We are pleased to announce that a maintenance release is now available for KnowItAll 2025.Maintenance releases are an important way to introduce improvements and bug fixes between major releases to make sure users get the most out of KnowItAll solutions.Late 2024, we announced the KnowItAll 2025 major release featuring the new LC Expert tool, KnowItAll Data Control, KnowItAll Drug Classification Models, and various advances for spectral analysis workflows. This is the first update available after that release.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_Know_It_All_LC_Expert_Streamline_component_identification_with_the_power_of_the_new_Know_It_All_LC_Expert_s_automated_workflow_84a090a7c2.jpg" alt="Wiley: NEW! KnowItAll LC Expert: Streamline component identification with the power of the new KnowItAll LC Expert’s automated workflow." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_Know_It_All_LC_Expert_Streamline_component_identification_with_the_power_of_the_new_Know_It_All_LC_Expert_s_automated_workflow_84a090a7c2.jpg 245w," sizes="100vw" width="1735" height="960"><img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_Know_It_All_drug_classification_models_25277cc5e0.jpg" alt="Wiley: NEW! KnowItAll drug classification models." srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_Know_It_All_drug_classification_models_25277cc5e0.jpg 245w," sizes="100vw" width="603" height="324">We encourage users to ensure they are using the most recent version of the software for best performance.<blockquote>Current users can <a target="_blank" rel="noopener noreferrer" href="https://get.knowitall.com/Download?_gl=1*18h0vjr*_gcl_au*Mjk3ODY0Mzg1LjE3MTMyNzcyMDEuMTkwNDkyNDI4NS4xNzEzMzY3NDc0LjE3MTMzNjc0Nzk.">download the most recent version here</a>.</blockquote><h4>Learn more about KnowItAll 2025:&nbsp;&nbsp;</h4><ul><li><a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/whats-new-in-knowitall-2025/">What's New&nbsp;</a> &nbsp;&nbsp;</li><li><a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/knowitall-version-history/">Version History</a></li></ul><h4>About KnowItAll</h4>KnowItAll Software offers solutions to analyze and manage multiple types of spectral and chemical data in multiple file and instrument formats. KnowItAll's integrated toolsets eliminate the need for multiple software packages and increase overall lab efficiency and staff proficiency. Combined with Wiley’s comprehensive, high-quality spectral reference libraries, it provides an unparalleled solution for fast, reliable spectral analysis.<h4>About Wiley</h4>Wiley (NYSE: WLY) is one of the world’s largest publishers and a trusted leader in research and learning. Our industry-leading content, services, platforms, and knowledge networks are tailored to meet the evolving needs of our customers and partners, including researchers, students, instructors, professionals, institutions, and corporations. We empower knowledge-seekers to transform today’s biggest obstacles into tomorrow’s brightest opportunities. For more than two centuries, Wiley has been delivering on its timeless mission to unlock human potential. Visit us at <a target="_blank" rel="noopener noreferrer" href="https://www.wiley.com/en-ie">Wiley.com</a>.&nbsp;

KnowItAll 2025 Maintenance Release 2025.1 Available

Wiley, a global leader in authoritative content and research intelligence, today announced the release of additional data to its IR, Raman, LC-MS, and SmartSpectra libraries, significantly broadening compound coverage. The expansion brings Wiley's spectral database offerings to over 9.5 million high-quality spectra, delivering researchers enhanced capabilities for faster, more confident compound identification.“These updates deliver what researchers need most: broader coverage and greater confidence in their identifications,” said Graeme Whitley, senior director, Wiley Science Solutions. “By expanding our empirical collections, including updates to our renowned Sadtler IR and Raman libraries, alongside our SmartSpectra databases, we're providing quality data researchers can rely on to make critical decisions across their analytical workflows.”Subscribers automatically gain access to new data, ensuring labs always have the most current, reliable reference libraries to improve analysis, reduce errors, and increase productivity.<h4>KnowItAll Raman Spectral Library Collection</h4>The KnowItAll Raman collection has been expanded with 941 new spectra, bringing the total to more than 28,000 spectra. Two entirely new databases have been introduced: Raman – Drugs and Raman – Non-minerals.In addition, existing databases have been enriched with new content, including:<ul><li>600 spectra added to Raman – Sadtler Polymers &amp; Monomers (Basic 3)</li><li>200 spectra added to Raman – Minerals</li><li>16 spectra added to Raman – Polymers – Wiley</li></ul>These updates significantly strengthen Raman identification capabilities across polymers, minerals, and pharmaceutical compounds.<h4>KnowItAll IR Spectral Library Collection</h4>The KnowItAll IR collection has grown by more than 2,000 spectra, reaching a total of over 343,000 spectra. Three new databases have been added: IR – Contaminants, IR – Drugs, and IR – Polymers.An additional 100 spectra have also been incorporated into the IR – Minerals database, further expanding inorganic compound coverage.<h4>KnowItAll LC-MS Library Collection</h4>The KnowItAll LC-MS collection received one of the largest updates, with 497,000 new spectra added, representing an 18% increase. The collection now contains more than 3.2 million spectra.Seven new empirical LC-MS databases have been introduced, covering a broad range of application areas:<ul><li>LC-MS – Lipids Library</li><li>LC-MS – Pharmaceutical Compounds Library</li><li>LC-MS – Natural Products Library</li><li>LC-MS – Food Related Compounds Library</li><li>LC-MS – Environmental Compounds Library</li><li>LC-MS – General Compounds Library</li><li>LC-MS – Metabolites Library</li></ul>These additions greatly enhance support for untargeted screening, metabolomics, and complex mixture analysis.<h4>Wiley SmartSpectra IR Database Collection</h4>The SmartSpectra IR collection has nearly doubled in size with the addition of more than 249,000 spectra, bringing the total to over 499,000 spectra. Ten new databases have been added, covering critical compound classes such as lipids, endocrine disruptors, drugs, PFAS, pesticides, and additional emerging contaminants.<h4>Wiley SmartSpectra Raman Database Collection</h4>The SmartSpectra Raman collection experienced a major expansion, with over 100,000 new spectra added, representing a 300%+ increase. The collection now includes more than 133,000 spectra.Five new databases have been introduced, focusing on high-interest areas including lipids, PFAS, endocrine disruptors, cosmetics, and fragrances.<h4>Wiley SmartSpectra Vapor Phase IR Database Collection</h4>The SmartSpectra Vapor Phase IR collection has been expanded with more than 3,000 new spectra, increasing the total to over 218,000 spectra. Five new databases have been added, covering lipids, endocrine disruptors, fragrances, cosmetics, and PFAS—supporting improved analysis of volatile and semi-volatile compounds.By combining Wiley's empirical and SmartSpectra collections, researchers now have access to over 1 million IR spectra and over 161,000 Raman spectra—including the renowned Sadtler Libraries available exclusively through KnowItAll. SmartSpectra extends researchers' reach into chemical space beyond what's available in empirical libraries alone, enabling identification of compounds that haven't yet been physically measured.<img src="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/Wiley_Wiley_adds_additional_data_to_its_Smart_Spectra_IR_Raman_and_LC_MS_libraries_2_35fae897f7.jpg" alt="Wiley: Wiley adds additional data to its SmartSpectra, IR, Raman, and LC-MS libraries" srcset="https://storage.googleapis.com/labrulez-bucket-strapi-h3hsga3/thumbnail_Wiley_Wiley_adds_additional_data_to_its_Smart_Spectra_IR_Raman_and_LC_MS_libraries_2_35fae897f7.jpg 245w," sizes="100vw" width="1556" height="883">Wiley's comprehensive spectral database collections provide access to millions of high-quality spectra across a range of techniques, including IR, MS, NMR, Raman, and UV-Vis. These resources play a vital role in the interpretation, identification, verification, and classification of spectra across applications including pharmaceuticals, environmental science, forensics, materials research, and food safety.<blockquote><ul><li><a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/spectral-databases/">Learn more HERE</a></li><li><a target="_blank" rel="noopener noreferrer" href="https://sciencesolutions.wiley.com/how-to-update-knowitall-databases">Current subscribers can ensure they are up to date</a></li></ul></blockquote><h4>About Wiley</h4>Wiley (NYSE: WLY) is a global leader in authoritative content and research intelligence for the advancement of scientific discovery, innovation, and learning. With more than 200 years at the center of the scholarly ecosystem, Wiley combines trusted publishing heritage with AI-powered platforms to transform how knowledge is discovered, accessed, and applied. From individual researchers and students to Fortune 500 R&amp;D teams, Wiley enables the transformation of scientific breakthroughs into real-world impact. From knowledge to impact—Wiley is redefining what's possible in science and learning. Visit us at <a target="_blank" rel="noopener noreferrer" href="https://www.wiley.com/en-ie/">Wiley.com</a>.

Wiley adds additional data to its SmartSpectra, IR, Raman, and LC-MS libraries

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Wiley KnowItAll LC-MS Database Collection

KnowItAll LC-MS Library offers access to impressive collection of over 2.7 million high-quality mass spectra designed to accelerate spectral identification.

The KnowItAll LC-MS Library offers access to an impressive collection of over 2.7 million high-quality mass spectra designed to accelerate spectral identification.

<h4>KnowItAll LC-MS Library: Confident Identification Starts Here</h4>Access over 2.7 million high-quality LC-MS spectra with the KnowItAll LC-MS Library—designed to accelerate and streamline compound identification and classification.<h5>Key Features:</h5><ul><li>Includes four trusted LC-MS databases covering lipids, PFAS, polymers, drugs, and more</li><li>Each record features spectra, chemical structures, and metadata</li><li>Continuously updated to provide the latest compound coverage</li><li>Compatible with most MS instrument formats</li><li>Expert-reviewed for data accuracy and reliability</li></ul><h5>Applications:</h5>Ideal for environmental analysis, food safety, metabolomics, clinical research, QC, and more. This collection supports fast, reliable LC-MS workflows in both research and routine lab settings.<h5>Database Coverage:</h5><ul><li>LC-MS – Class Rule-Based PFAS Library: Over 7,000 spectra</li><li>LC-MS – Class Rule-Based Polymer Library: Over 202,000 spectra</li><li>LC-MS – Class Rule-Based Lipids Library: Over 2.5 million spectra</li><li>Wiley Registry of Tandem Mass Spectral Data: MSforID: 12,000 spectra</li></ul>Extend your coverage with optional NIST bundles and other spectral libraries.

Wiley KnowItAll LC-MS Database Collection

KnowItAll LC-MS Library: Confident Identification Starts Here

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Wiley adds additional data to its SmartSpectra, IR, Raman, and LC-MS libraries

KnowItAll 2025 Maintenance Release 2025.1 Available

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