Analysis of Peptone Samples Using the Agilent InfinityLab 2D‑LC Solutions with Active Solvent Modulation

Technical Overview The Agilent InfinityLab 2D-LC Solution with Active Solvent Modulation Achieving Improved Resolution and Sensitivity for Challenging Combinations of Separation Conditions Author Sonja Krieger Agilent Technologies, Inc. Abstract A major challenge during method development in two-dimensional liquid chromatography (2D-LC)…

Application Note Pharma & Biopharma Multi-Attribute Analysis of Monoclonal Antibodies Using the Agilent InfinityLab 2D-LC Solution and Q-TOF MS Authors Gerd Vanhoenacker, Isabel Vandenheede, Pat Sandra, and Koen Sandra Research Institute for Chromatography (RIC) Kortrijk, Belgium Sonja Krieger, Sonja Schneider,…

Application Note Biopharma/Pharma Determination of Multiple Attributes of Monoclonal Antibodies Simultaneous and parallel multi-attribute analysis using 3D-LC/MS with 2D multimethod option mAb SEC Size variants Protein A CEX LC/MS mAb Titer Charge variants Mol wt (MW) AA sequence PTM Cell…

Application Note Biologics and Biosimilars Direct Analysis of In-Process Oligonucleotides Without Manual Purification Ion-pair reversed-phase LC analysis with online desalting using Agilent InfinityLab 2D-LC Solutions Authors Abstract Sonja Krieger and Clarissa Dickhut Agilent Technologies, Inc. Waldbronn, Germany Oligonucleotides synthesized using…