Development of high speed CYP cocktail inhibition assay using UHPLC-MS/MS

C190-E342 High-Throughput Analysis Enabled by Ultra-Fast Gradient with Nexera X4 × LCMS-8060 Series Technical Report Kosuke Nakajima1, Miho Kawashima1, and Keiko Matsumoto1 Abstract: LC-MS/MS is increasingly used even in clinical testing laboratories. Such laboratories need to reduce analysis times per…

C146-E232G Liquid Chromatograph Mass Spectrometer LCMS-8050 Speed and Sensitivity Beyond Comparison Continuing the evolution of Shimadzu’s UF technology, Shimadzu introduces the LCMS-8050 triple quadrupole mass spectrometer, offering unparalleled measurement speeds and high-sensitivity performance. High-sensitivity quantitation delivered at high speed Multi-component…

C146-E232F Liquid Chromatograph Mass Spectrometer LCMS-8050 Speed and Sensitivity Beyond Comparison Continuing the evolution of Shimadzu's UF technology, Shimadzu introduces the LCMS-8050 triple quadrupole mass spectrometer, offering unparalleled measurement speeds and high-sensitivity performance. High-sensitivity quantitation delivered at high speed Multi-component…

High-Throughput In Vitro ADME Analysis with Agilent RapidFire/MS Systems: Cytochrome P450 Inhibition Application Note Authors Vaughn Miller Agilent Technologies, Inc. Wakefield, MA, USA Introduction Analysis of cytochrome P450 (CYP) inhibition is an important component of the drug discovery process as…