DESIGNING A NEW PARTICLE TECHNOLOGY AND PH GRADIENT MOBILE PHASE CONCENTRATES FOR ROBUST, HIGH RESOLUTION CHARGE VARIANT ANALYSIS OF MABS Paula Orens, Matthew A. Lauber, Qi Wang, Susan C. Rzewuski, Hua Yang, Stephan Koza, Mingcheng Xu, Mike F. Morris, Justin…
[ APPLICATION NOTE ] Development of pH Gradient Mobile Phase Concentrates for Robust, High Resolution mAb Charge Variant Analysis Qi Wang, Susan C. Rzewuski, and Matthew A. Lauber Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ INTRODUCTION Platform method…
[ APPLICATION NOTE ] Development of Monoclonal Antibody Charge Variant Analysis Methods Using a BioResolve SCX mAb Column Hua Yang, Bill Warren, and Stephan Koza Waters Corporation, Milford, MA, USA APPLICATION BENEFITS INTRODUCTION Method development parameters for cation Charge heterogeneity…
