KNAUER Eurospher II 100 C18P Prep HPLC Columns (USP L1)KNAUER´s most unpolar C18P phase with excellent shape selectivity. It features polymeric, high efficiency endcapping of 99 % and 20 % carbon content, exceptional pH stability in the range of 1–12.
Features

KNAUER Eurospher II 100 C18P Prep HPLC Columns (USP L1)

C18P columns with trifunctional modifications (USP L1): Hydrophobic and stearic interactions

KNAUER´s most unpolar C18P phase with excellent shape selectivity. It features polymeric, high efficiency endcapping of 99 % and 20 % carbon content, exceptional pH stability in the range of 1–12, and outstanding mechanical and chemical stability.

Properties
  • Separation mechanism: Hydrophobic and stearic interaction
  • Ultra pure, spherical high performance HPLC phase based on silica gel
  • Unpolar, trifunctional C18 (Octadecyl) modification, high efficiency endcapping, with 20 % carbon content (~ 99 % endcapping) 
Key features
  • KNAUER´s most unpolar C18 phase, polymeric, high efficiency endcapping of 99 % and 20 % carbon content, higher pH stability in the range of 1-12, outstanding mechanical and chemical stability, suited for analytical as well as semi preparative and preparative applications.
Recommended application areas
  • Alternative selectivity to standard C18; stationary phase in Eurospher II C18 family with the highest carbon load; fully endcapped; excellent shape selectivity and pH stability.

KNAUER: C18PKNAUER: C18P

Tip: Not all C18 phases are comparable! When replacing an existing column, always have a close look at the characteristics like carbon load, pore size and specific surface area.

Stationary phase Eurospher II 100 C18P is provided in these column types: analytical, semi-preparative and preparative.

Eurospher II 100 C18P Preparative Standard Columns are available with these parameters:

  • Column length (mm): 50, 150, 250
  • Column ID (mm): 20, 30, 50
  • Particle size (µm): 5, 10, 15

Eurospher II 100 C18P Preparative dAX Columns with dynamic axial compression are available with these parameters:

  • Column length (mm): 50, 150, 250
  • Column ID (mm): 25, 30, 50
  • Particle size (µm): 5, 10, 15

KNAUER Preparative HPLC Columns

The right choice for all dimensions from semi-prep to batch chromatography to SMB.

  • Modifications: Reversed Phase, HILIC, Normale Phase
  • Max. Pressure: 400–600 bar
  • Column Inner Diameter (ID): 16–50 mm in our shop, more on request
  • Column Brands: Eurospher, Eurospher II
  • Safe Investment: Robustness and durability based on superior technology
  • Application: Easy upscaling, as all materials are available from ultra high performance to preparative scale HPLC. You can also use our upscaling calculator.
  • Customizable: Standard flanged hardware & dAX hardware with static or dynamic axial compression available

KNAUER: KNAUER Preparative HPLC ColumnsKNAUER: KNAUER Preparative HPLC Columns

Preparative HPLC columns can be offered with two different hardware types:
  • Versatile standard flanged hardware for nearly any application task in batch chromatography
  • dAX Hardware with static and dynamic axial compression for an extended lifetime and multi-column chromatography like SMB processes
 

News

News from LabRulezLCMS Library - Week 17, 2025
Article | Application

News from LabRulezLCMS Library - Week 17, 2025

This week we bring you application notes by Shimadzu and Waters Corporation, presentation by Agilent Technologies and technical notes by Knauer and Thermo Fisher Scientific!