LC/MS/MS Peptide Mapping Comparison of Innovator and Biosimilars of Rituximab

Peptide Mapping of Innovator and Biosimilar Monoclonal Antibody Using an Agilent 1290 Infinity UHPLC Coupled to an Agilent 6550 iFunnel Q-TOF LC/MS System Application Note Author Introduction Ravindra Gudihal Monoclonal antibodies (mAbs) are becoming one of the important classes of…

Application Note Biotherapeutics and Biosimilars In-depth Peptide Mapping with Iterative MS/MS Acquisition on the Agilent 6545XT AdvanceBio LC/Q‑TOF Authors Introduction Linfeng Wu and David L. Wong Agilent Technologies, Inc. Santa Clara, CA, USA Therapeutic monoclonal antibodies (mAbs) represent one of…

Enhancing The Quality Of Peptide Mapping Separation For The Analysis Of PTM Application Note Biotherapeutics and Biosimilars Author Introduction Suresh Babu C.V. Post-translational modifications (PTMs) on proteins such as monoclonal antibodies (mAbs) are critical quality attributes (CQAs) that define the…

An Integrated Workflow for Peptide Mapping of Monoclonal Antibodies Application Note Biotherapeutics and Biosimilars Authors Introduction David L. Wong Monoclonal antibodies (mAbs) represent one of the fastest growing classes of drugs in the pharmaceutical industry. As a protein drug, the…