XSelect CSH C18 columns are general purpose C18 columns that provide alternative selectivity compared to other C18 sorbents. Charged Surface Hybrid (CSH) technology enables superior peak shape and increased loading capacity for basic compounds. Packed in ultra-low dispersion hardware, 2.5 µm eXtended Performance [XP] columns enable exceptional separation performance, robustness and throughput for HPLC assays while enabling a seamless transition path toward UPLC adoption.
Waters: XSelect CSH C18 Column
Specifications
- Chemistry: C18
- Separation Mode: Reversed Phase
- Particle Substrate: Hybrid
- pH Range Min: 1 pH
- pH Range Max: 11 pH
- Maximum Pressure: 10000 psi (690 Bar)
- Endcapped: Yes
- Silanol Activity: Low
- Particle Shape: Spherical
- Pore Size: 130 Å
- System: UHPLC, UPLC
- Particle Technology: CSH
- USP Classification: L1
- Carbon Load: 15 %
The Waters XSelect CSH C18 HPLC Column is also available in these types:
Waters XSelect CSH C18 Column with eConnect Column Tag
- This column comes equipped with an electronic eConnect column tag containing unique column-specific information. These NFC-enabled device-tagged columns were developed to automatically identify, track and digitally trace column use history. eConnect columns can be used on any HPLC, but its advantages are unlocked when used with the Waters Alliance iS System running Empower software.
Waters: XSelect CSH C18 Column with eConnect Column Tag
XSelect Peptide CSH C18 Column
- Waters XSelect CSH C18 contain a low and carefully-defined concentration of positive charges that yield comparatively excellent peak shape for peptides using either FA- or TFA-containing mobile phases. The fact that the performance of a CSH C18 column exhibits little dependence on strong ion pairing agents makes it ideal for LC or LC-MS applications
- Maximum Pressure: 6000 psi (415 Bar)
- System: HPLC
XSelect Columns
Achieve unmatched reproducibility with a wide range of selectivity
Quickly and easily develop robust methods compatible with all modern chromatographic detection modes and transfer them from lab to lab with the XSelect Column family.
Designed to help you achieve reproducible and highly selective chromatographic separations, the XSelect Column family features two base particles technologies, Charged Surface Hybrid (CSH) and High Strength Silica (HSS). With XSelect Columns, method development scientists like you can achieve a wide range of selectivities across all application areas, without compromising performance.
Overview
- Designed for selectivity and stability at low pH
- Superior peak shape for basic compounds
- Highest analyte mass loading available
- Excellent batch-to-batch reproducibility
- Ideal for rapid method development
- CSH Column chemistries: C18, Fluoro-Phenyl (PFP), and Phenyl-Hexyl, available in 2.5 XP, 3.5, 5 μm analytical and 10 μm OBD preparative sizes
- HSS Column chemistries: HSS C18, C18 SB, and T3, available in 2.5 XP, 3.5, and 5 μm particle sizes
- Prolonged column lifetimes with optional VanGuard Cartridges specifically designed using XSelect stationary phases
- Recommended Use: For improving selectivity, peak shape, and retentivity in methods development.
Waters: XSelect Columns


