Making Peptide Mapping Routine with the Agilent 6545XT AdvanceBio LC/Q-TOF

Application Note Biotherapeutics and Biosimilars In-depth Peptide Mapping with Iterative MS/MS Acquisition on the Agilent 6545XT AdvanceBio LC/Q‑TOF Authors Introduction Linfeng Wu and David L. Wong Agilent Technologies, Inc. Santa Clara, CA, USA Therapeutic monoclonal antibodies (mAbs) represent one of…

An Integrated Workflow for Peptide Mapping of Monoclonal Antibodies Application Note Biotherapeutics and Biosimilars Authors Introduction David L. Wong Monoclonal antibodies (mAbs) represent one of the fastest growing classes of drugs in the pharmaceutical industry. As a protein drug, the…

Agilent-NISTmAb Peptide Mapping Agilent BioHPLC Columns Application Compendium Contents Agilent-NISTmAb Standard (P/N 5191-5744; 5191-5745) was aliquoted from NISTmAb RM 8671 batch. Quality control (QC) testing is performed using Agilent LC-MS system. QC batch release test includes aggregate profile, charge variants…

Application Note Biotherapeutics and Biosimilars LC/MS/MS Peptide Mapping Comparison of Innovator and Biosimilars of Rituximab Author Suresh Babu C.V. Agilent Technologies, Inc. Abstract The development and manufacturing of biosimilars require comparability studies with innovator biotherapeutic products. This Application Note presents…