Always on, always ready — high-resolution capillary IC in a compact platform
The Dionex ICS-4000 is the world’s first dedicated capillary high-pressure reagent-free ion chromatography (HPIC) system. Designed for high-resolution, low-flow separations, it delivers exceptional chromatographic performance, fast analysis times, and 24/7 on-demand readiness. With integrated control, capillary-optimized detectors, and minimal eluent consumption, it offers a new standard for reliable, low-maintenance ion chromatography.
Key Features and Benefits
🧪 Capillary HPIC Performance
- Supports high-pressure separations with 4 µm columns
- Fast, high-resolution gradients in minutes
- Continuous operation with no equilibration needed
♻️ Reagent-Free Simplicity
- Eluent generation from deionized water via EGC cartridge
- Just 15 mL of water/day for continuous operation
- Eluent cartridges last up to 18 months
🧠 Integrated Smart Design
- Fully integrated system in compact footprint
- Tilt-up lid, color-coded connections, and pre-cut tubing
- Vacuum degassing, seal wash (option), and inline shut-off valves
🧲 Versatile Detection Options
- Conductivity Detector (CD) – with self-regenerating suppressor
- Electrochemical Detector (ED) – ideal for cyanide, amines, carbohydrates
- QD Charge Detector – signal proportional to ion charge and concentration
🔁 Flexible Column Chemistry
- Compatible with over 20 capillary columns
- Suitable for a wide range of inorganic and organic ions, sugars, acids, amines
Thermo Scientific™ Dionex™ ICS-4000 Capillary HPIC™ System
Automation and Sample Handling
- Compatible with Dionex AS-DV and AS-AP autosamplers
- Advanced prep (dilution, derivatization, matrix removal)
- Supports vials, well plates, and <30 s injection cycles
- Optional Sample Conductivity & pH Accessory with conditional logic
Software Integration
- Controlled by Chromeleon™ Chromatography Data System (CDS)
- eWorkflows™ simplify analysis from injection to report
- Interactive charts and MiniPlots for intuitive data interpretation
Ideal for Applications in
- Food and beverage (e.g., sugars, organic acids, preservatives)
- Environmental (e.g., drinking water, wastewater)
- Pharmaceutical (e.g., excipients, counterions)
- Educational and routine analytical labs

