Breath Biopsy: combining Thermal Desorption-Gas Chromatography with High Resolution Mass Spectrometry for improved sensitivity and selectivity in untargeted breath analysis

WHITE PAPER 10727 Breath Biopsy with TD-GC-Orbitrap: a non-invasive approach for disease detection Authors: Dominic Roberts1, Cristian Cojocariu1, Kayleigh Arthur2, Jonathan Lawson2; 1Thermo Fisher Scientific, Runcorn, UK; 2Owlstone Medical, Cambridge, UK Keywords: Breath Biopsy, early detection, respiratory disease, biomarkers, Thermal…

Breathomics Developing and optimizing a robust HRAM GC-MS pipeline for on-breath global biomarker analysis Dominic Roberts1, Paul Humphrey1, Shane Swann2, Luke Cartwright2, Simon Kitchen2, Stefano Patassini2 & Morad K Nakhleh2. 1Thermo Fisher Scientific, Hemel Hempstead, UK. 2Owlstone Medical Ltd, Cambridge,…

Large-scale targeted biomarker analysis of volatile organic compounds in breath by TD-GC-MS Darren Barrington-Light, Thermo Fisher Scientific, Altrincham, United Kingdom Mircea Martiniuc, Owlstone Medical Ltd, Cambridge, United Kingdom; Laercio Pires Fernandes Jr, Thermo Fisher Scientific, Altrincham, United Kingdom View Settings…

eBook Thermo Scientific Orbitrap Exploris GC 240 Mass Spectrometer Contents Foreword Overview Specifications Breakthrough performance of the Orbitrap Exploris GC for analytical testing and scientific research applications This study explores the power of high resolution and accurate mass using Orbitrap-based…