Improving LC-MS Separations of Peptides with Difluoroacetic Acid Ion Pairing Jennifer Nguyen, Xiaoxiao Liu, and Matthew A. Lauber Waters Corporation, Milford, MA, USA INTRODUCTION Peptide mapping is an important and critical technique in the characterization of biopharmaceuticals. These separations are…
[ APPLICATION NOTE ] Comparing Mobile Phase Additives for the Separation of mAb Tryptic Peptides: A Case Study on Formic, Difluoroacetic, and Trifluoroacetic Acid Jennifer M. Nguyen, Xiaoxiao Liu, and Matthew A. Lauber Waters Corporation, Milford, MA, USA APPLICATION BENEFITS…
[ APPLICATION NOTE ] Selecting a Reversed-Phase Column for the Peptide Mapping Analysis of a Biotherapeutic Protein Stephan M. Koza and Erin E. Chambers Waters Corporation, Milford, MA, USA APPLICATION BENEFITS ■■ ■■ Side-by-side performance of ten The peptide mapping…
Peptide Mapping and Small Protein Separations with Charged Surface Hybrid (CSH) C18 and TFA-Free Mobile Phases Matthew A. Lauber, Stephan M. Koza, Kenneth J. Fountain Waters Corporation, Milford, MA, USA A P P L I C AT I O N…
