The KPV Analysis is a targeted laboratory test designed to confirm the identity, determine the amount, and assess the purity of KPV in lyophilised vials and raw active pharmaceutical ingredient (API) powders.
For lyophilised samples, results are reported in milligrams per vial together with purity. Raw API powders can be evaluated using purity in % (m/m).
About KPV
In this analysis, KPV refers to 2-oxo-5-phenylpentanoic acid, also known as 5-phenyl-2-keto-valeric acid. It is a small organic α-keto acid with the molecular formula C11H12O3.
2-Oxo-5-phenylpentanoic acid has been used as a research compound in biochemical and medicinal chemistry studies, including investigations involving enzyme–substrate interactions and α-keto acid derivatives.
Key Features
- Targeted identification and quantification of KPV
- Suitable for lyophilised vials and raw API powders
- Analysis by HPLC
- Results for lyophilised samples reported in mg per vial
- Alternative purity reporting in % (m/m) for raw API powders
- Minimum sample amount of one whole unopened vial with lyophilisate
- Minimum sample amount of 30 mg for raw API powders
- Average turnaround time of 7 business days
Analysis Parameters
- Target compound: KPV
- Other name: 2-oxo-5-phenylpentanoic acid
- CAS number: 88768-11-0
- Molecular weight: 192
- Testing method: HPLC
- Minimum amount of target compound for evaluation: Less than 1/20 of the usual dosage per vial
- Result format for lyophilised samples: mg per vial and peptide purity
- Result format for raw API powders: Purity in % (m/m) and peptide purity
- Minimum sample amount for lyophilised samples: One whole unopened vial with lyophilisate
- Minimum sample amount for raw API powders: 30 mg in a sealed glass vial to prevent the sample from absorbing moisture
- Average turnaround time: 7 business days
Important Notice
- In this analysis, KPV refers specifically to 2-oxo-5-phenylpentanoic acid (CAS 88768-11-0).
- This analysis is specifically intended for KPV. It does not automatically screen the sample for related compounds, degradation products, contaminants, or undeclared substances.
- For lyophilised samples, one whole unopened vial containing lyophilisate is required.
- Raw API powder should be supplied as at least 30 mg in a sealed glass vial to minimise moisture absorption.
Optional Additional Analyses
The following optional laboratory services are available:
- TFA Analysis
- Complete Raw Analytical Data
- Fentanyl Screening
- Alternative Result Format: Purity in % (m/m)
- Batch Variance Testing
- pH Measurement
- Endotoxin Analysis
- LCMS Screening for Peptide Contamination
- Sterility Testing (TAMC + TYMC)
- Heavy Metals Analysis (As, Cd, Pb, Hg)
- Additional Laboratory Report
