140 21 Prague 4</li><li>Czech Republic</li></ul>The venue is particularly easy to reach by public transport. It is located directly on Prague’s Metro Line C at Vyšehrad station, just around five minutes by metro from Muzeum station in the city centre.The Prague Congress Centre brings the lecture halls, exhibition spaces, meeting rooms, and other conference facilities together in one venue, making it easy to move between scientific sessions, posters, industry activities, and the exhibition throughout the day.And since full conference registration includes public transportation in Prague, getting around the city during ISC should be straightforward.<h4>When can you pick up your conference materials?</h4>The registration desk will already be open during the Short Courses and will remain available throughout the symposium.Registration opening hours:<ul><li>Saturday, September 5: 8:30–17:00</li><li>Sunday, September 6: 7:30–19:00</li><li>Monday, September 7: 7:30–18:00</li><li>Tuesday, September 8: 7:30–19:00</li><li>Wednesday, September 9: 8:00–18:00</li><li>Thursday, September 10: 8:30–14:30</li></ul>If you are arriving in Prague on Sunday, allowing some extra time for registration before the Opening Ceremony will make the start of the conference considerably more relaxed.<h4>Now is the time to build your personal ISC program</h4>With several parallel sessions running throughout the week, trying to decide where to go only after arriving at the venue may mean missing something important.The <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7477">main scientific program</a> is organized around three broad areas:<ul><li>Fundamentals</li><li>Bioanalysis and omics applications</li><li>Hyphenated techniques</li></ul>These are complemented by <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7280">Tutorials </a>+ Young Speakers, plenary and invited lectures, poster sessions, the international exhibition, vendor seminars, and industry-focused activities.Before leaving for Prague, take another look at the Interactive Program and mark the lectures, posters, and other activities that are most relevant to you. If you are presenting your own work, this is also the right time to double-check your assigned session, room, and presentation time.And don’t focus only on the oral program. Poster sessions and exhibition breaks are among the best opportunities to discuss new research directly with authors, meet instrument and technology specialists, and make new contacts.<h4>Don’t overlook the vendor seminars and industry program</h4>ISC 2026 is not limited to academic presentations. The conference also includes an extensive industry component, with activities covering current challenges in separation science and practical applications of new analytical technologies.During the lunchtime sessions, participants can attend <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7736">vendor seminars</a> presented by companies including Avantor, Shimadzu, Advanced Materials Technology, Restek, and Thermo Fisher Scientific. Topics range from stationary-phase selectivity and chromatographic modelling to HPLC and LC-MS column technologies and advanced characterization of biotherapeutics.The conference also includes dedicated <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7777">Industry Activities</a> from Monday through Wednesday, bringing together academic and industrial perspectives on topics relevant to analytical laboratories and the future of separation science. One of the discussions, for example, will examine how education in separation science can better reflect the skills required by modern industry, while another will focus on sustainability and the practical implementation of greener analytical workflows.On Wednesday, participants can also join the <a target="_blank" rel="noopener noreferrer" href="https://labrulez.com/en-us/all/article/7801">Publishing Workshop</a>, another activity worth adding to the schedule if scientific publishing is part of your work.<h4>Test your chromatography knowledge at the ISC Quiz</h4>Not every session needs to be completely serious.On Tuesday, September 8 from 18:30 to 19:30, ISC will host an interactive Chromatography Quiz, combining practical questions, chromatography fundamentals, unusual facts, and lighter challenges.There is no advance registration required. Any registered conference participant can join, but remember to bring a smartphone—the quiz uses live participation through a QR code.Results will be scored in real time, and prizes will be awarded to the top three participants.<h4>Start networking from the first evening</h4>The scientific program may be the main reason to attend ISC, but the conversations between sessions can be equally valuable.The first major networking opportunity comes immediately on Sunday.The Welcome Reception will take place on September 6 from 18:30 to 20:00 in the second-floor foyer of the Prague Congress Centre. It is open to registered participants and accompanying persons and includes a light buffet and drinks.As it takes place immediately after the opening program, it is an ideal opportunity to reconnect with colleagues, meet new contacts, and start conversations before the full parallel scientific program begins on Monday.Another social highlight will be the Gala Dinner on Wednesday, September 9 from 19:00 to midnight at the National House Vinohrady.The Gala Dinner requires a separate €100 ticket, is not included in the standard registration fee, and has a smart-casual dress code. Participants should also note that transportation to and from the venue is not organized by the conference.<h4>And perhaps leave a little time for Prague</h4>A conference schedule can fill up quickly, but ISC 2026 is taking place in one of Europe’s most walkable cities.If you find some free time between sessions, Vyšehrad is only about a 10-minute walk from the Prague Congress Centre and offers panoramic views across Prague and the Vltava River. It is an easy option for a short walk without travelling back into the historic city centre.See you at ISC 2026 in Prague!

ISC 2026 Starts in One Week: What You Need to Know

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The International Symposium on Chromatography (ISC) represents the oldest conference series focussing on separation science. ISC symposia have been organised since 1956 in each even year. ISC is internationally recognised as one of the premier meeting series for discussion of all modes of chromatography and separation science with a broad coverage of techniques and applications.

International Symposium on Chromatography - (ISC)

For over 200 years we have been helping people and organizations develop the skills and knowledge they need to succeed.
We develop digital education, learning, assessment, and certification solutions to help universities, businesses, and individuals move between education and employment and achieve their ambitions.

Wiley

In 1936, the Laboratory Equipment Company introduced the first rapid carbon determinator for the American iron and steel industry.  Today, almost 80 years later, LECO is recognized globally as a leader in the development of high-quality analytical instrumentation, mass spectrometers, comprehensive two-dimensional chromatography, metallography & optical equipment as well as consumables.

LECO

Thermo Scientific™ ISQ™ 7000 Single Quadrupole GC-MS System

Robust single quad GC-MS with advanced ion sources, NeverVent™ tech, SmartTune, and flexible software. Delivers sensitive, high-throughput routine analysis.

<h4>Unstoppable GC-MS performance for routine, regulatory, and high-throughput analysis</h4>The ISQ 7000 GC-MS system delivers reliable, scalable, and ultra-sensitive performance for routine analysis in food safety, environmental, clinical, and forensic laboratories. Designed to maximize uptime and analytical confidence, it features advanced ion source options, easy maintenance with NeverVent™ technology, and intuitive software tools like SmartTune and AutoSIM.<h3>Key Features and Benefits</h3><h4>🚀 Unstoppable Sensitivity</h4><ul><li>Advanced Electron Ionization (AEI) source for femtogram-level detection</li><li>Robust ExtractaBrite™ ion source, fully removable under vacuum</li><li>Dual-filament design and S-shaped ion optics reduce neutral and chemical noise</li><li>Simultaneous full-scan and SIM acquisition modes</li></ul><h4>⚙️ Unstoppable Uptime</h4><ul><li>NeverVent™ technology with Vacuum Probe Interlock (VPI) and V-Lock for maintenance without venting</li><li>Heated ion optics and RF lens protect quadrupole from matrix contamination</li><li>Reliable quadrupole design: solid, non-coated rods and maintenance-free performance</li><li>Up to 98% downtime reduction for routine interventions (e.g. source cleaning)</li></ul><h4>🧠 Smart Automation and Ease of Use</h4><ul><li>SmartTune for guided, fast, and consistent system tuning</li><li>AutoSIM and Timed-SIM (t-SIM) for efficient method creation</li><li>Retention Time Alignment (RTA) tool for consistent results across column changes</li><li>Deconvolution tools for untargeted compound identification</li></ul><h4>🧪 Flexible Analytical Capabilities</h4><ul><li>EI, PCI, NCI ionization modes (with optional dual reagent gas switching)</li><li>Mass range: 1.2–1100 u; scanning speed up to 240 scans/s</li><li>Optional Direct Insertion and Direct Exposure probes for solid samples</li><li>Software-switchable ionization modes in a single analysis</li></ul><h4>🖥️ Integrated Software and Data Handling</h4><ul><li>Full control via <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/76">Chromeleon™ CDS</a> or <a target="_blank" rel="noopener noreferrer" href="https://gcms.labrulez.com/products/77">TraceFinder™</a></li><li>Preloaded application libraries and eWorkflows (e.g. US EPA, clinical, toxicology)</li><li>Auto-calibration, QA/QC tools, and compliance-ready (21 CFR Part 11)</li><li>Seamless LIMS connectivity and user-guided reporting tools</li></ul><h4>🔁 Sample Introduction Options</h4><ul><li>Compatible with AI/AS 1310, TriPlus 300 (HS), and TriPlus RSH autosamplers</li><li>Robotic workflows including dilution, standard addition, and derivatization</li><li>Ideal for trace analysis in complex matrices and high-throughput environments</li></ul><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/application::product.product/isq-7000-trace-1310-triplus-rsh-left-1200x1200.jpg-650_s.webp" alt="Thermo Scientific™ ISQ™ 7000 Single Quadrupole GC-MS System" width="382" height="382">

Thermo Scientific ISQ™ 7610 Single Quadrupole GC-MS

Thermo Scientific ISQ™ 7610 Single Quadrupole GC-MS. Simplified operation, automated workflows, and extended dynamic range deliver consistent results from system to system in every laboratory.

To stay ahead, analytical testing laboratories need the ultimate confidence of a GC-MS system that easily and reliably produces trusted results, day after day. For this, you can count on the Thermo Scientific™ ISQ™ 7610 Single Quadrupole GC-MS System. Simplified operation, automated workflows, and extended dynamic range deliver consistent results from system to system in every laboratory. Thermo Scientific™ NeverVent™ technology, extended-life detector, and intelligent software eliminate unnecessary downtime to maximize sample throughput. To ensure you are ready for any analytical challenge, the system is upgradeable from entry-level to advanced configurations. Now you can take the lead with rapid return on investment (ROI) for your regulated GC-MS analyses.<h4>Unstoppable confidence in quantitative performance</h4>Delivers femtogram-level sensitivity so you consistently meet required detection limits as you run samples, whether you run in SIM mode or Full Scan. The ISQ 7610 GC-MS features a unique ion path that neutral particles cannot navigate and a choice of an ExtractaBrite or AEI ion source, depending on your sensitivity needs. The instrument’s XLXR detector which is an electron multiplier detector has an extended lifetime and extended dynamic range. Extended dynamic range capability enables labs to combine methods allowing analysis of low- and high-concentration compounds in a single run.<h4>The right choice for any workflow</h4>The intuitive <a target="_blank" rel="noopener noreferrer" href="https://www.thermofisher.com/cz/en/home/industrial/chromatography/chromatography-data-systems-cds.html">Thermo Scientific Chromeleon Chromatography Data System (CDS)</a> is available to help streamline quantitative workflows and ready-to-use Thermo Scientific eWorkflows can be downloaded from the <a target="_blank" rel="noopener noreferrer" href="https://appslab.thermofisher.com/">Thermo Scientific Appslab Library of Analytical Applications</a> to jump-start your method development. For U.S. EPA-based environmental applications, the Environmental Analysis Extension pack provides a set of GC-MS e-workflow and reporting templates.<h4>Unstoppable instrument uptime for full-time productivity</h4>The robust design of the ISQ 7610 GC-MS ensures that the system can work continuously to produce the highest quality results possible. High matrix tolerance minimizes routine maintenance, but when maintenance is required, the NeverVent technology available with the ExtractaBrite ion source enables source cleaning, column replacement or injector maintenance without requiring downtime to vent the instrument, so more time can be spent producing results.<h4>Ease of use that helps you stay ahead</h4>Automated software for instrument tuning, method development, targeted quantification and untargeted screening workflows make the ISQ 7610 GC-MS system easy to learn and enables quick transition to this system from other platforms. The ISQ 7610 Single Quadrupole GC-MS System features user-centric innovations including instrument health monitoring assists you in determining when maintenance is needed to avoid unnecessary downtime. As a result, you maximize instrument utilization, sample throughput, and ultimately ROI.<h4>Unstoppable confidence in your future</h4>To ensure you are ready for any analytical challenge, the ISQ 7610 Single Quadrupole GC-MS System is fully upgradable from entry-level to advanced configurations. Now you can be confident that your laboratory can adapt to new challenges using the same investments in GC-MS technology.<h3>Specifications</h3><ul><li>Mass Range: 1.2–1100 u with unit mass resolution&nbsp;</li><li>Type:&nbsp;Single Quadrupole GC-MS</li><li>Detectors:&nbsp;Triple off-axis Thermo Scientific™ DynaMax™ XTEND XR detection system, with off-axis 10 kV dynode, discrete dynode electron multiplier and electrometer, linear from 0 to 110 μA</li><li>Modes:&nbsp;Electron Impact Ionization (EI), with Full Scan (FS), SIM, and FS/SIM, Simultaneous within the same injection</li><li>Scanning Capabilities:&nbsp;Fast Quadrupole Scanning up to 20,000 U/s</li><li>Source Type:&nbsp;Advanced Electron Ionization (AEI) Source for Ultra-Sensitivity and Robustness</li><li>Item Description:&nbsp;Scalable GC-MS platform, fully upgradable from a base configuration to an advanced highly sensitive configuration</li><li>Description:&nbsp;ISQ 7610 Large Turbo, No VPI with AEI</li><li>Mass Stability:&nbsp;Better than 0.1 u/48 hours/∆T ≤2 K</li><li>Dimensions:&nbsp;46 x 36 x 69 cm (18 x 14 x 27 in) (H x W x D)</li><li>Mass Analyzer:&nbsp;Dual-stage mass filter with off-axis ion guide pre-filter for noise reduction and solid, homogeneous non- coated, maintenance-free quadrupole rods</li></ul>

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