Nitrosamines impurity analysis using SCIEX QTRAP® 4500 LC-MS/MS System Sensitive and reproducible LC-MS/MS based quantification method for NDMA in ranitidine API and drug products Nitrosamines are potent carcinogens in animals and humans, so they must be strictly controlled in pharmaceutical…
Analysis of Genotoxic Nitrosamines in Losartan and Ranitidine Active Pharmaceutical Ingredients On the SCIEX QTRAP® 4500 LC-MS/MS System with ExionLC™ AD System Sandeep Choudhary, Aman Sharma, M Chandrasekar, Manoj Pillai SCIEX, India In recent years, there have been several high…
Highly Selective and Sensitive Method for Quantification of Nitrosamines in Valsartan Drug Substances Quantification using SCIEX Triple Quad™ 5500+ LC-MS/MS System − QTRAP® Ready with an ExionLC™ AD System Aman Sharma1, Sandeep Choudhary1, M Chandrasekar1, Manoj Pillai1 SCIEX, India Valsartan…
NDMA impurity in Ranitidine / LCMSTM-8060 Application News Quantitative Determination of NDMA Impurity in Ranitidine Drug Products – Examples of Actual Samples Analysis by LCMS-8060 with APCI Zhe Sun1, Jie Xing1, Asri Minarni2, Zhaoqi Zhan1 1 Shimadzu Asia Pacific, Singapore,…
