The new ULDC (ultra low dispersion chromatography) system meets the enormous requirements that are essential to minimize extra column volume and thus peak dispersion.
- Ultra low dispersion volume due to optimized injection, flow and detection components
- Conventional method (also gradient) can directly be transfered to ULDC system without any adaptations
- Sharper early-eluting peaks generate better sensitivities and resolution
Eluent delivery
The Pump P6.1L with a HPG configuration features a solvent selection valve to set up to 4 solvents to the system of which two can be blended simultaneously. The internal degassing unit will prevent air bubbles in the system. Every P 6.1L comes with an attached mixing chamber, which can be changed to a larger volume depending on the applications needs.
Knauer: High pressure gradient HPLC pump - AZURA P 6.1L High Pressure Pump with 10 ml pump head, stainless steel
Sample Injection
The Autosampler 6.1L can inject 0.1 – 5000 µl to have a large flexibility. Using standard vials or two microtiter plates will give you a maximum sample capacity of up to 768 samples or 108 vials.
Column thermostating
The Column thermostat CT 2.1 is suitable for column thermostatization above and below room temperature. The instrument operates with a microprocessor controlled Peltier element for exact temperature settings.
Chromatography data system
KNAUER ClarityChrom® is a powerful, yet easy-to-use chromatography software for instrument control, data acquisition and data processing. It is an economical solution compared to other more complex chromatography software while still offering FDA 21 CFR Part 11 compliance.
Detection
The detector DAD 2.1L features a novel light path and flow cell architecture with improved handling and excellent performance. This Diode array detector can be used in the wavelength range of 190-700 nm.
Knauer: KNAUER AZURA 1240 bar UHPLC System - AZURA DAD 6.1L Diode array detectors (DAD or PDA)
This AZURA ULDC system can be customized with several detectors:
- The diode array detector DAD 6.1L covers all conceivable applications with a spectral range of 190-1000 nm. With its novel light path and optimized flow cells, it is one of the most powerful devices on the market.
- The detector MWD 2.1L is an 8 channel, sensitive multiwavelength detector combining high performance with easy handling at an affordable price. This multiwavelength detector can be used in the wavelength range of 190-700 nm.
- The variable single wavelength UV/VIS detector UVD 2.1L comes with an installed deuterium lamp which covers a wavelength range from 190 to 750 nm. It is a competitively priced detector for routine HPLC applications including fast LC methods.
Customized configurations like combinations of several detectors are also available. Every AZURA 862 HPLC system can easily be upgraded to ULDC and it is not necessary to purchase a UHPLC system with higher back pressure capabilities.
Key Features
- Ultra sharp peaks
- Maximum separation power
- Ultra low extra column volume
- Better performance than HPLC
Technical Data
Analytical system
- Application area: UHPLC, HPLC
- Pump system: Gradient
- Gradient: Binary HPG
- Injection: Autosampler
- Detector: Diode array detection DAD
- Software: ClarityChrom, Mobile Control
- Pressure: 862 bar
- Column thermostat: Yes
Included components
AZURA Eluent tray E 2.1L
AZURA® Eluent tray E 2.1L for AZURA® devices with a capacity of 6 x 1 l bottles or 4 x 2.5 l bottles or 2 x 5 l bottles, (delivery without bottles)
Knauer: AZURA Eluent tray E 2.1L - Eluent tray for up to 6 x 1000 ml bottles, (delivery without bottles), or 4 x 2.5 l bottles, or 2 x 5 l bottles, or 1 x 10 l bottle
Set of eluent supply bottles for HPG and LPG systems incl. bottle for piston backflushing
Set of 4 eluent bottles 1000 ml, 1 bottle 250 ml for piston backflushing, incl. closed caps, GL45 use with AZURA tubing kit
High pressure gradient HPLC pump
AZURA® Pump P 6.1L (HPG), with 10 ml pump head (stainless steel), degasser and mixer (400 µl)
- Max. flow rate : 10 ml/min
- Pump head materials : Stainless Steel Gradient : High pressure gradient (binary)
- Pump features : Active pulsation compensation, RFID for automatic pump head detection, Integrated pressure sensor, Purge valve (manual), Leak management, Piston seal wash
- Maximum delivery pressure [MPa] : 86 MPa
Fast and versatile analytical HPLC autosampler
AZURA® Autosampler AS 6.1L analytical HPLC autosampler, 862 bar
- Maximum back pressure: 862 bar
- Sample loop: 100 µl
- Sample tray cooling: None
- Autosampler Flow Path: Analytical
Knauer KNAUER AZURA 1240 bar UHPLC System - autosampler AZURA AS 6.1L 1240 bar
Column thermostat for up to 8 HPLC columns
Column thermostat AZURA CT 2.1 for constant temperatures and reproducible results
- Temperature range : 5–85 °C
Basic Diode Array Detector for Liquid Chromatography and Process Technology
AZURA® Detector DAD 2.1L Diode array detector DAD 2.1L without flow cell 190 - 700 nm, incl. test cell
- Detector type: Diode array detector
- Detection channels: 8 (Digital)/4 (Analog)
- Wavelength range: 190 - 700 nm
- Number of diodes: 256
- Linearity: > 2.0 AU at 274 nm (ASTM E1657-98)
Standard KNAUER LightGuide UV Flow Cell Cartridge
10 mm path length, 2µl, 1/16", 50 bar, LightGuide Flow cell cartridge for AZURA® Detector DAD/MWD
- Flow cell type: Analytical UV flow cell
- Path length: 10 mm
- Capillary connection: 1/16''
- Max. flow rate: 5 ml/min
- Flow cell volume: 2 µl
Start-Up Kit with flexible, precut capillaries for analytical UHPLC and ULDC systems with 1/16" connections
Set of precut capillaries, fittings, connectors and adapters
Knauer: Start-Up Kit with flexible, precut capillaries for analytical UHPLC and ULDC systems with 1-16 connections
Tool kit AZURA
Tool Kit AZURA® for systems with PEEK or pre-cut capillary kits
8-port GBit switch for connection of AZURA devices with a PC
8-port LAN GBit switch NetGear GS108GE, 8x RJ-45, GBit, Auto MDI-X, power plug UK, US or AUS
ClarityChrom 9.1.0 - Workstation, autosampler control included
ClarityChrom® single instrument license for one time base
Knauer: ClarityChrom Workstation
ClarityChrom 9.1.0 - PDA extension
ClarityChrom® option for PDA data processing
Eluent waste kit for AZURA Analytical systems
Eluent waste kit for all AZURA Analytical systems, incl. filter, waste can and cap.


