Analysis of characteristic flavor compounds in coffee peels subjected to different thermal processing treatments based on GC–IMS and HS-SPME–GC–MS combined with chemical pattern recognition

Forced degradation analysis of recombinant adeno-associated virus serotype 8 based on analytical anion exchange chromatography coupled to orthogonal characterization

Combining elemental analysis and molecular techniques to characterize Ancient Egyptian mummification balms

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Thermo Scientific™ Dionex™ Inuvion™ Core ion chromatography system

The Inuvion Core system gives you all the benefits of chemical suppression and higher-pressure operation, with manual eluent preparation.

<h3><strong>Welcome to the evolution of everyday IC reliability</strong></h3><p>The new<strong> Thermo Scientific™ Dionex™ Inuvion™ ion chromatography system</strong> makes ion analysis simpler and more intuitive than ever before. And it delivers exactly what a busy analytical testing lab is looking for: <strong>consistently excellent results-every shift, every day, for every operator.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Dionex_Inuvion_ion_chromatography_system_2_6400708696.jpg" alt="Thermo Scientific™ Dionex™ Inuvion™ ion chromatography system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Dionex_Inuvion_ion_chromatography_system_2_6400708696.jpg 245w," sizes="100vw" width="825" height="498"></p><h3><strong>Start with Inuvion Core</strong></h3><p>The <strong>Inuvion Core system</strong> gives you<strong> </strong>all the benefits of chemical suppression and higher-pressure operation, with manual eluent preparation. You still enjoy the<strong> same robust Dionex Inuvion platform</strong>-easily configurable and economically upgradeable to full-featured capabilities as budget allows.</p><figure class="image"><img style="aspect-ratio:650/650;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Dionex_Inuvion_Core_ion_chromatography_system_6c8824cb1d.jpg" alt="Thermo Scientific™ Dionex™ Inuvion™ Core ion chromatography system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Dionex_Inuvion_Core_ion_chromatography_system_6c8824cb1d.jpg 156w," sizes="100vw" width="650" height="650"></figure><h3><strong>SIMPLE, INTUITIVE USER EXPERIENCE&nbsp;</strong></h3><ul><li><strong>Smart, function-driven design</strong> lets you quickly and safely access everything on the instrument—no hard-to-reach compartments, and no step stools or extra tools needed!</li><li><strong>Automated startup and shutdown routines</strong> ensure the system is quickly ready for the day’s work without user intervention.&nbsp;</li><li><strong>Built-in how-to videos</strong> reduce training time and simplify setup and operation.</li></ul><h3><strong>ULTRA-RELIABLE PERFORMANCE&nbsp;</strong></h3><ul><li><strong>Advanced high-performance pump technology and electronics</strong> let you take advantage of a wider range of columns and chemistries to improve the speed and quality of your results.</li><li><strong>Fast, flexible, convenient electrolytic suppression: </strong>Just connect the suppressor; no external pump or offline conditioning needed for regeneration.</li><li><strong>Reagent-free IC (RFIC™) capability</strong> makes eluent preparation as simple as “just add water,” while ensuring more consistent results and enabling optimized gradient separations.</li></ul><h3><strong>EASILY CONFIGURABLE AND UPGRADEABLE</strong></h3><ul><li><strong>Versatile, adaptable platform</strong> lets you configure the exact Dionex Inuvion IC system for today’s needs and budget, with confidence that your system will also meet your future needs.</li><li><strong>Multiple options and peripherals </strong>extend IC capabilities, letting you easily—and cost-effectively—adapt to changing sample types and workflow requirements.</li></ul><h3><strong>Simply the best system for everyday ion analysis</strong></h3><figure class="image"><img style="aspect-ratio:1107/755;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Dionex_Inuvion_ion_chromatography_system_d855feb2a8.jpg" alt="Thermo Scientific™ Dionex™ Inuvion™ ion chromatography system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Dionex_Inuvion_ion_chromatography_system_d855feb2a8.jpg 229w," sizes="100vw" width="1107" height="755"></figure><p><strong>1. Operator-friendly engineering </strong>saves time and reduces errors by allowing easy, unobstructed access to all components, connections and consumables</p><p><strong>2. Compact design </strong>helps you make the most of valuable bench space</p><p><strong>3. Digital gas pressure regulator </strong>increases precision of gas delivery for maximum day-to-day consistency (optional)</p><p><strong>4. Temperature-controlled conductivity cell </strong>improves reproducibility and ensures baseline stability</p><p><strong>5. Vacuum degassing capability</strong> enables more consistent peak identification from smoother baselines</p><p><strong>6. Seal wash pump</strong> reduces maintenance costs when using manually prepared eluents (optional)&nbsp;</p><p><strong>7. Reagent-free IC (RFIC)</strong> saves time and ensures greater day-to-day and operator-to-operator consistency, while also allowing the use of gradient separations</p><p><strong>8. Electrolytic suppression</strong> entirely eliminates the need for manual regenerant preparation (or, opt for a continuously regenerated, always- ready-to-go chemical suppressor)</p><p><strong>9. Thermo Scientific™ Dionex™ IC PEEK Viper™ fittings</strong> ensure confident, low dead volume connections every time—no tools required! (optional)</p><p><strong>10. Integrated column heater</strong> minimizes the impact of fluctuations in lab temperature that can adversely affect results (optional)</p><p><strong>11. 6- or 10-port auxiliary valve</strong> lets you automate in-line sample preparation</p><p><strong>12. State-of-the-art high-pressure pump (up to 5000 psi)</strong> lets you increase flow rates with smaller particle columns to reduce run times or add additional separation capacity with longer column length</p><p><strong>13. System self-diagnostics </strong>automatically detect any issues with hardware and consumables</p><p><strong>14. Self-service capabilities and user-swappable parts</strong> help you get back up and running in a hurry Automatic eluent monitor alerts the operator to low solution levels, avoiding potential system damage or failed runs (optional)</p><p><strong>15. Automatic eluent monitor </strong>alerts the operator to low solution levels, avoiding potential system damage or failed runs (optional)</p><h3><strong>Flexible, adaptable Dionex Inuvion platform</strong></h3><p>You can <strong>configure your Dionex Inuvion system</strong> to meet specific analytical and budget requirements, and easily reconfigure as needed. Multiple configurations and peripherals extend IC capabilities, letting you easily-and cost-effectively-adapt to changing sample types and workflow requirements.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Dionex_Inuvion_ion_chromatography_system_3_fa8233bcd4.jpg" alt="Thermo Scientific™ Dionex™ Inuvion™ ion chromatography system." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Dionex_Inuvion_ion_chromatography_system_3_fa8233bcd4.jpg 245w," sizes="100vw" width="1246" height="572"></p><h3><strong>Consistently excellent results every day</strong></h3><p>The <strong>Dionex Inuvion IC system supports a full range of columns </strong>to improve the speed and quality of results, for both<strong> anions and cations.</strong> Expanded capabilities, such as Reagent-Free IC (RFIC), enhance operator-to-operator consistency, while enabling the use of eluent gradients to optimize separations.</p><h4><strong>Rapid results</strong></h4><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Obr_2_Ukazka_rychle_separace_zakladnich_aniontu_s_uhlicitanovou_MF_Zkraceni_doby_analyzy_diky_typu_kolony_a_vyssimu_prutoku_0e610b919d.jpg" alt="Thermo Scientific™ Dionex™ Inuvion™ Core ion chromatography system: Figure 1. Elution of seven common inorganic anions using carbonate eluent. Short columns and fast flow rates let you reduce run times." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Pragolab_Obr_2_Ukazka_rychle_separace_zakladnich_aniontu_s_uhlicitanovou_MF_Zkraceni_doby_analyzy_diky_typu_kolony_a_vyssimu_prutoku_0e610b919d.jpg 245w," sizes="100vw" width="1622" height="739"></p><h4><strong>Exceptional reproducibility</strong></h4><figure class="image"><img style="aspect-ratio:1693/754;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Obr_3_Ukazka_reprodukovatelnosti_analyzy_zakladnich_aniontu_40_nastriku_Spickova_technologie_cerpadla_a_elektronika_pristroje_poskytuji_konzistentni_a_reprodukovatelne_vysledky_f66e7430cf.jpg" alt="Thermo Scientific™ Dionex™ Inuvion™ Core ion chromatography system: Figure 2. Overlay of 40 replicate injections. State-of-the-art pump technology and Electronics deliver consistent, reproducible results." width="1693" height="754"></figure><h4><strong>Increased sensitivity and consistency</strong></h4><figure class="image"><img style="aspect-ratio:1860/836;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Obr_4_Ukazka_vysoce_citlive_analyzy_aniontu_ve_vodach_Eluent_generator_KOH_a_elektrolyticka_suprese_snizuji_pozadi_cimz_dochazi_ke_zvyseni_citlivosti_da55facfd0.jpg" alt="Thermo Scientific™ Dionex™ Inuvion™ Core ion chromatography system: Figure 3. Determination of inorganic anions in drinking and surface waters. KOH eluent generation and electrolytic suppression yield lower backgrounds for greater sensitivity and increased day-to-day consistency." width="1860" height="836"></figure><h4><strong>Method optimization</strong></h4><figure class="image"><img style="aspect-ratio:1799/889;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_Obr_5_Ukazka_optimalizace_metody_zkraceni_doby_analyzy_pouzitim_gradientu_mobilni_faze_fc1fbe9cb0.jpg" alt="Thermo Scientific™ Dionex™ Inuvion™ Core ion chromatography system: Figure 4. Comparison of isocratic and gradient runs using eluent generation. Reduce run length and sharpen later-eluting peaks with the same ease as an isocratic run with no need for two separate eluents or a proportioning pump." width="1799" height="889"></figure><h3><strong>Compliance-ready Chromeleon CDS</strong></h3><p>A trusted industry standard all over the world, ”Simply Intelligent”<strong> </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/76"><strong>Thermo Scientific™ Chromeleon™ Chromatography Data System (CDS) software </strong></a>brings out the full power of the Dionex Inuvion IC system. Easy to learn and easy to use, it automates and optimizes daily tasks and helps even inexperienced users achieve consistent, high quality results.</p><p><img style="aspect-ratio:3700/1660;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Thermo_Scientific_Dionex_Inuvion_2_303a6eb73b.jpg" alt="Thermo Scientific™ Dionex™ Inuvion™ Core ion chromatography system." width="3700" height="1660"></p>

Thermo Scientific TraceGOLD™ TG-1MS GC Columns

Choose the nonpolar Thermo Scientific™ TraceGOLD™ TG-1MS GC column for optimal signal-to-noise ratio, sensitivity, and MS integrity. 

<p><strong>Achieve consistent results with this low-bleed, stable column. For optimal signal-to-noise ratio, sensitivity and MS integrity for a wide variety of applications, the nonpolar TraceGOLD TG-1MS GC column is an excellent choice.</strong></p><figure class="image"><img style="aspect-ratio:1377/843;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Thermo_Trace_GOLD_TG_1_MS_721a943897/Pragolab-GC-kolona-Thermo-TraceGOLD-TG-1MS.jpg" alt="Thermo Scientific™: TraceGOLD™ TG-1MS GC Columns" width="1377" height="843"></figure><h4><strong>Engineered for Superior Performance:</strong></h4><ul><li>Nonpolar, 100% dimethyl polysiloxane</li><li>Equivalent to USP G2</li><li>Exceptionally low-bleed</li></ul><h4><strong>A Leap Forward in Performance with Low-Bleed and Superior Inertness:</strong></h4><ul><li>Low baseline noise enables improved limits of detection with enhanced resolution of low-level analytes.</li><li>Minimizing column bleed extends the column lifetime, leading to higher productivity.</li><li>Reducing column bleed increases reproducibility of the stationary phase over time, resulting in greater run-to-run and batch-to-batch reproducibility.</li><li>Superior inertness ensures excellent peak shape and sensitivity, especially for highly active or difficult to analyze compounds.</li></ul><h4><strong>Recommended For:</strong></h4><ul><li>Hydrocarbons</li><li>GROs</li><li>Drugs of Abuse</li><li>PCBs</li></ul><h4><strong>Alternative Uses:</strong></h4><ul><li>Chlorinated aromatics</li><li>Organochlorine pesticides</li><li>Organophosphorous pesticides</li><li>Polycyclic aromatic hydrocarbons (PAHs)</li><li>Paraffins</li><li>Polywax</li><li>Pyrethroids</li><li>Semivolatiles</li><li>Xylenes</li></ul><h4><strong>Similar To:</strong></h4><ul><li>Rxi™-1ms</li><li>DB-1</li><li>DB-1ms</li><li>HP-1</li><li>HP-1ms</li><li>Ultra-1</li><li>SPB™-1</li><li>Equity™-1</li><li>VF-1ms</li><li>CP-Sil 5 CB Low Bleed/MS</li></ul>

Thermo Scientific TraceGOLD™ TG-1 MT Metal GC Columns

Push the limits of your analyses with Thermo Scientific™ TraceGOLD™ TG-1MT GC Columns. These nonpolar, metal columns allow you to work a temperatures up to 430°C

<p><strong>Push the limits of your analyses with Thermo Scientific™ TraceGOLD™ TG-1MT GC Columns. These nonpolar, metal columns allow you to work a temperatures up to 430°C with no compromise in performance when analyzing highly active and aggressive compounds.</strong></p><h4><strong>Engineered for Superior Performance:</strong></h4><ul><li>Nonpolar, 100% dimethyl polysiloxane</li><li>Low bleed for excellent signal-to-noise ratio, sensitivity and mass spectral integrity</li><li>Stable to 430°C</li><li>USP Type: G1, G2, G38</li></ul><h4><strong>A Leap Forward in Performance with Low-Bleed and Superior Inertness:</strong></h4><ul><li>A low bleed, stable column produces consistent results.</li><li>Low baseline noise enables improved limits of detection with enhanced resolution of low level analytes. Minimizing column bleed extends the column lifetime, leading to higher productivity.</li><li>Reducing column bleed increases reproducibility of the stationary phase over time, resulting in greater run-to-run and batch-to-batch reproducibility.</li><li>Superior inertness ensures excellent peak shape and sensitivity, especially for highly active or difficult compounds.</li></ul><h4><strong>Applications:</strong></h4><ul><li>Hydrocarbons</li><li>Solvent impurities</li><li>Polychlorinated biphenyl (PCB) congeners</li><li>Aroclor mixes</li><li>Simulated distillation</li><li>Drugs of abuse</li><li>Natural gas odorants</li><li>Essential oils</li><li>Pesticides</li></ul><h4><strong>Alternative Uses:</strong></h4><ul><li>Chlorinated aromatics</li><li>Organochlorine pesticides</li><li>Organophosphorous pesticides</li><li>Polycyclic aromatic hydrocarbons (PAHs)</li><li>Paraffins</li><li>Polywax</li><li>Pyrethroids</li><li>Semivolatiles</li><li>Xylenes</li></ul><h4><strong>Similar To:</strong></h4><ul><li>MXT™-1</li><li>DB-1</li><li>DB-1MS</li><li>HP-1</li><li>HP-1MS</li><li>Ultra-1</li><li>SPB™-1</li><li>Equity™-1</li><li>MDN-1</li><li>CP-Sil 5 CB</li><li>VF-1ms</li><li>ZB-1HT</li></ul>

Thermo Scientific™ LipidSearch™ Software

Thermo Scientific™ LipidSearch™ software provides accurate identification of lipids and automatically integrates complex data into a concise report.

<h3><strong>The promise of lipidomics</strong></h3><p><strong>Lipidomics is a new field of study crucial for understanding cellular physiology and pathology. The application of lipidomic profiling to disease phenotype analysis is a rapidly growing aspect of translational medical research. Identification of unique lipid biomarkers has the potential to distinguish healthy individuals from individuals at risk for disease, detect diseases earlier, and facilitate development of personalized treatments.</strong></p><p>Liquid chromatography combined with mass spectrometry (LC/MS) is a widely adopted technique for lipidomics analyses. Relative and absolute quantitation, and identification, of lipids from biological samples requires sophisticated software with an extensive, comprehensive database.<strong> Thermo Scientific™ LipidSearch™ software provides accurate identification of lipids and automatically integrates complex data into a concise report. With its easy-to-use web-based interface, it dramatically reduces data analysis time.</strong></p><figure class="image"><img style="aspect-ratio:915/494;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Lipid_Search_Software_2_73b7d0a9e2.jpg" alt="Thermo Scientific™ LipidSearch™ Software: Easy-to-use web browser interface for automated and reliable identification." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Lipid_Search_Software_2_73b7d0a9e2.jpg 245w," sizes="100vw" width="915" height="494"></figure><h3><strong>Automated identification and relative quantitation with LipidSearch software</strong></h3><p>LipidSearch software, developed jointly by Professor Ryo Taguchi and MKI, (Tokyo, Japan), is a powerful new tool for<strong> automatic identification and relative quantification of cellular lipid molecular species from large amounts of mass spectrometric data obtained in nano-infusion or LC-MS experiments. </strong>Using the industry-leading, high-resolution, accurate-mass <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=5&amp;manufacturerItems=3&amp;search=orbitrap"><strong>Thermo Scientific Orbitrap™ technology</strong></a> with exclusive<strong> LipidSearch software</strong>, the most accurate and confident lipid profiles and identifications can be achieved more quickly than ever before.</p><ul><li><strong>Compatible with</strong> data acquired from Thermo Scientific™ triple quadrupole, ion trap, and Orbitrap mass spectrometers</li><li><strong>Largest lipid database</strong> containing <strong>&gt;1.5 million</strong> lipid ions and their predicted fragment ions</li><li><strong>Identification algorithms</strong> for product ion, precursor ion and neutral loss scans</li><li><strong>Alignment of lipid data</strong> obtained from multiple<strong> LC-MS and MS<sup>n</sup> experiments</strong></li><li><strong>Relative quantitation </strong>of identified lipid precursors in either LC-MS or infusion experiments</li></ul><p>The database contains <strong>defined structures and includes more than 1.5 million lipid ions and their predicted fragment ions. </strong>Fragmentation patterns are calculated and improved by using expert knowledge based on experimental results. Lipid adduct ions and MS<sup>n</sup> fingerprints are also included. Data are stored in XML files and are easily customized.</p><figure class="image"><img style="aspect-ratio:990/497;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Lipid_Search_Software_3_91f1458663.jpg" alt="Thermo Scientific™ LipidSearch™ Software: Lipid fragment ions related to lipid headgroup, fatty acids, and backbone." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Lipid_Search_Software_3_91f1458663.jpg 245w," sizes="100vw" width="990" height="497"></figure><h3><strong>LipidSearch software provides an easy-to-use, automated workflow</strong></h3><p><strong>From peak detection to relative quantitaiton and identification, LipidSearch software provides an easy-to-use, automated workflow.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Lipid_Search_Software_4_2043f3d667.jpg" alt="Thermo Scientific™ LipidSearch™ Software: LipidSearch software provides an easy-to-use, automated workflow." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Lipid_Search_Software_4_2043f3d667.jpg 245w," sizes="100vw" width="1122" height="530"></p><h4><strong>Step 1 Data Analysis Module — Peak Detection</strong></h4><ul><li><strong>Raw data file reading</strong></li><li><strong>Smart peak detection</strong></li></ul><p>The peak detection engine implemented in<strong> LipidSearch software </strong>can handle<strong> different MS experiments and platforms. </strong>The combination of unique peak detection algorithms, tailored for each experiment and instrument type, and mass spectral processing functions enables accurate peak detection.</p><p><strong>LipidSearch software provides two different identification algorithms as well as scoring algorithms:</strong></p><ul><li><strong>A group-specific algorithm</strong> identifies lipids based on the polar head groups or fatty acids using a combination of precursor ion scanning and neutral loss scans from lipids mixtures.</li><li><strong>The comprehensive ID algorithm</strong> is used for product ion scans and can discriminate each lipid by matching the predicted fragmentation pattern stored in the database.</li><li>LipidSearch software also provides a <strong>set of scoring algorithms</strong> to filter out lower probability results</li></ul><h4><strong>Step 2 Identification Module — Lipid Identification</strong></h4><ul><li><strong>Group-specific ID (targeted)</strong></li><li><strong>Comprehensive ID (untargeted)</strong></li><li><strong>Scoring algorithms</strong></li></ul><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Lipid_Search_Software_5_0abd534dd5.jpg" alt="Thermo Scientific™ LipidSearch™ Software: PG 17:0/17:0 Search Results." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Lipid_Search_Software_5_0abd534dd5.jpg 245w," sizes="100vw" width="1003" height="456"></p><h4><strong>Step 3 Quantitation Module — Alignment and Quantitation</strong></h4><ul><li><strong>XIC peak integration</strong></li><li><strong>Retention time alignment</strong></li><li><strong>Relative quantitation</strong></li><li><strong>Statistical analysis</strong></li></ul><p>Prior to quantitation, lipid results from each sample are aligned within a retention time window. Identified lipids are quantified by detecting their precursor ions from full-scan MS and integrating extracted ion chromatograms.</p><p>Accurate peak areas are computed by denoising and smoothing the peak profiles prior to separating any partially overlapped peaks. Comparative analysis is then carried out between the multiple sample and control groups using <strong>t-test statistics.</strong> The mean peak area result for each group is displayed in a “box and whisker” plot.</p><figure class="image"><img style="aspect-ratio:1129/909;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Lipid_Search_Software_6_196073034c.jpg" alt="Thermo Scientific™ LipidSearch™ Software: Alignment results for CoQ7, [M+NH4]+." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Lipid_Search_Software_6_196073034c.jpg 194w," sizes="100vw" width="1129" height="909"></figure><p>Using the industry-leading, high-resolution, accurate-mass <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=5&amp;manufacturerItems=3&amp;search=orbitrap"><strong>Thermo Scientific™ Orbitrap™ technology</strong></a><strong> </strong>with exclusive<strong> LipidSearch software</strong>, achieve the most accurate and confident lipid profiles and identifications more quickly than ever before. For targeted quantitation, LipidSearch software also supports the <a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products?category=5&amp;manufacturerItems=3&amp;search=tsq"><strong>Thermo Scientific TSQ triple quadrupole MS systems</strong></a><strong>. </strong>For both lipidomics workflows, LipidSearch software <strong>automatically integrates complex data into a combined report to dramatically reduce data analysis.</strong></p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Lipid_Search_Software_7_f6a5102f0a.jpg" alt="Thermo Scientific™ LipidSearch™ Software." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Lipid_Search_Software_7_f6a5102f0a.jpg 245w," sizes="100vw" width="924" height="570"></p><h5><strong>Minimum/Recommended PC Requirements</strong></h5><ul><li><strong>OS: </strong>Microsoft® Windows® 7 Professional (x64) or Windows 8 (x64); English language<br><strong>CPU: </strong>Quad - or multi-core CPU, 2 GHz or higher<br><strong>Memory:</strong> 8 GB RAM or higher<br><strong>HDD: </strong>50 GB free space for LipidSearch software; 500 GB hard drive<br>SSD (optional): 50 GB free space for LipidSearch software; 256 GB solid-state drive</li></ul>

Thermo Scientific TraceGOLD™ TG-5MS GC Columns

Employ the most widely used MS phase in gas chromatography with the 5% phenyl phase Thermo Scientific™ TraceGOLD™ TG-5MS GC Column.

<p><strong>Employ the most widely used MS phase in gas chromatography with the 5% phenyl phase TraceGOLD TG-5MS GC Column.</strong></p><ul><li>Low polarity phase, 5% diphenyl/95% dimethyl polysiloxane</li><li>Low bleed for excellent signal-to-noise ratio, sensitivity and mass spectral integrity</li><li>Exceptional inertness ideal for analysis of active compounds</li><li>Equivalent to USP G27 phase</li></ul><figure class="image"><img style="aspect-ratio:1411/863;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Trace_GOLD_TG_5_MS_GC_columns_a9e173e392/Pragolab-GC-kolona-TraceGOLD-TG-5MS-GC-columns.jpg" alt="Thermo Scientific: TraceGOLD™ TG-5MS GC Columns" width="1411" height="863"></figure><h4><strong>Recommended for:</strong></h4><ul><li>Semivolatiles</li><li>Phenols</li><li>Amines</li><li>Residual solvents and solvent impurities</li><li>Drugs of abuse</li><li>Pesticides</li><li>PCB cogeners</li><li>Aroclor mixes</li></ul><h4><strong>Similar to:</strong></h4><ul><li>Rxi™-5ms</li><li>DB-5</li><li>HP-5</li><li>HP-5ms</li><li>Ultra-2</li><li>SPB-5</li><li>Equity-5</li><li>CP-Sil 8</li></ul>

Thermo Scientific TraceGOLD™ TG-5MS AMINE GC Columns

Thermo Scientific™ TraceGOLD TG-5MS AMINE GC Column enables analysis of ppm levels of amines without column priming.

<p><strong>Thermo Scientific™ TraceGOLD TG-5MS AMINE GC Column enables analysis of ppm levels of amines without column priming.</strong></p><ul><li>Low polarity phase, 5% diphenyl/95% dimethyl polysiloxane</li><li>Tubing surface is chemically altered to reduce tailing of active basic compounds</li><li>Also allows analysis of neutral or weakly acidic compounds (e.g., phenols) and compounds susceptible to hydrogen bonding</li><li>Low bleed at maximum operating temperature</li></ul><figure class="image"><img style="aspect-ratio:1394/854;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Trace_GOLD_TG_5_MS_AMINE_GC_columns_0e35235e21/Pragolab-GC-kolona-TraceGOLD-TG-5MS-AMINE-GC-columns.jpg" alt="Thermo Scientific: TraceGOLD™ TG-5MS AMINE GC Columns" width="1394" height="854"></figure><h4><strong>Recommended for:</strong></h4><ul><li>Amines and other basic compounds, including alkylamines, diamines, triamines, ethanolamines</li><li>Nitrogen-containing heterocyclics</li></ul>

Thermo Scientific TraceGOLD™ TG-5SilMS GC Columns

Thermo Scientific™ TraceGOLD™ TG-5SilMS GC Columns incorporate phenyl groups in the polymer backbone for improved thermal stability, reduced bleed and reduced susceptibility to oxidation.

<p><strong>Thermo Scientific™ TraceGOLD™ TG-5SilMS GC Columns incorporate phenyl groups in the polymer backbone for improved thermal stability, reduced bleed and reduced susceptibility to oxidation.</strong></p><ul><li>Low polarity, silarylene phase with selectivity comparable to 5% diphenyl/95% dimethyl polysiloxane</li><li>Designed for low bleed and outstanding inertness<br>&nbsp;</li></ul><figure class="image"><img style="aspect-ratio:1330/809;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Trace_GOLD_TG_5_Sil_MS_GC_columns_6f0b7c025e/Pragolab-GC-kolona-TraceGOLD-TG-5SilMS-GC-columns.jpg" alt="Thermo Scientific: TraceGOLD™ TG-5SilMS GC Columns" width="1330" height="809"></figure><h4><strong>Recommended for:</strong></h4><ul><li>GC/MS applications using ion-trap systems</li><li>Polycyclic aromatics</li><li>Hydrocarbons including chlorinated hydrocarbons</li><li>Phthalates</li><li>Phenols</li><li>Amines</li><li>Organophosphates</li></ul><h4><strong>Similar to:</strong></h4><ul><li>DB-5MS</li><li>VF-5ms</li><li>CP-Sil 8 Low-Bleed/MS</li><li>Rxi-5Sil MS</li><li>BPX5, ZB-5ms</li><li>Optima-5MS</li><li>SLB-5</li></ul>

Thermo Scientific TraceGOLD™ TG-5SILMS Guard GC Columns with SafeGuard

Thermo Scientific™ TraceGOLD™ TG-5SILMS Guard GC Columns with SafeGuard offer benefit of integrated SafeGuard for extended column lifetime

<p><strong>Thermo Scientific™ TraceGOLD™ TG-5SILMS Guard GC Columns with SafeGuard offer the benefit of an integrated SafeGuard for extended column lifetime.</strong></p><p>Using a guard column with a TraceGOLD TG-5SILMS GC column will lead to greater consistency in results over a longer period of time.</p><ul><li>With integrated SafeGUARD</li><li>Available in a range of phases</li></ul><h4><strong>For Use With (Application)</strong></h4><ul><li>GC/MS applications using ion-trap systems</li><li>Polycyclic aromatics</li><li>Hydrocarbons including chlorinated hydrocarbons</li><li>Phthalates</li><li>Phenols</li><li>Amines</li><li>Organophosphates</li></ul>

Thermo Scientific TraceGOLD™ TG-225MS GC Columns

Achieve higher thermal stability and increased efficiency using the Thermo Scientific™ TraceGOLD™ TG-225MS GC Columns.

<p><strong>Achieve higher thermal stability and increased efficiency using the Thermo Scientific<sup>TM</sup> TraceGOLD<sup>TM</sup> TG-225MS GC Columns.</strong></p><h4><strong>Engineered for Superior Performance</strong></h4><ul><li>Polar phase, 50% cyano propylmethyl/50% phenylmethyl polysiloxane</li><li>Innovative deactivation process for siloxane to reduce tailing and improves efficiency over comparable columns</li><li>Equivalent to USP G7, G19 phases<br>&nbsp;</li></ul><figure class="image"><img style="aspect-ratio:1331/817;" src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Pragolab_GC_kolona_Trace_GOLD_TG_225_MS_GC_columns_3085e09816/Pragolab-GC-kolona-TraceGOLD-TG-225MS-GC-columns.jpg" alt="Thermo Scientific: TraceGOLD™ TG-225MS GC Columns" width="1331" height="817"></figure><h4><strong>A Leap Forward in Column Performance with Low Bleed and Superior Inertness</strong></h4><ul><li>This low-bleed, stable column produces consistent results, and the low baseline noise enables improved limits of detection with enhanced resolution of low-level analytes.</li><li>Minimizing column bleed extends column lifetime, leading to higher productivity.</li><li>Reducing column bleed increases reproducibility of the stationary phase over time, resulting in greater run-to-run and batch-to-batch reproducibility.</li><li>Superior inertness ensures excellent peak shape and sensitivity, especially for highly active or difficult-to-analyze compounds.</li></ul><h4><strong>Recommended for:</strong></h4><ul><li>Alditol acetates (sugars)</li><li>FAMEs</li><li>Alternative Uses:</li><li>Ketones</li></ul><h4><strong>Similar to:</strong></h4><ul><li>Rtx™-225</li><li>DB-225</li><li>HP-225</li><li>SPB™-225</li></ul>

Thermo Scientific™ ProSightPD Software

Perform comprehensive analysis of top-down proteomics data with Thermo Scientific™ ProSightPD™ software.

<div container-id="cq-colctrl-lt8" comp-id="B1"><div><h3><strong>Confident proteoform identification and characterization</strong></h3></div></div><div container-id="cq-colctrl-lt8" comp-id="B2"><div><p><strong>Uncover and confidently characterize proteoforms within complex matrices, including proteoforms containing truncations, alternative splices, and post-translationally modified proteins.</strong>&nbsp;</p><p>Extensive searches make use of <strong>various fragmentation methodologies (e.g., ETD, HCD, UVPD)</strong>, allowing you to make full use of the high-quality <strong>MS/MS data</strong> obtained when searching against the<strong> full biological complexity present in UniProt. </strong>With<strong> Thermo Scientific ProSightPD software, </strong>see what is really there and make the most of your data.</p><div><h3><strong>Key benefits</strong></h3><h5><strong>Sophisticated tools at your fingertips</strong></h5><p><strong>Utilize several search modes</strong> for identifying intact and truncated proteins. ProSightPD software offers the ability to search entire raw files or quickly select specific MS<sup>2</sup> scans for further searching. Information in UniProt enables the identification of modified or processed proteins.</p><h5><strong>Remove the guesswork from database management</strong></h5><p><strong>Import result files </strong>from<a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1782"><strong> Proteome Discoverer</strong></a><strong> software</strong> or entire proteomes via UniProt formatted XML and FASTA files with Database Manager. Fully customize imported databases using thr<strong> ProSight Annotator GUI </strong>to characterize PTMs, disulfide bonds, mutations and truncations.</p><h5><strong>Intuitive user interface</strong></h5><p><strong>Analyze large datasets</strong> with many data files using <strong>ProSightPD nodes for </strong><a target="_blank" rel="noopener noreferrer" href="https://lcms.labrulez.com/products/1782"><strong>Proteome Discoverer</strong></a><strong> software. </strong>Create multi-step searches and utilize built in results interpretation tools.</p><h3><strong>Search Types</strong></h3><div><p><strong>Different database search modes</strong> allow you to optimize data interrogation based upon your experimental needs. Searches are driven through the use of a node-based system allowing flexibility of experimental design.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Pro_Sight_PD_Software_8a96430534.jpeg" alt="Thermo Scientific™ ProSightPD Software: ProSightPD Database Searching." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Pro_Sight_PD_Software_8a96430534.jpeg 245w," sizes="100vw" width="960" height="540"></p><div><p>Further information relating to the two search modes, Absolute Mass Search and Biomarker Search.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Pro_Sight_PD_Software_2_01f6c31076.jpeg" alt="Thermo Scientific™ ProSightPD Software: Complementary Search Types: Digging Deeper in Complex Samples." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Pro_Sight_PD_Software_2_01f6c31076.jpeg 245w," sizes="100vw" width="960" height="540"></p><h3><strong>Database Management</strong></h3><div><p><strong>Confident proteoform identification </strong>is realized through the use of XML-formatted databases, ensuring that nothing is missed.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Pro_Sight_PD_Software_3_db19f0cee9.jpeg" alt="Thermo Scientific™ ProSightPD Software: Database Manager: Add remove isoforms and PTMs." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Pro_Sight_PD_Software_3_db19f0cee9.jpeg 245w," sizes="100vw" width="960" height="540"></p><div><p><strong>Improvements to data visualization</strong> ensure that you can better interact with and interpret your data, minimizing the time taken to deliver actionable results.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Pro_Sight_PD_Software_4_575aa9dff5.jpeg" alt="Thermo Scientific™ ProSightPD Software: LFQ Visualizations." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Pro_Sight_PD_Software_4_575aa9dff5.jpeg 245w," sizes="100vw" width="960" height="540"></p><h3><strong>ProSightPD nodes</strong></h3><p><strong>Top-Down Workflows:</strong> ProSightPD&nbsp;includes templates to easily build the most commonly used-top down data analysis workflows.</p><p><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Thermo_Scientific_Pro_Sight_PD_Software_5_4f28a7434d.jpg" alt="Thermo Scientific™ ProSightPD Software: ProSightPD 2.0: Tailored Workflows for All Types of Data." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Thermo_Scientific_Pro_Sight_PD_Software_5_4f28a7434d.jpg 245w," sizes="100vw" width="740" height="400"></p></div></div></div></div></div></div></div>

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