[ TECHNOLOGY BRIEF ] Charge-Variant Analysis of Antibody-Drug Conjugates with Cation-Exchange Chromatography Qi Wang,¹ Hua Yang,¹ Jacquelynn Smith,² and Matthew A. Lauber¹ Waters Corporation, Milford, MA, USA,¹ and Pfizer, Inc., Chesterfield, MO, USA² Demonstrating the utility of BioResolve SCX mAb…
Key words
bioresolve, emtansine, variant, adcs, trastuzumab, ado, scx, charge, drug, antibody, mab, interactions, gradient, conjugation, conjugates