Development of pH Gradient Mobile Phase Concentrates for Robust, High Resolution mAb Charge Variant Analysis

DESIGNING A NEW PARTICLE TECHNOLOGY AND PH GRADIENT MOBILE PHASE CONCENTRATES FOR ROBUST, HIGH RESOLUTION CHARGE VARIANT ANALYSIS OF MABS Paula Orens, Matthew A. Lauber, Qi Wang, Susan C. Rzewuski, Hua Yang, Stephan Koza, Mingcheng Xu, Mike F. Morris, Justin…

[ APPLICATION NOTE ] Designing a New Particle Technology for Robust Charge Variant Analysis of mAbs Matthew A. Lauber, Susan C. Rzewuski, Qi Wang, Hua Yang, Stephan Koza, MingCheng Xu, Mike Morris, Justin McLaughlin, Steve Shiner, and Bei Niu Waters…

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[ APPLICATION NOTE ] Optimizing LC-MS Separations of mAbs using a BioResolve SCX mAb Column and IonHance CX-MS pH Concentrates Andrew Schmudlach, Samantha Ippoliti, Qi Wang, and Matthew A. Lauber Waters Corporation, Milford, MA, USA APPLICATION BENEFITS INTRODUCTION A novel…